Results 121 to 130 of about 66,419 (330)
A restudy of the minute anatomy of structures in the cochlea with conclusions bearing on the solution of the problem of tone perception [PDF]
, 1907 George E. Shambaugh
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Worth the Effort: Lessons for Discovery and Care From an Unusual Case of Gorlin Syndrome
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Gorlin‐Goltz Syndrome (GGS) is a rare autosomal dominant genetic disorder encompassing a diverse range of clinical manifestations, including congenital anomalies and predisposition to cancer. Pathogenic variants in PTCH1 and SUFU account for up to 79% and 6% of cases, respectively. Currently, an estimated 15%–27% of individuals with a clinical
V. Taliercio +13 more
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Molecular Therapy: Methods & Clinical Development, 2022 Inner ear gene therapy using adeno-associated viruses (AAVs) has been successfully applied to several mouse models of hereditary hearing loss to improve their auditory function. While most inner ear gene therapy studies have focused on the mechanosensory
Kevin Isgrig +8 more
doaj
eLife, 2019 The mammalian cochlea loses its ability to regenerate new hair cells prior to the onset of hearing. In contrast, the adult vestibular system can produce new hair cells in response to damage, or by reprogramming of supporting cells with the hair cell ...
Hsin-I Jen +11 more
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Electrical Stimulation of the Human Cochlea [PDF]
, 1937 C. S. Hallpike, H. Hartridge
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American Journal of Medical Genetics Part A, EarlyView.ABSTRACT This study presents the case of a child with multiple congenital anomalies, severe hypotonia, and profound bilateral sensorineural hearing loss. Functional bioenergetic assessments showed no significant mitochondrial respiratory defects, and riboflavin (Rf) status evaluation excluded a deficiency in Rf transporters as a cause of hearing loss ...
Piero Leone +13 more
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The nature of bone conduction as shown in the electrical response of the cochlea [PDF]
, 1937 Ernest Glen Wever, Charles W. Bray
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Early synapsids neurosensory diversity revealed by CT and synchrotron scanning
The Anatomical Record, EarlyView.Abstract Non‐mammaliaform synapsids (NMS) represent the closest relatives of today's mammals among the early amniotes. Exploring their brain and nervous system is key to understanding how mammals evolved. Here, using CT and Synchrotron scanning, we document for the first time three extreme cases of neurosensory and behavioral adaptations that probe ...
J. Benoit +6 more
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Localization of Response in the Cochlea as Determined by Electrical Recording [PDF]
, 1941 E. H. Kemp, Parker Johnson
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Predicting ecology and hearing sensitivities in Parapontoporia—An extinct long‐snouted dolphin
The Anatomical Record, EarlyView.Abstract Analyses of the cetacean (whale and dolphin) inner ear provide glimpses into the ecology and evolution of extinct and extant groups. The paleoecology of the long‐snouted odontocete (toothed whale) group, Parapontoporia, is primarily marine with its depositional context also suggesting freshwater tolerance.
Joyce Sanks, Rachel Racicot
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