Results 11 to 20 of about 25,857 (229)
Long‐term cochlear implantation outcomes in patients following head injury [PDF]
Laryngoscope Investigative Otolaryngology, 2020 Objective In cases of a severe to profound sensorineural hearing loss following head injury, the cochlear implant (CI) is the primary option for auditory rehabilitation.
Rory J. Lubner +8 more
doaj +4 more sources
Toll-like receptor 4 modulates the cochlear immune response to acoustic injury [PDF]
Cell Death and Disease, 2016 AbstractAcoustic overstimulation traumatizes the cochlea, resulting in auditory dysfunction. As a consequence of acoustic injury, the immune system in the cochlea is activated, leading to the production of inflammatory mediators and the infiltration of immune cells.
Vethanayagam, R R +3 more
exaly +3 more sources
meningitis following head injury after cochlear implantation: A case report
European Journal of Inflammation, 2020 Bacterial meningitis is a rare event in children with cochlear implants. A 7-year-old child who underwent cochlear implantation (CI) for the right ear 6 years ago was admitted to our hospital with the chief complaint of intermittent fever and headache ...
Zhanfeng Yan +7 more
doaj +2 more sources
Pravastatin Administration Alleviates Kanamycin-Induced Cochlear Injury and Hearing Loss. [PDF]
Int J Mol Sci, 2022 The effect of statins on aminoglycoside-induced ototoxicity is controversial. This study aimed to explore the role of pravastatin (PV) in kanamycin-induced hearing loss in rats. Adult rats were intraperitoneally treated with 20 mg/kg/day of kanamycin (KM) for 10 days.
Lee CH, Jeon J, Lee SM, Kim SY.
europepmc +3 more sources
Transcriptional response to mild therapeutic hypothermia in noise-induced cochlear injury. [PDF]
Front Neurosci, 2023 IntroductionPrevention or treatment for acoustic injury has been met with many translational challenges, resulting in the absence of FDA-approved interventions. Localized hypothermia following noise exposure mitigates acute cochlear injury and may serve as a potential avenue for therapeutic approaches.
Rincon Sabatino S +5 more
europepmc +4 more sources
Purinergic Signaling and Cochlear Injury-Targeting the Immune System? [PDF]
Int J Mol Sci, 2019 Hearing impairment is the most common sensory deficit, affecting more than 400 million people worldwide. Sensorineural hearing losses currently lack any specific or efficient pharmacotherapy largely due to the insufficient knowledge of the pathomechanism. Purinergic signaling plays a substantial role in cochlear (patho)physiology.
Köles L +3 more
europepmc +5 more sources
Evaluation of hidden hearing loss in normal-hearing firearm users
Frontiers in Neuroscience, 2022 Some noise exposures resulting in temporary threshold shift (TTS) result in cochlear synaptopathy. The purpose of this retrospective study was to evaluate a human population that might be at risk for noise-induced cochlear synaptopathy (i.e., “hidden ...
Sarah K. Grinn, Colleen G. Le Prell
doaj +1 more source
Adenosine amine congener mitigates noise-induced cochlear injury [PDF]
Purinergic Signalling, 2010 Hearing loss from noise exposure is a leading occupational disease, with up to 5% of the population at risk world-wide. Here, we present a novel purine-based pharmacological intervention that can ameliorate noise-induced cochlear injury. Wistar rats were exposed to narrow-band noise (8-12 kHz, 110 dB SPL, 2-24 h) to induce cochlear damage and permanent
Srdjan M, Vlajkovic +6 more
openaire +2 more sources
Chronic suppurative otitis media causes macrophage-associated sensorineural hearing loss
Journal of Neuroinflammation, 2022 Background Chronic suppurative otitis media (CSOM) is the most common cause of permanent hearing loss in children in the developing world. A large component of the permanent hearing loss is sensory in nature and our understanding of the mechanism of this
Anping Xia +9 more
doaj +1 more source
Journal of Otology, 2022 Preservation of low-frequency residual hearing is very important for combined electro-acoustic stimulation after cochlear implantation. However, in clinical practice, loss of low-frequency residual hearing often occurs after cochlear implantation and its
Juanjuan Gao, Haijin Yi
doaj +1 more source