Results 61 to 70 of about 63,990 (294)

Antipsychotic medication for childhood-onset schizophrenia [PDF]

open access: yes, 2007
We review the development of several new approaches for extending the performance of Brillouin based slow light systems. In particular we describe the use of cavity effects to enhance the achievable delays, gain saturation to decouple the delay and ...
Datta, Soumitra   +2 more
core   +2 more sources

Clozapine in pregnancy

open access: yesIndian Journal of Psychiatry, 2006
This report describes the case of a woman with treatment-resistant schizophrenia who became pregnant while being treated successfully with clozapine. Possible risks associated with continuation of clozapine during pregnancy are discussed.
openaire   +4 more sources

The Lung Microbiome Modulates Pain‐Like Behavior Via the Lung–Brain Axis in a Nitroglycerin‐Induced Chronic Migraine Mouse Model

open access: yesAdvanced Science, EarlyView.
Intratracheal neomycin alters pulmonary microbiota, activating the vagus nerve via lung brain‐derived neurotrophic factor/tropomyosin receptor kinase B (BDNF/TrkB) pathway, further projecting to nucleus of solitary tract (NTS), then dorsal raphe nucleus (DRN), where activated serotoninergic neurons increase brain serotonin, alleviating migraine.
Biying Liu   +7 more
wiley   +1 more source

Pancreatitis following Olanzapine Therapy: A Report of Three Cases [PDF]

open access: yes, 2007
CONTEXT: Atypical antipsychotic agents (clozapine, olanzapine) have been linked to metabolic effects and acute pancreatitis. CASE REPORT: We reviewed the inpatient and outpatient records of three patients who developed acute pancreatitis while being ...
Azar, Riad   +3 more
core   +4 more sources

Output from VIP cells of the mammalian central clock regulates daily physiological rhythms [PDF]

open access: yes, 2020
The suprachiasmatic nucleus (SCN) circadian clock is critical for optimising daily cycles in mammalian physiology and behaviour. The roles of the various SCN cell types in communicating timing information to downstream physiological systems remain ...
A Kalsbeek   +70 more
core   +1 more source

Clozapine-induced agranulocytosis [PDF]

open access: yesAnnals of Hematology, 2020
AbstractWider use of clozapine, one of the most effective antipshychotic drugs, is precluded by its propensity to cause agranulocytosis. Currently, clozapine is used for treatment-resistant schizophrenia, with mandatory blood count monitoring for the duration of treatment.
Aleksandar Mijovic, James H. MacCabe
openaire   +3 more sources

Regulation of PVT‐CeA Circuit in Deoxynivalenol‐Induced Anorexia and Aversive‐Like Emotions

open access: yesAdvanced Science, EarlyView.
The study investigates Deoxynivalenol (DON) effects on feeding and emotions, focusing on the central amygdala (CeA). Acute DON exposure reduces food intake and alters behavior, linked to CeAGABA neuron activity and PVT‐CeA connectivity. Manipulating CeAGABA neurons and using SCN10A antagonist A‐803467 alleviate DON's effects, offering potential ...
Liu‐Nan Yang   +4 more
wiley   +1 more source

The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression

open access: yesAdvanced Science, EarlyView.
LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao   +7 more
wiley   +1 more source

An in vivo biosensor for neurotransmitter release and in situ receptor activity. [PDF]

open access: yes, 2010
Tools from molecular biology, combined with in vivo optical imaging techniques, provide new mechanisms for noninvasively observing brain processes. Current approaches primarily probe cell-based variables, such as cytosolic calcium or membrane potential ...
Griesbeck, Oliver   +6 more
core   +2 more sources

Rhabdomyolysis in Clozapine Overdose [PDF]

open access: yesDrug Safety - Case Reports, 2015
Clozapine is used for decennia for the treatment of schizophrenia. Agranulocytosis, diabetic ketoacidosis, gastrointestinal hypomotility, and myocarditis are well-known adverse effects of clozapine, which are sometimes life threatening. Here we report a case of rhabdomyolysis upon an acute overdose of clozapine.A male patient, 36 years, with elevated ...
Heleen A. Crommelin   +3 more
openaire   +3 more sources

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