Results 191 to 200 of about 18,135 (204)
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ClpP: Neues Target für die Krebstherapie?

InFo Hämatologie + Onkologie, 2019
openaire   +1 more source

Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia

Cancer Cell, 2015
Etienne Coyaud   +2 more
exaly  

The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease

EMBO Molecular Medicine, 2009
Janine Kirstein   +2 more
exaly  

Vaccine comprising a recombinant S. pneumoniae ClpP protein

2011
Problem to be Solved: The present invention relates to vaccines containing recombinant CLPP proteins of streptococcus pneumoniae. In the present invention, which has demonstrated that the CLPP has been moved into the cell wall after thermal shock, a protective immunity against systemic diseases is induced at a level comparable to a level obtained when ...
openaire   +1 more source

ClpP: a new Achilles' heel in myeloma

Blood
Antonio Sacco, Aldo M. Roccaro
openaire   +1 more source

Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death

Cell Chemical Biology, 2018
Keith S Wong   +2 more
exaly  

Quantitative NMR spectroscopy of supramolecular complexes: Dynamic side pores in ClpP are important for product release

Proceedings of the National Academy of Sciences of the United States of America, 2005
Peter M Hwang   +2 more
exaly  

Vaccine comprising recombinant CLPP protein of Streptococcus pneumoniae

2011
A method for immunizing a human or animal against pneumococcal infections, comprising by administering a vaccine comprising a purified recombinant caseinolytic protease P (ClpP) protein of S. pneumoniae in an immunologically effective amount to the human or animal.
openaire   +1 more source

Reversible inhibition of the ClpP protease via an N-terminal conformational switch

Proceedings of the National Academy of Sciences of the United States of America, 2018
Siavash Vahidi   +2 more
exaly  

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