c-Myb protects cochlear hair cells from cisplatin-induced damage via the PI3K/Akt signaling pathway
Cell Death Discovery, 2022 The transcription factor c-Myb is vital for cell survival, proliferation, differentiation, and apoptosis. We have previously reported that c-Myb knockdown exacerbates neomycin-induced damage to cochlea cells. However, the function and regulation of c-Myb
Chuan Bu +7 more
doaj +1 more source
Association between obstructive apnea syndrome during sleep and damages to anterior labyrinth: Our experience [PDF]
, 2019 The obstructive sleep apnea syndrome is a chronic condition characterized by frequent episodes of collapse of the upper airways during sleep. It can be considered a multisystem disease.
Gallina, S. +3 more
core +1 more source
Hearing Loss After Activation of Hearing Preservation Cochlear Implants Might Be Related to Afferent Cochlear Innervation Injury [PDF]
Otology & Neurotology, 2015 Characterize hearing loss (HL) after hearing preservation cochlear implantation and determine the association between high charge electrical stimulation (ES) and late loss of acoustic hearing.A retrospective cohort analysis of all hearing preservation implantees at our center (n = 42) assayed HL as a function of maximum charge.
Jonathan C, Kopelovich +6 more
openaire +2 more sources
CellsThe cochlea is susceptible to damage from ototoxic agents such as cisplatin, yet the mechanisms underlying cochlear injury remain incompletely understood.
Bin Zeng +6 more
doaj +1 more source
Middle East Current Psychiatry, 2022 Background There is a greater incidence of mental health problems among children with hearing impairment compared to controls. A high proportion of children with hearing impairment experience delays in understanding, recognizing, and using emotional ...
A. Ghaly +4 more
doaj +1 more source
Towards a Reconfigurable Sense-and-Stimulate Neural Interface Generating Biphasic Interleaved Stimulus [PDF]
, 2007 Published ...
Constandinou, T G +4 more
core +1 more source
Ethical Precision in Nanoscale Brain Interfacing
Advanced Science, EarlyView.As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley +1 more source
Contralateral inhibition of click- and chirp-evoked human compound action potentials [PDF]
, 2017 Cochlear outer hair cells (OHC) receive direct efferent feedback from the caudal auditory brainstem via the medial olivocochlear (MOC) bundle. This circuit provides the neural substrate for the MOC reflex, which inhibits cochlear amplifier gain and is ...
Cone, Barbara K +2 more
core +2 more sources
Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies
Animal Models and Experimental Medicine, EarlyView.This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang +4 more
wiley +1 more source
The blood labyrinthine barrier in the human normal and Meniere's disease macula utricle. [PDF]
, 2017 The ultrastructural organization of the blood labyrinthine barrier (BLB) was investigated in the human vestibular endorgan, the utricular macula, using postmortem specimens from individuals with documented normal auditory and vestibular function and ...
Ishiyama, Akira +4 more
core +2 more sources