Results 61 to 70 of about 124,654 (199)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Genetic Testing Among Breast Cancer Patients in the Eastern Region of Saudi Arabia: Single-Center Experience

open access: yesJournal of Epidemiology and Global Health
Background Genetic testing for persons with a heightened likelihood of harboring a germline mutation permits early identification and appropriate management.
Ghadeer Al Ghareeb   +6 more
doaj   +1 more source

Subspace Clustering through Sub-Clusters

open access: yes, 2018
The problem of dimension reduction is of increasing importance in modern data analysis. In this paper, we consider modeling the collection of points in a high dimensional space as a union of low dimensional subspaces. In particular we propose a highly scalable sampling based algorithm that clusters the entire data via first spectral clustering of a ...
Li, Weiwei   +2 more
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Economic Integration in the System of Spatial Development of the Region

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2020
The article studies specific features of economic integration processes in the context of regional market space clustering. Methodological principles of today’s cluster systems are shown and their signs are identified with signs of heterogeneous network ...
T. N. Topoleva
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Upgrading Mechanisms of Managing Social and Economic Development of Tourism on Regional Level

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2020
Mechanisms of developing tourism on the regional level are numerous and they can be systematized by different characteristics. However, it is better to give a general view of the system of such mechanisms through classical management functions that ...
S. B. Boldyreva
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Widespread production of plant growth-promoting hormones among marine bacteria and their impacts on the growth of a marine diatom

open access: yesMicrobiome
Background Reciprocal exchanges of metabolites between phytoplankton and bacteria influence the fitness of these microorganisms which ultimately shapes the productivity of marine ecosystems.
Abeeha Khalil   +7 more
doaj   +1 more source

Clusters

open access: yesTidsskrift for Den norske legeforening, 2022
Mette Langaas, Jo Røislien
openaire   +2 more sources

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