MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
An Explanatory Model of Red Lentil Seed Coat Colour to Manage Degradation in Quality during Storage
AgronomyThis study presents an explanatory biophysical model developed and validated to simulate seed coat colour traits including CIE L*, a*, and b* changes over time for stored lentil cultivars PBA Hallmark, PBA Hurricane, PBA Bolt, and PBA Jumbo2 under ...
Bhawana Bhattarai +5 more
doaj +1 more source
Frequencies of genes for coat colour and horns in Nordic cattle breeds
Genetics Selection Evolution, 2000 Gene frequencies of coat colour and horn types were assessed in 22 Nordic cattle breeds in a project aimed at establishing genetic profiles of the breeds under study. The coat colour loci yielding information on genetic variation were: extension, agouti,
Lien Sigbjørn +7 more
doaj +1 more source
Loyalist Lieutenant Jeremiah French and His Uniform [PDF]
, 2012 There are many unique and remarkable uniforms in the collections of the Canadian War Museum, some of which go back quite far into our history. One of these, probably the oldest presently known uniform that can be assigned to a unit raised in Canada, is ...
Chartrand, René
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Altitude, latitude and climate zone as determinants of mountain hare (Lepus timidus) coat colour change. [PDF]
Ecol Evol, 2023 Stokes AW +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Seed coat colour and structure are related to the seed dormancy and overwintering ability of crop-to-wild hybrid soybean. [PDF]
AoB Plants, 2023 Zhang L +6 more
europepmc +1 more source
‘And I know damned-well what he wanted!’ Deliberate Alteration and Interpretations of Intent in Several Late Sculptures by David Smith [PDF]
, 2014 Some years after the death of David Smith (1906–1965), Clement Greenberg, then executor of his estate, made a decision to have the white painted surface stripped from five sculptures and present them as authentic works by the artist.
Mulholland, Richard
core +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source