Results 21 to 30 of about 43,643 (334)

Questioning the pros and cons of metformin treatment in diabetic peripheral neuropathy. [PDF]

J Diabetes Investig
Journal of Diabetes Investigation, Volume 16, Issue 7, Page 1151-1153, July 2025.
Mizukami H.
europepmc   +2 more sources

The Intestinal Microbiome in Dogs with Chronic Enteropathies and Cobalamin Deficiency or Normocobalaminemia—A Comparative Study

Animals, 2023
Cobalamin deficiency is a common sequela of chronic enteropathies (CE) in dogs. Studies comparing the intestinal microbiome of CE dogs with cobalamin deficiency to those that are normocobalaminemic are lacking.
Linda Toresson, Jan S. Suchodolski, Thomas Spillmann, Bruna C. Lopes, Johnathan Shih, Jörg M. Steiner, Rachel Pilla   +6 more
doaj   +1 more source

Crystal structure of an atypical cobalamin riboswitch reveals RNA structural adaptability as basis for promiscuous ligand binding

Nucleic Acids Research, 2020
Cobalamin riboswitches encompass a structurally diverse group of cis-acting, gene regulatory elements found mostly in bacterial messenger RNA and are classified into subtypes based on secondary and tertiary characteristics.
Clarence W Chan, A. Mondragón
semanticscholar   +1 more source

COBALAMIN DEFICIENCY IN THE ELDERLY

Mediterranean Journal of Hematology and Infectious Diseases, 2020
Older people are at risk for cobalamin (vitamin B12) deficiency because of a number of common disorders (e.g. autoimmune gastritis) and drugs (e.g. antacids) that may alter its absorption and utilization. The prevalence of cobalamin deficiency increases with age, resulting particularly elevated in frail and institutionalized subjects.
Marchi, Giacomo, Busti, Fabiana, Lira Zidanes, Acaynne, Vianello, Alice, Girelli, Domenico   +4 more
openaire   +6 more sources

Rapid healing of a patient with dramatic subacute combined degeneration of spinal cord: a case report [PDF]

, 2017
Background: Prevalence of cobalamin deficiency is high especially in older patients and an immediate therapy start is necessary to prevent irreversible neurological damages. Unfortunately, the diagnosis of cobalamin deficiency is difficult and at present,
Roessler, Florian C., Wolff, Stephanie
core   +1 more source

B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin

CNS Neuroscience & Therapeutics, 2019
Neurotropic B vitamins play crucial roles as coenzymes and beyond in the nervous system. Particularly vitamin B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) contribute essentially to the maintenance of a healthy nervous system.
C. Calderón-Ospina, M. O. Nava-Mesa
semanticscholar   +1 more source

The cobalamin-binding protein in zebrafish is an intermediate between the three cobalamin-binding proteins in human.

PLoS ONE, 2012
In humans, three soluble extracellular cobalamin-binding proteins; transcobalamin (TC), intrinsic factor (IF), and haptocorrin (HC), are involved in the uptake and transport of cobalamin.
Eva Greibe, Sergey Fedosov, Ebba Nexo
doaj   +1 more source

Novel pathway for corrinoid compounds production in lactobacillus [PDF]

, 2018
Vitamin B12 or cobalamin is an essential metabolite for humans, which makes it an interesting compound for many research groups that focus in different producer-strains synthesis pathways.
Font, Graciela Maria, Saavedra, Maria Lucila, Taranto, Maria Pia, Torres, Andrea Carolina, Vannini, María Verónica   +4 more
core   +2 more sources

De Novo Cobalamin Biosynthesis, Transport, and Assimilation and Cobalamin-Mediated Regulation of Methionine Biosynthesis in Mycobacterium smegmatis

Journal of Bacteriology, 2020
Alterations in cobalamin-dependent metabolism have marked the evolution of Mycobacterium tuberculosis into a human pathogen. However, the role(s) of cobalamin in mycobacterial physiology remain poorly understood.
Terry Kipkorir, Gabriel T M Mashabela, Timothy J. De Wet, A. Koch, L. Wiesner, V. Mizrahi, D. Warner   +6 more
semanticscholar   +1 more source

Utilization of Cobalamin Is Ubiquitous in Early-Branching Fungal Phyla

bioRxiv, 2020
Cobalamin is a cofactor present in essential metabolic pathways in animals and one of the water-soluble vitamins. It is a complex compound synthesized solely by prokaryotes. Cobalamin dependence is scattered across the tree of life.
M. Orłowska, Kamil Steczkiewicz, A. Muszewska   +2 more
semanticscholar   +1 more source