Results 21 to 30 of about 986,129 (279)

FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelination. [PDF]

open access: yes, 2014
BackgroundFTY720 (fingolimod) is the first oral drug approved by the Food and Drug Administration for treatment of patients with the relapsing-remitting form of the human demyelinating disease multiple sclerosis.
Blanc, Caroline A   +2 more
core   +1 more source

How we deal with Staphylococcus aureus (MSSA, MRSA) central nervous system infections

open access: yesFrontiers in Bioscience-Scholar, 2022
Among central nervous system (CNS) infections (e.g., meningitis, brain abscess, ventriculitis, transverse myelitis), those caused by Staphylococcus aureus (SA) are particularly challenging both in management and treatment, with poor clinical outcomes and
Roberta Maria Antonello   +1 more
doaj   +1 more source

Therapeutic strategies and nano-drug delivery applications in management of ageing Alzheimer’s disease

open access: yesDrug Delivery, 2018
In recent years, the incidental rate of neurodegenerative disorders has increased proportionately with the aging population. Alzheimer’s disease (AD) is one of the most commonly reported neurodegenerative disorders, and it is estimated to increase by ...
Govindarajan Karthivashan   +4 more
doaj   +1 more source

Immunopathogenesis of infectious-inflammatory diseases of central nervous system

open access: yesЖурнал инфектологии, 2014
The revue includes the contemporary information about the role of resident cells of the CNS (astrocytes, microglia) in development of innate immune response against pathogen (or its products) invasion in the brain.
G. F. Zheleznikova, N. V. Skripchenko
doaj   +1 more source

An Evasion and Counter-Evasion Study in Malicious Websites Detection [PDF]

open access: yes, 2014
Malicious websites are a major cyber attack vector, and effective detection of them is an important cyber defense task. The main defense paradigm in this regard is that the defender uses some kind of machine learning algorithms to train a detection model,
Xu, Li   +3 more
core   +2 more sources

Influence of dimensionality on superconductivity in carbon nanotubes

open access: yes, 2007
We investigate the electronic instabilities in carbon nanotubes (CNs), looking for the break-down of the one dimensional Luttinger liquid regime due to the strong screening of the long-range part of the Coulomb repulsion. We show that such a breakdown is
Bellucci S   +11 more
core   +1 more source

TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death [PDF]

open access: yes, 1997
Newborn mice carrying targeted mutations in genes encoding neurotrophins or their signaling Trk receptors display severe neuronal deficits in the peripheral nervous system but not in the CNS. In this study, we show that trkB (¿/¿) mice have a significant
Alcántara Horrillo, Soledad   +5 more
core   +1 more source

Recent Advances on Extracellular Vesicles in Central Nervous System Diseases

open access: yesClinical Interventions in Aging, 2021
Tao Jin,1 Jiachen Gu,1 Zongshan Li,1 Zhongping Xu,2 Yaxing Gui1 1Department of Neurology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, People’s Republic of China; 2Washington University School of Medicine ...
Jin T, Gu J, Li Z, Xu Z, Gui Y
doaj  

Effects of tACS-Like Electrical Stimulation on On-Center Retinal Ganglion Cells: Part I

open access: yesEye and Brain, 2021
Franklin R Amthor, Christianne E Strang Department of Psychology, The University of Alabama at Birmingham, Birmingham, AL, 35294-1170, USACorrespondence: Franklin R AmthorDepartment of Psychology, The University of Alabama at Birmingham, 1300 University ...
Amthor FR, Strang CE
doaj  

Feasibility of using risk prompts to prevent falls, dehydration and pulmonary aspiration in nursing homes: a clinical study protocol

open access: yesPilot and Feasibility Studies, 2018
Background Evidence has shown a relationship between dehydration, falls, and pulmonary aspiration among older adults in nursing homes, all of which contribute to loss of independence and quality of life.
Márcia Duarte   +5 more
doaj   +1 more source

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