Trimethyltin ototoxicity: evidence for a cochlear site of injury [PDF]
Hearing Research, 1986 The environmental contaminant, trimethyltin (TMT), produces a profound elevation in tone intensity necessary to inhibit the acoustic startle reflex in laboratory animals which recovers over a prolonged period except at very high frequencies. The recovery that is observed does not begin until 3 to 5 weeks after a single acute administration depending ...
Fechter, Laurence D. +2 more
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Systemic lupus erythematosus and hearing disorders: literature review and meta-analysis of clinical and temporal bone findings [PDF]
, 2017 Objective: This literature review and meta-analysis was performed to evaluate the correlations among hearing and vestibular clinical symptoms, temporal bone findings, and pathological mechanisms in patients with systemic lupus erythematosus (SLE).
DI STADIO, Arianna, Ralli, Massimo
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Transforming growth factor β1 inhibition protects from noise-induced hearing loss
Frontiers in Aging Neuroscience, 2015 Excessive exposure to noise damages the principal cochlear structures leading to hearing impairment. Inflammatory and immune responses are central mechanisms in cochlear defensive response to noise but, if unregulated, they contribute to inner ear damage
Silvia eMurillo-Cuesta +19 more
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PTEN inhibitor bisperoxovanadium protects against noise-induced hearing loss
Neural Regeneration Research, 2023 Studies have shown that phosphatase and tensin homolog deleted on chromosome ten (PTEN) participates in the regulation of cochlear hair cell survival. Bisperoxovanadium protects against neurodegeneration by inhibiting PTEN expression.
Bei Fan +9 more
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Evaluation of hearing and cochlear function by audiometric testing in patients with hyperemesis gravidarum [PDF]
, 2015 INTRODUCTION: The aim of this study was to investigate cochlear functions in patients with hyperemesis gravidarum (HG).METHODS: Twenty-nine HG patients (58 ears) and 31 healthy control subjects (62 ears) were included.
Demirtas, Ömer +5 more
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Interleukin-10 Attenuates Hypochlorous Acid-Mediated Cytotoxicity to HEI-OC1 Cochlear Cells
Frontiers in Cellular Neuroscience, 2017 Inflammatory reaction plays a crucial role in the pathophysiology of acquired hearing loss such as ototoxicity and labyrinthitis. In our earlier work, we showed the pivotal role of otic fibrocytes in cochlear inflammation and the critical involvement of ...
Martin Mwangi +6 more
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Complications of cochlear implantation surgery in Zagazig University Hospitals
The Egyptian Journal of Otolaryngology, 2021 Background Cochlear implantation (CI) has been established worldwide as the surgical treatment for individuals with bilateral severe to profound hearing loss.
Alaa Eldin M. Elfeky +4 more
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Frontiers in Cellular Neuroscience, 2019 Noise induces a broad spectrum of pathological injuries to the cochlea, reflecting both mechanical damage to the delicate architecture of the structures of the organ of Corti and metabolic damage within the organ of Corti and lateral wall tissues. Unlike
Eric C. Bielefeld +2 more
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Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity [PDF]
, 2017 Cisplatin-induced ototoxicity is one of the major factors limiting cisplatin chemotherapy. Ototoxicity results from damage to outer hair cells (OHCs) and other regions of the cochlea.
Bhatta, Puspanjali +12 more
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Subtotal petrosectomy and cerebrospinal fluid leakage in unilateral anacusis [PDF]
, 2014 Objective This study presents a group of patients experiencing recurrent cerebrospinal fluid (CSF) leakage associated with ipsilateral anacusis who underwent subtotal petrosectomies with the goal of stopping the CSF leak and preventing meningitis ...
Iannella, Giannicola, Magliulo, Giuseppe
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