Results 31 to 40 of about 637,976 (296)

Platelets and neutrophil extracellular traps collaborate to promote intravascular coagulation during sepsis in mice.

open access: yesBlood, 2017
Neutrophil extracellular traps (NETs; webs of DNA coated in antimicrobial proteins) are released into the vasculature during sepsis where they contribute to host defense, but also cause tissue damage and organ dysfunction. Various components of NETs have
B. McDonald   +6 more
semanticscholar   +1 more source

Analysis of coagulation parameters in patients with COVID-19 in Shanghai, China.

open access: yesBioScience Trends, 2020
To investigate the characteristic of coagulation function in 303 patients with Coronavirus disease 2019 (COVID-19), we evaluated the correlation between coagulation function and disease status.
Y. Zou   +7 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

COVID‐19 coagulopathy: An in‐depth analysis of the coagulation system

open access: yesEuropean Journal of Haematology, 2020
Abnormal coagulation parameters have been reported in COVID‐19‐infected patients. Although the underlying mechanism of COVID‐19 coagulopathy remains unknown, it has been suggested to be a form of disseminated intravascular coagulation (DIC).
R. M. Martín-Rojas   +12 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Acute Myeloid Leukemia With NPM1 Mutation Presenting With Rapidly Progressing Hypereosinophilia

open access: yesCase Reports in Hematology
Hypereosinophilia presents a significant clinical challenge. We describe a case of severe, rapidly progressing hypereosinophilia, with the white blood cell count increasing from 40,000/μL to over 130,000/μL within days, and 70% eosinophils on ...
S. Einarsdottir   +4 more
doaj   +1 more source

Translation and Cultural Adaptation of the ISTH-Bleeding Assessment Tool to European Portuguese

open access: yesActa Médica Portuguesa
Introduction: A distinctive bleeding history is the first diagnostic stage of congenital hemorrhagic diseases. Furthermore, since it is in fact an assessment of the patient’s phenotype, it is not a (mere) complementary diagnostic method or test - it is ...
Diana Carneiro-Leão   +6 more
doaj   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Application progress of enhanced coagulation in water treatment

open access: yesRSC Advances, 2020
Water industries worldwide consider coagulation/flocculation to be one of the major treatment methods for improving the overall efficiency and cost effectiveness of water and wastewater treatment.
H. Cui   +4 more
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

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