Results 121 to 130 of about 107,745 (350)

Artificial hearing systems based on functional cochlea models

open access: yesInternational Journal of Extreme Manufacturing
The cochlea is one of the most complex organs in the human body, exhibiting a complex interplay of characteristics in acoustic, mechanical, electrical, and biological functions.
Jinke Chang   +5 more
doaj   +1 more source

Postnatal Development of Microglia-Like Cells in Mouse Cochlea

open access: yesNeural Plasticity, 2018
Microglial cells are involved in surveillance and cleaning of the central nervous system. Recently, microglial-like cells (MLC) have been found in an adult cochlea and investigated for their role in cochlear inflammation. The presence and potential roles
Penghui Chen   +6 more
doaj   +1 more source

Statistical shape modeling of the human inner ear through micro‐computed tomography imaging

open access: yesThe Anatomical Record, EarlyView.
In this study, 54 cadaveric temporal bone specimens underwent high‐resolution micro‐CT imaging. Images were semi‐automatically segmented and converted to 3D surface mesh models for morphological measurement and analysis. Statistical shape models were created for the inner ear, cochlea, and vestibular system, as well as for sex‐ and side‐based subgroups.
Carmine Spedaliere   +8 more
wiley   +1 more source

Fast Waves at the Base of the Cochlea.

open access: yesPLoS ONE, 2015
Georg von Békésy observed that the onset times of responses to brief-duration stimuli vary as a function of distance from the stapes, with basal regions starting to move earlier than apical ones.
Alberto Recio-Spinoso, William S Rhode
doaj   +1 more source

Expression of tumor necrosis factor-α and interleukin-1β genes in the cochlea and inferior colliculus in salicylate-induced tinnitus

open access: yesJournal of Neuroinflammation, 2011
Background Changes in the gene expressions for tumor necrosis factor-α (TNF-α) and/or interleukin-1β (IL-1β) during tinnitus have not been previously reported.
Chen Jin-Cherng   +4 more
doaj   +1 more source

New techniques for old bones: Morphometric and diffeomorphometric analysis of the bony labyrinth of the Reilingen and Ehringsdorf Neandertals

open access: yesThe Anatomical Record, EarlyView.
Abstract Neandertals are known to possess very distinctive traits in their bony labyrinth morphology, such as an inferiorly positioned posterior canal and a very low number of turns in the cochlea. Hence, the inner ear has been often used to assess the Neandertal status of fragmentary fossils.
Alessandro Urciuoli   +6 more
wiley   +1 more source

Altered Auditory Maturation in Fragile X Syndrome and Its Involvement in Audiogenic Seizure Susceptibility

open access: yesAutism Research, EarlyView.
ABSTRACT Auditory hypersensitivity is a prominent symptom in Fragile X syndrome (FXS), the most prevalent monogenic cause of autism and intellectual disability. FXS arises through the loss of the protein encoded by the FMR1 (Fragile X Messenger Ribonucleoprotein 1) gene, FMRP, required for normal neural circuit excitability.
Dorit Möhrle   +4 more
wiley   +1 more source

Intracochlear PLGA based implants for dexamethasone release: Challenges and solutions

open access: yesInternational Journal of Pharmaceutics: X, 2019
The effective treatment of diseases of the inner ear is currently an unmet medical need. Local controlled drug delivery to the cochlea is challenging due to the hidden location, small volume and high sensitivity of this organ.
E. Lehner   +4 more
doaj   +1 more source

The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15 [PDF]

open access: yes, 2006
Sound and acceleration are detected by hair bundles, mechanosensory structures located at the apical pole of hair cells in the inner ear. The different elements of the hair bundle, the stereocilia and a kinocilium, are interconnected by a variety of link
Ahmed, Zubair M   +14 more
core   +2 more sources

Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing

open access: yesScientific Reports, 2015
Pannexin1 (Panx1) is a gap junction gene in vertebrates whose proteins mainly function as non-junctional channels on the cell surface. Panx1 channels can release ATP under physiological conditions and play critical roles in many physiological and ...
Jin Chen   +4 more
semanticscholar   +1 more source

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