Results 201 to 210 of about 445,891 (294)

Elevated coagulation factor levels affect the tissue factor-threshold in thrombin generation

, 2018
Inge M. Rietveld, Mark Schreuder, Pieter H. Reitsma, Mettine H.A. Bos   +3 more
openalex   +2 more sources

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

Advanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang, Jiaming Sun, Ying Wang, Bichen Ren, Yuxin Liu, Yunhan Liu, Liang Chen, Lu Yu, Tao Dai, Li Yu, Zhihui Dong   +10 more
wiley   +1 more source

Distinct Coagulation Phenotypes and Long-Term Neurological Outcomes in Post-Cardiac Arrest Syndrome: A Latent Class Analysis of a 9-Year Single-Center Cohort. [PDF]

J Clin Med
Park SY, Oh SH, Kim HJ, Kim HJ, Lim JY.
europepmc   +1 more source

On the Degree of Platelet, Coagulation and Fibrinolysis Activation after Cerebral Infarction and Cerebral Haemorrhage and the Clinical Outcome

, 1993
J. W. J. van Wersch, Cees L. Franke
openalex   +2 more sources

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

CD163 and the FVIII/FXII ratio identified as novel biomarkers for early sepsis recognition. [PDF]

Front Med (Lausanne)
Yan N, Diao Y, Zhou S, Lu L, Chen C, Zhu B, Jia J, Liu J.   +7 more
europepmc   +1 more source

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

Advanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu, Zhongcheng Li, Qian Ren, Ziqian Lu, Yubing Zhang, Yili Guo, Ruomeng Li, Die Hu, Linglin Zhang   +8 more
wiley   +1 more source

Human missense variants in F3 impair the initiation of blood coagulation. [PDF]

Blood
Ansari SA, Brake MA, Pathak N, Flaumenhaft JT, Ludington JG, Panwar N, Turro E, Schulman S.   +7 more
europepmc   +1 more source

Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era

Advanced Science, EarlyView.
This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley   +1 more source

Emergency colonoscopy for rectal ulcer bleeding: argon plasma coagulation failure rescued by underwater snare-tip coagulation and self-assembling peptide hydrogel. [PDF]

Endoscopy
Alfarone L, Dibitetto S, Capogreco A, Massimi D, Maselli R, Hassan C, Repici A.   +6 more
europepmc   +1 more source