A Case of Perilymphatic Fistula with Inner Ear Anomaly Diagnosed Preoperatively by the Cochlin-Tomoprotein Detection Test [PDF]
Case Reports in Otolaryngology, 2020 We present a case of perilymphatic fistula (PLF) with inner ear anomalies having sudden, progressive sensorineural hearing loss and describe the fistula repair surgeries.
Kohei Yamahara +2 more
exaly +9 more sources
Objective Assessment of Perilymphatic Fistula in Cases of Postoperative Vertigo after Cochlear Implantation by Cochlin Tomoprotein (CTP) [PDF]
Brain Sciences, 2023 Objective: Vertigo is a quite frequent complication after cochlear implantation. Perilymphatic fistula (PLF) is assumed to be one cause of this problem. Cochlin tomoprotein (CTP) is a newly introduced marker for PLF.
Ingo Todt, Tetsuo Ikezono
exaly +8 more sources
The diagnostic performance of a novel ELISA for human CTP (Cochlin-tomoprotein) to detect perilymph leakage [PDF]
PLoS ONE, 2018 Perilymphatic fistula is defined as an abnormal communication between the perilymph-filled space and the middle ear, or cranial spaces. The manifestations include a broad spectrum of neuro-otological symptoms such as hearing loss, vertigo/dizziness ...
Shin-Ichi Usami +2 more
exaly +7 more sources
Vestibule-Middle Ear Dehiscence Tested With Perilymph-Specific Protein Cochlin-Tomoprotein (CTP) Detection Test [PDF]
Frontiers in Neurology, 2019 An 8-year-old boy was referred to the ENT department for further evaluation of right-sided conductive hearing loss. A small cyst anterior to the oval window and fixation of the stapes footplate were observed during an exploratory tympanotomy.
Takeshi Fujita +2 more
exaly +9 more sources
Secretion of cochlin-tomoprotein (LCCL) in the middle ear following acute tympanic injury: implications for perilymph fistula diagnosis [PDF]
Frontiers in NeurologyIntroductionCochlin is the most abundant protein in the inner ear. The cleaved N-terminal domain of cochlin, known as LCCL and referred to as CTP (cochlin tomoprotein) in clinical biomarker usage, is a perilymph-specific protein and is widely used as a ...
Seonghoon Bae +2 more
exaly +8 more sources
MRI-Based Inner Ear Assessment and Cochlin Tomoprotein-Based Evaluation of Perilymphatic Fistula in Patients with Sudden Hearing Loss [PDF]
Brain SciencesObjectives: To study the correlation between positive cochlin tomoprotein testing (CTP), magnetic resonance (MR) imaging, and the auditory and vestibular function amongst patients with sudden hearing loss. Study Design: Prospective case series.
Ingo Todt +2 more
exaly +7 more sources
Assessing the efficacy of perilymphatic fistula repair surgery in alleviating vestibular symptoms and associated auditory impairments [PDF]
Frontiers in Neurology, 2023 Perilymph Fistula (PLF), abnormal communication between the fluid-filled space of the inner ear and the air-filled space of the middle ear, is a significant cause of vestibular and auditory symptoms. This is a retrospective study of 22 cases treated with
Han Matsuda +2 more
doaj +2 more sources
Prevalence of perilymphatic fistula in patients with sudden-onset sensorineural hearing loss as diagnosed by Cochlin-tomoprotein (CTP) biomarker detection: its association with age, hearing severity, and treatment outcomes. [PDF]
Eur Arch Otorhinolaryngol, 2023 Abstract Purpose To determine the prevalence of perilymphatic fistula (PLF) in sudden-onset sensorineural hearing loss (SSNHL) patients by employing the Cochlin-tomoprotein (CTP) detection test, a specific diagnostic marker for perilymph.
Sasaki A +7 more
europepmc +3 more sources
Congenital Membranous Stapes Footplate Producing Episodic Pressure-Induced Perilymphatic Fistula Symptoms [PDF]
Frontiers in Neurology, 2020 Introduction: Recent third window syndrome studies have revealed that the intact bony labyrinth and differences in the stiffness of the oval and round windows are essential for proper cochlear and vestibular function.
Han Matsuda +9 more
doaj +2 more sources
[The diagnostic value of cochlin-tomoprotein in perilymphatic fistula]. [PDF]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 2020 Perilymphatic fistula（PLF） is defined as an abnormal communication between the fluid（perilymph） -filled space of the inner ear and the air-filled space of the middle ear and mastoid, or cranial spaces. At present the diagnostic criteria for perilymphatic fistula is the fistula hole confirmed by the microscope and endoscope between the middle ear and ...
Xiong X, Yu J, Sun Y.
europepmc +3 more sources