Results 71 to 80 of about 825,232 (363)

Neuro-electronic technology in medicine and beyond [PDF]

, 2000
This dissertation looks at the technology and social issues involved with interfacing electronics directly to the human nervous system, in particular the methods for both reading and stimulating nerves.
Ward, Jamie A
core  

A ratchet mechanism for amplification in low-frequency mammalian hearing

, 2010
The sensitivity and frequency selectivity of hearing result from tuned amplification by an active process in the mechanoreceptive hair cells. In most vertebrates the active process stems from the active motility of hair bundles.
A. J. Hudspeth, Ashmore, Chan, Cooper, Cooper, Dallos, Dong, Evans, Gummer, Housley, Kennedy, Khanna, Kiang, Mammano, Martin, Mellado Lagarde, Naidu, Nuttall, Robles, Ruggero, Santos-Sacchi, Sziklai, T. Reichenbach, Ulfendahl, Zheng, Zinn, Zwislocki   +26 more
core   +2 more sources

The Impact of Age and Duration of Cochlear Implant in a Congenital Deaf Population: An ERP Study [PDF]

, 2016
Objective: It is well known that patients with Cochlear Implant (CI) have a large inter-individual variability in linguistic and auditory performances. This can be related to individual auditory processing abilities and integrity of auditory system from ...
Ermani, Mario, Gheller, Flavia, Ghiselli, Sara, Martini, Alessandro, Rampazzo, Patrizia, Trevisi, Patrizia   +5 more
core   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

A case of cochlear-facial dehiscence revealed after bilateral cochlear implants

Radiology Case Reports
The cochlear implant is an implanted auditory prosthesis that can restore severe and profound hearing loss. About 20% of patients with congenital sensorineural hearing loss have a malformation of the inner ear.
Chiara Perazzini, Luce Compagnone, Pascal Chabrot, Luis Boyer, Mathilde Puechmaille, Thierry Mom   +5 more
doaj   +1 more source

Classification and Current Management of Inner Ear Malformations

Balkan Medical Journal, 2017
Morphologically congenital sensorineural hearing loss can be investigated under two categories. Majority of the congenital hearing loss (80%) are membranous malformations. Here the pathology involves inner ear hair cells.
Levent Sennaroğlu, Münir Demir Bajin
doaj   +1 more source

Gut–Metabolome–Proteome Interactions in Age‐Related Hearing Loss: Insights from Fecal Microbiota Transplantation and Multi‐Omics Analyses

Advanced Science, EarlyView.
Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang, Ziwen Gao, Hui Huang, Chanyuan Zhang, Yiquan Tang, Qianhui Qu, Huabin Li, Jing Ke, Zhiji Chen, Menglong Feng, Hu Zhou, Yilai Shu, Wei Yuan   +12 more
wiley   +1 more source

Complications of cochlear implantation surgery in Zagazig University Hospitals

The Egyptian Journal of Otolaryngology, 2021
Background Cochlear implantation (CI) has been established worldwide as the surgical treatment for individuals with bilateral severe to profound hearing loss.
Alaa Eldin M. Elfeky, Adly A. Tantawy, Asmaa M. Ibrahim, Ibrahim M. Saber, Said Abdel-Monem   +4 more
doaj   +1 more source

Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age-Related Hearing Loss via Enhancing Schwann Cell Migration. [PDF]

Aging Cell
The illustration indicates that increased BST2 expression in Schwann cells leads to cochlear nerve demyelination, accelerating hearing loss in ARHL. The upregulation of BST2 reduces POU6F1 expression by activating the NF‐κB pathway, which impairs MPZ transcription and Schwann cell migration, ultimately contributing to neural demyelination in ARHL ...
Liu M, Li Q, Cao H, Yin H, Yang J, Liu T, Wang J, Zhao L, Wang B.   +8 more
europepmc   +2 more sources

Cidea Targeting Protects Cochlear Hair Cells and Hearing Function From Drug‐ and Noise‐Induced Damage

Advanced Science, EarlyView.
Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang, Ruiying Qiang, Yuan Zhang, Jinxian Wan, Chen Tao, Ying Dong, Xujun Tang, Li Xu, Hairong Xiao, Yanqin Lin, Wei Tong, Ying Ma, Yongming Wang, Peng Li, Renjie Chai   +14 more
wiley   +1 more source