Results 21 to 30 of about 25,857 (229)

Sox2 overexpression alleviates noise-induced hearing loss by inhibiting inflammation-related hair cell apoptosis

Journal of Neuroinflammation, 2022
Background The transcription factor Sox2 plays important roles in the developmental processes of multiple organs and tissues. However, whether Sox2 can protect mature or terminally differentiated cells against injury is still unknown.
Diyan Chen, Gaogan Jia, Yanping Zhang, Huanyu Mao, Liping Zhao, Wenyan Li, Yan Chen, Yusu Ni   +7 more
doaj   +1 more source

Mechanisms of sensorineural cell damage, death and survival in the cochlea. [PDF]

, 2015
The majority of acquired hearing loss, including presbycusis, is caused by irreversible damage to the sensorineural tissues of the cochlea. This article reviews the intracellular mechanisms that contribute to sensorineural damage in the cochlea, as well ...
Ryan, Allen F, Wong, Ann CY
core   +1 more source

Assembly of the Auditory Circuitry by a Hox Genetic Network in the Mouse Brainstem [PDF]

, 2013
Rhombomeres (r) contribute to brainstem auditory nuclei during development. Hox genes are determinants of rhombomere-derived fate and neuronal connectivity.
Andolfi, G., Avallone, B., Di Bonito, M., Franze, A. M., Mancuso, M., Narita, Y., Puelles, L., Rijli, F. M., Sequino, L., Studer, M.   +9 more
core   +5 more sources

The endocannabinoid/cannabinoid receptor 2 system protects against cisplatin-induced hearing loss [PDF]

, 2018
Previous studies have demonstrated the presence of cannabinoid 2 receptor (CB2R) in the rat cochlea which was induced by cisplatin. In an organ of Corti-derived cell culture model, it was also shown that an agonist of the CB2R protected these cells ...
Asmita Dhukhwa, Debashree Mukherjea, Kelly Sheehan, Leonard P. Rybak, Leonard P. Rybak, Sandeep Sheth, Sumana Ghosh, Vickram Ramkumar, Vikrant Borse   +8 more
core   +4 more sources

Inhibition of the Adenosine A_2A Receptor Mitigates Excitotoxic Injury in Organotypic Tissue Cultures of the Rat Cochlea

Cells, 2019
The primary loss of cochlear glutamatergic afferent nerve synapses due to noise or ageing (cochlear neuropathy) often presents as difficulties in speech discrimination in noisy conditions (hidden hearing loss (HHL)).
Belinda RX Han, Shelly CY Lin, Kristan Espinosa, Peter R Thorne, Srdjan M Vlajkovic   +4 more
doaj   +1 more source

Impulse noise injury prediction based on the cochlear energy [PDF]

Hearing Research, 2016
The current impulse noise criteria for the protection against impulse noise injury do not incorporate an objective measure of hearing protection. A new biomechanically-based model has been developed based on improvement of the Auditory Hazard Assessment Algorithm for the Human (AHAAH) using the integrated cochlear energy (ICE) as the damage risk ...
Brissi, Zagadou, Philemon, Chan, Kevin, Ho, David, Shelley   +3 more
openaire   +2 more sources

The role of external broadcasting in a closed political system [PDF]

, 2011
This article investigates the role and impact of external broadcasting (radio and television) on a closed political system, through the example of the two post-war German states: the West German Federal Republic of Germany (FRG) and the East German ...
Andreas Scheu, Browne DR, Castells M., Corbin J., DeFleur ML, Der Spiegel, Hafez K., Hahn O., Hesse KR, Hopkins M., Hyman HH, Infratest, Infratest, Infratest, Infratest, Jansen M., Lindlof T., McQuail D., Merritt AJ, Merritt AJ, Meyen M., Michael Meyen, Parta RE, Perse EM   +23 more
core   +2 more sources

Active and Adequate Exposure of the Facial Nerve and Chorda Tympani Nerve to Improve the Safety of Cochlear Implantation

Ear, Nose & Throat Journal, 2021
Background: The posterior tympanum approach of cochlear implantation is easy to damage the facial nerve and cord tympanic nerve. Therefore, we need to improve the safety of cochlear implantation.
Ling Lu MM, Maohua Wang MM, Jianfei Dong MM, Chuanyao Lin BM, Chenjie Yu MD, Xiaoyun Qian MD, Xia Gao MD   +6 more
doaj   +1 more source

Modeling the Measurements of Cochlear Microcirculation and Hearing Function after Loud Noise [PDF]

, 2011
Objective: Recent findings support the crucial role of microcirculatory disturbance and ischemia for hearing impairment especially after noise-induced hearing loss (NIHL).
Attanasio G, Baker M, Bernhard Olzowy, Canis M, Fraenkel R, Fritz Ihler, Fujioka M, Klyscz T, Lamm K, Le Prell CG, Markus Suckfuell, Martin Canis, Nakai Y, Nuttall AL, Nuttall AL, Nuttall AL, Ohinata Y, Ohlemiller KK, Okamoto A, Okamoto A, Perlman HB, Prazma J, Quirk WS, Scheibe F, Scherer EQ, Scherer EQ, Sebastian Strieth, Seidman MD, Thorne PR, Wangemann P, Warangkana Arpornchayanon, Weille FL, Yamane H, Zeintl H   +33 more
core   +1 more source

Glucocorticoid Treatment for Cochlear Ischemic and Acoustic Injuries

Nippon Jibiinkoka Gakkai Kaiho, 2010
The effect of glucocorticoids on sensorineural hearing loss of sudden onset remains to be controversial although glucocorticoids have been used for treatment of sudden sensorineural hearing loss. We review recent findings about the effect of glucocorticoids on cochlear ischemic and acoustic injuries obtained from animal experiments.
Keiji, Tabuchi, Akira, Hara
openaire   +3 more sources