Results 21 to 30 of about 1,772 (132)

Aspen Tension Wood Fibers Contain β-(1---> 4)-Galactans and Acidic Arabinogalactans Retained by Cellulose Microfibrils in Gelatinous Walls. [PDF]

, 2015
Contractile cell walls are found in various plant organs and tissues such as tendrils, contractile roots, and tension wood. The tension-generating mechanism is not known but is thought to involve special cell wall architecture.
Banasiak, Alicja, Chernova, Tatyana, Dupree, Paul, Gorshkova, Tatyana, Ibragimova, Nadezhda, Immerzeel, Peter, Mellerowicz, Ewa J, Mikshina, Polina, Mokshina, Natalia, Salnikov, Vadim, Tryfona, Theodora   +10 more
core   +5 more sources

Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia. [PDF]

, 2015
Bypassing tyrosine kinases responsible for Stat5a/b phosphorylation would be advantageous for therapy development for Stat5a/b-regulated cancers.
Blackmon, Shauna, Calabretta, Bruno, Cingolani, Gino, Dagvadorj, Ayush, De Dominici, Marco, Ellsworth, Elyse, Ertel, Adam, Fortina, Paolo, Gomella, Leonard G, Gu, Lei, Gupta, Shilpa, Hoang, David T., Lallas, Costas D., Leiby, Benjamin E., Liao, Zhiyong, Lokareddy, Ravi K., Mariani, Samanta A., McCue, Peter A., Nevalainen, Marja T., Njar, Vincent, Pattabiraman, Nagarajan, Purushottamachar, Puranik, Rui, Hallgeir, Trabulsi, Edouard J., Vergalli, Jenny, Xia, Guanjun   +25 more
core   +3 more sources

Proximity in chromatin : opportunities for innovations [PDF]

, 2014
Mammalian chromosomes extensively communicate with each other via long-range chromatin interactions. These interactions are mostly mediated by proteins, which work as teams to control genes in the cells.
Yammine, Samer
core   +1 more source

Elektrophysiologische Charakterisierung des isolierten circadianen Schrittmachers der Schabe Leucophaea maderae [PDF]

, 2005
Der Sitz des circadianen Schrittmachers, der das Laufverhalten der Schabe Leucophaea maderae steuert, wurde durch Läsions- und Transplantationsexperimente in der akzessorischen Medulla (aMe; Plural akzessorische Medullae, aMae) lokalisiert.
Schneider, Nils-Lasse, Stengl, Monika (Prof. Dr.)   +1 more
core   +1 more source

Failure of Y-27632 to improve the culture of adult human adipose-derived stem cells [PDF]

, 2015
Y-27632 is a well-known inhibitor of the Rho-associated coiled kinase (ROCK) and has been shown to significantly improve the culture of a variety of multipotent stem cell types.
Lamas, Nuno Jorge, Salgado, A. J., Serra, Sofia Cristina, Sousa, Nuno   +3 more
core   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, Volume 15, Issue 18, 15 May 2026.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Disrupted lipid homeostasis as a pathogenic mechanism in ABCA7‐associated Alzheimer's disease risk

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION ABCA7 (ATP binding cassette subfamily A member 7) encodes a lipid transporter associated with increasing risk for Alzheimer's disease (AD). A 44‐base pair deletion in ABCA7 (rs142076058; p.Arg578Alafs) is a strong risk factor in individuals of African ancestry (AA).
Younji Nam, Brooke A. DeRosa, Aura M. Ramirez, Biniyam A. Ayele, Patrice Whitehead‐Gay, Larry D. Adams, Charles G. Golightly, Takiyah D. Starks, Mayra Juliana Laverde‐Paz, Holly N. Cukier, Rufus Akinyemi, Fred Sarfo, Albert Akpalu, Michael L. Cuccaro, Scott M. Williams, Allison Caban‐Holt, Christiane Reitz, Jonathan L. Haines, Goldie S. Byrd, Farid Rajabli, Derek M. Dykxhoorn, Juan I. Young, Jeffery M. Vance, Margaret A. Pericak‐Vance   +23 more
wiley   +1 more source

