Incidence and Outcomes Associated With Clostridium difficile Infections: A Systematic Review and Meta-analysis [PDF]
Importance: An understanding of the incidence and outcomes of Clostridium difficile infection (CDI) in the United States can inform investments in prevention and treatment interventions.
Balkenende, Erin +15 more
core +1 more source
Introduction Clostridioides difficile infection (CDI) is a recognized global threat especially for vulnerable populations. It is of particular concern to healthcare providers as it is found in both hospital and community settings, with severe courses ...
Gordon Brestrich +15 more
doaj +1 more source
Identification of a novel zinc metalloprotease through a global analysis of clostridium difficile extracellular proteins [PDF]
Clostridium difficile is a major cause of infectious diarrhea worldwide. Although the cell surface proteins are recognized to be important in clostridial pathogenesis, biological functions of only a few are known.
A Barketi-Klai +73 more
core +16 more sources
Clinical Utility and Alterations in Bacterial Flora in Fecal Microbiome Transplantation
Dysbiotic states of gut ecology can be altered directly by transplantation of fecal preparation from healthy donors to patients with therapeutic intent.
Atman A. Dave, Rachel Robson
doaj +1 more source
Rethinking the role of alpha toxin in Clostridium perfringens-associated enteric diseases : a review on bovine necro-haemorrhagic enteritis [PDF]
Bovine necro-haemorrhagic enteritis is an economically important disease caused by Clostridium perfringens type A strains. The disease mainly affects calves under intensive rearing conditions and is characterized by sudden death associated with small ...
Deprez, Piet +6 more
core +3 more sources
Clostridium subterminale is an anaerobic spore-forming bacterium usually associated with infections in patients who are immunocompromised. This case report focuses on a rare presentation of a multifascial space odontogenic infection associated with the ...
Karin Davis +4 more
doaj +1 more source
The burden of clostridium difficile infection in patients with liver cirrhosis [PDF]
Clostridium Difficile Infection (CDI) has registered a dramatically increasing incidence in the general population over the past decades. Nowadays, Clostridium Difficile is the leading cause of hospital-acquired diarrhea in Europe and North America ...
Dumitru, Andrada +5 more
core +2 more sources
High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]
Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon +9 more
core +2 more sources
Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]
Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L. +13 more
core +1 more source
Gram-positive Rod Surveillance for Early Anthrax Detection
Connecticut established telephone-based gram-positive rod (GPR) reporting primarily to detect inhalational anthrax cases more quickly. From March to December 2003, annualized incidence of blood isolates was 21.3/100,000 persons; reports included 293 ...
Elizabeth M. Begier +4 more
doaj +1 more source

