Results 131 to 140 of about 73,615 (295)

TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models

The FEBS Journal, EarlyView.
The manuscript explores structural and functional features of TDP‐43 and its worm homologue, TDP‐1, highlighting conserved and divergent structural and functional features. Using genetically engineered C. elegans models, key pathological features of TDP‐43 proteinopathies—including aggregation, neurodegeneration, and motor deficits—are recapitulated ...
Ghulam Jeelani Pir, Joerg Buddenkotte, Majid Ali Alam, Ahmed Own, Randall J. Eck, Brian C. Kraemer, Eckhard Mandelkow, Martin Steinhoff   +7 more
wiley   +1 more source

Clozapine in the community [PDF]

British Journal of Psychiatry, 1992
Michael Phelan, Geraldine Strathdee, Karen Jones   +2 more
openaire   +3 more sources

Olanzapine Attenuates Cue-elicited Craving for Tobacco

, 2004
Rationale: Recent biological conceptualizations of craving and addiction have implicated mesolimbic dopamine activity as a central feature of the process of addiction. Imaging, and pharmacological studies have supported a role for dopaminergic structures
Hutchinson, Kent E, Niaura, Raymond, Pickworth, Wallace B, Rutter Goodworth, Marie-Christine, Sobik, Laura, Swift, Robert   +5 more
core  

Advancing evidence‐based practice through the Knowledge Translation Challenge: Nurses’ important roles in research, implementation science and practice change

Journal of Advanced Nursing, EarlyView.
Abstract Aim To describe a knowledge translation capacity‐building initiative and illustrate the roles of nurses in practice change using an exemplar case study. Design The report uses observational methods and reflection. Methods The Knowledge Translation Challenge program involves a multi‐component intervention across several sites.
Amanda Chisholm, Angela Russolillo, Michelle Carter, Marla Steinberg, Leah Lambert, Andrea Knox, Agnes Black   +6 more
wiley   +1 more source

Annual Research Review: Psychosis in children and adolescents: key updates from the past 2 decades on psychotic disorders, psychotic experiences, and psychosis risk

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 460-476, April 2025.
Psychosis in children and adolescents has been studied on a spectrum from (common) psychotic experiences to (rare) early‐onset schizophrenia spectrum disorders. This research review looks at the state‐of‐the‐art for research across the psychosis spectrum, from evidence on psychotic experiences in community and clinical samples of children and ...
Ian Kelleher
wiley   +1 more source

Focusing on an EEG Biomarker, the Photoparoxysmal Response (PPR), to Identify Promising Investigational Anti‐Seizure Medications (ASMs) and Differentiate the Efficacy of Existing ASMs

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Ronald C. Reed, Dorothee G. A. Kasteleijn‐Nolst Trenite   +1 more
wiley   +1 more source

Annual Research Review: Psychosis in children and adolescents – a call to action: a commentary on Kelleher (2025)

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 588-591, April 2025.
The spectrum of psychosis is highly relevant to child and adolescent mental health. Psychotic symptoms are common in children and adolescents. The onset of psychotic disorders is often preceded by neurodevelopmental problems in early childhood, and some 13% of adolescents attending specialist mental health services will later be diagnosed with a ...
James G. Scott
wiley   +1 more source

Clozapine-induced potentiation of latent inhibition is due to its action in the conditioning stage: implications for the mechanism of action of antipsychotic drugs [PDF]

, 1999
Eran Shadach, Joram Feldon, Ina Weiner
openalex   +1 more source

Subclinical hypomania, psychiatric and neurodevelopmental diagnoses: phenotypic and aetiological overlap

Journal of Child Psychology and Psychiatry, EarlyView.
Background Subclinical hypomanic symptoms are fairly common in the general population but are linked to psychiatric and neurodevelopmental conditions. However, the genetic and environmental origins of these associations are unclear. This twin study examined the phenotypic and aetiological associations between subclinical hypomania and psychiatric and ...
Georgina M. Hosang, Miriam I. Martini, Angelica Ronald, Henrik Larsson, Sebastian Lundström, Paul Lichtenstein, Mark J. Taylor   +6 more
wiley   +1 more source

Monitoring of Blood Clozapine Levels After a Change in Smoking Status for Patients Treated With Clozapine: A Clinical Audit From Hull Community Mental Health Team

BJPsych Open
Aims According to The Medicines and Healthcare products Regulatory Agency (MHRA) Drug safety update in August 2020 regarding clozapine, monitoring blood clozapine levels for toxicity is now advised in certain clinical situations such as when a patient ...
Kamran Mahmood, Odira Anakebe, Keshia Theobalds-Ward, Madhu Gulati   +3 more
doaj   +1 more source