Potential of herbal cocktail of medicinal plant extracts against ‘big four’ snake venoms from India
Background: Venomous snake bites cause acute medical emergencies and are fatal. India accounts for large proportion of snake-bite deaths globally. Medically important ‘BIG FOUR’ snakes of India are Bungarus caeruleus (krait), Naja naja (cobra), Echis ...
Shwetha Vasudev +3 more
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Immunohistochemical investigation of neuronal injury in cerebral cortex of cobra-envenomed rats [PDF]
The immunohistochemical expression of neuron-specific enolase, NSE (a cytoplasmic glycolytic enzyme of the neurons), synaptophysin, SYN (a major membrane glycoprotein of synaptic vesicles), and Bcl-2 (anti-apoptotic protein) were determined in cerebral ...
T.R. Rahmy, I.A. Hassouna
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Differential effects of the venoms of Russell’s viper and Indian cobra on human myoblasts
Local tissue damage following snakebite envenoming remains a poorly researched area. To develop better strategies to treat snakebites, it is critical to understand the mechanisms through which venom toxins induce envenomation effects including local ...
Husain Bin Haidar +7 more
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Cobra venom factor (CVF) is the complement-activating protein in cobra venom. It is a three-chain glycoprotein with a molecular weight of 149 000 Da. In serum, CVF forms a bimolecular enzyme with the Bb subunit of factor B.
Rajendra Kumar Singh +13 more
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A peptide from Schumanniophyton-magnificum with anti-cobra venom activity
Using the chick biventer cervicis preparation as a bioassay for antivenom activity, a peptide has been isolated from the aqueous extract of the bark of Schumanniophyton magnificum.
Houghton, PJ, Osibogun, I, Bansal, Sukhi
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Mucuna pruriens Linn. seed extract pretreatment protects against cardiorespiratory and neuromuscular depressant effects of Naja sputatrix (Javan spitting cobra) venom in rats [PDF]
Mucuna pruriens has been used by native Nigerians as a prophylactic for snakebite. The protective effects of M. pruriens seed extract (MPE) were investigated against the pharmacological actions of N. sputatrix (Javan spitting cobra) venom in rats.
Fung, S.Y. +4 more
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Molecular dissection of cobra venom highlights heparinoids as an antidote for spitting cobra envenoming [PDF]
Snakebites affect about 1.8 million people annually. The current standard of care involves antibody-based antivenoms, which can be difficult to access and are generally not effective against local tissue injury, the primary cause of morbidity.
Westhorpe, Adam +39 more
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Blindness from spitting cobra venom: Case report [PDF]
Spitting cobra is the name given to some snakes of the family of Elapidae, belonging to the genus Naja or Hemachatus that have the ability to spitt heir venom (up to 3m) to blind their predators. Naja mossambica is the most answered species in Africa.The
Tapsoba, Y., Atipo-Tsiba, P. W.
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Bitis arietans (Puff adder), Naja haje (Egyptian cobra), and Naja pallida (Red spitting cobra) venoms were tested for antimicrobial activity. This evaluation employed disc diffusion and microbroth dilution techniques.
Mitchel Otieno Okumu +3 more
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The Clinical Significance of Venom Detection in Patients of Cobra Snakebite
Cobra snakebites are one of the most frequent occurrences among the poisonous snakebites. The correlation between the serum concentrations of cobra venom in the victims with the severity of systemic and local symptoms after envenoming is still awaited ...
Hung, Dong-Zong; Liau, Ming-Yi; Lin-Shiau, Shoei-Yn +1 more
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