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions

MedComm, Volume 7, Issue 3, March 2026.
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu, Rou Xue, Xiangwen Luo, Jiangnan Liao, Zongbo Zhang, Jinhai Deng, Teng Liu, Xin Li, Zhe‐Sheng Chen, Mingzhu Yin   +9 more
wiley   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh, Shubham Mahajan, Sadikalmahdi Abdella, Rehan Khan, Sanjay Garg   +4 more
wiley   +1 more source

Abstracts from the 3rd Conference on Aneuploidy and Cancer: Clinical and Experimental Aspects [PDF]

, 2017
Published ...
Abdallah, Batoul, Aldaz, C. M, Andreieva, Svitlana V, Avdieiev, Stanislav S, Bakker, Bjorn, Baklaushev, Vladimir P, Baudoin, Nicolaas C, Belderbos, Mirjam E, Belpoggi, Fiorella, Berezney, R., Berg, Anke, Berynskyy, Leonid, Bhattacharya, S., Biesterfeld, Stefan, Bloomfield, Mat, Bloomfield, Mathew, Bont, Eveline S J M, Bowden, Athel, Bowden, Athel, Bradley, Allan, Bullinger, Lars, Böcking, Alfred, Börgermann, Christof, Camps, Jordi, Cavaliere, Paola, Chekhonin, Vladimir P, Chiourea, Maria, Cimini, Daniela, Colina, Aracelli, Dephoure, Noah, Dickson, Robert C, Dietz, Josef, Digman, Michelle, Ding, H., Donnelly, N., Duesberg, Peter, Dürrbaum, M., Engers, Rainer, Fabarius, Alice, Foijer, Floris, Fritz, A., Futscher, Bernard, Gagos, Sarantis, Garbe, James C, Gisselsson, David, Gong, Xue, Grasedieck, Sarah, Graves, Jennifer A M, Guryev, Victor, Gustafsson, Hans T, Habermann, B., Halsema, Nancy, Hehlmann, Rüdiger, Heng, Henry H, Hoff, Andreas M, Horne, Steven, Huang, Xinhe, Huleyuk, Nataliya L, Hwang, Sunyoung, Jansson, Caroline, Johannessen, Bjarne, Jong, Tristan V, Karlsson, Jenny, Kazemier, Hinke G, Klose, Christian, Korets, Kateryna V, Kovaleva, Oksana A, Kruse, C., LaBarge, Mark A, Lansdorp, Peter M, Liehr, Thomas, Liu, Guo, Lothe, Ragnhild A, Løvf, Marthe, Mandrioli, Daniele, Mykytenko, Dmytro O, Nicholson, Joshua M, Page, N., Passerini, V., Perry, Melissa J, Pollack, Jonathan R, Porubsky, David, Quintanilla, Isabel, Raftopoulou, Christina, Rasnick, David, Roumelioti, Fani-Marlen, Rücker, Frank G, Schevchenko, Andrej, Sehgal, N., Silbergeld, Ellen K, Skotheim, Rolf I, Soto, Kimberly, Spierings, Diana C J, Stampfer, Martha R, Stein, G., Stein, J., Stepanenko, Aleksei A, Stojkovicz, B., Storchová, Z., Sullivan, Ciara, Sveen, Anita, SveeStrømme, Jonas M, Swoboda, Julian, Tatché, Maria C, Taudt, Aaron S, Torres, Eduardo M, Trinh, Andrew L, Tye, C., Valind, Anders, Vassetzky, Yegor S, Vecerova, J., Vincent, Mark D, Voskanyan, Astghik, Vrba, Lukas, Wakker, Karina, Xu, J., Ye, Christine J, Zhao, Sen, Zhou, Yi-Hong, Zhou, Yi-Hong   +119 more
core   +1 more source