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Procedia Chemistry, 2014 AbstractCocrystals are very interesting and useful product. In this paper the main information about cocrystals is presented. It is shown that cocrystals are solid substances, which consist of few components mixed together. There are a lot of ways of cocrystals production and application.
Korotkova, Elena Ivanovna +1 more
exaly +4 more sources
Bioavailability of indomethacin-saccharin cocrystals
Journal of Pharmacy and Pharmacology, 2010 Abstract Objectives Pharmaceutical cocrystals are new solid forms with physicochemical properties that appear promising for drug product development. However, the in-vivo bioavailability of cocrystals has rarely been addressed.
Min-Soo Kim +2 more
exaly +4 more sources
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Cocrystal: A Review on the Design and Preparation of Pharmaceutical Cocrystals
Asian Journal of Research in Pharmaceutical Sciences, 2023The majority of the active pharmaceutical components have issues with poor solubility, bioavailability, chemical stability, and moisture absorption. Pharmaceutical crystals are a reliable way to change the aforementioned physicochemical properties of drugs without changing their pharmacological behaviour.
Tanmay Jit +4 more
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Pharmaceutical cocrystals: An overview
International Journal of Pharmaceutics, 2011Pharmaceutical cocrystals are emerging as a new class of solid drugs with improved physicochemical properties, which has attracted increased interests from both industrial and academic researchers. In this paper a brief and systematic overview of pharmaceutical cocrystals is provided, with particular focus on cocrystal design strategies, formation ...
Qiao, N. +5 more
openaire +3 more sources
Color-Tunable Upconversion-Emission Switch Based on Cocrystal-to-Cocrystal Transformation
Journal of the American Chemical Society, 2023Cocrystal engineering, involving the assembly of two or more components into a highly ordered solid-state superstructure, has emerged as a popular strategy for tuning the photophysical properties of crystalline materials. The reversible co-assembly and disassembly of multicomponent cocrystals and their reciprocal transformation in the solid state ...
Yu Wang +6 more
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Nutraceutical cocrystals: utilizing pterostilbene as a cocrystal former
CrystEngComm, 2010The nutraceutical compound pterostilbene is investigated for its propensity to form cocrystalline materials with active pharmaceutical ingredients. Three cocrystals of a 1 : 1 stoichiometric molar ratio of pterostilbene with caffeine (two polymorphs, Form I and Form II) and carbamazepine were prepared and characterized by crystallographic (XRPD, single-
Nate Schultheiss +2 more
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Development and Evolution of Energetic Cocrystals
Accounts of Chemical Research, 2021In spite of the importance of energetic materials to a broad range of military (munitions, missiles) and civilian (mining, space exploration) technologies, the introduction of new chemical entities in the field occurs at a very slow pace. This situation is understandable considering the stringent requirements for cost and safety that must be met for ...
Jonathan C. Bennion, Adam J. Matzger
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Chem. Commun., 2006
The reaction between pairs of enantiomeric cocrystals involving caffeine or theophylline and a chiral cocrystal former has been investigated by liquid-assisted grinding: we demonstrate two different outcomes for such cocrystal-cocrystal reactions.
Friščić, Tomislav +4 more
openaire +3 more sources
The reaction between pairs of enantiomeric cocrystals involving caffeine or theophylline and a chiral cocrystal former has been investigated by liquid-assisted grinding: we demonstrate two different outcomes for such cocrystal-cocrystal reactions.
Friščić, Tomislav +4 more
openaire +3 more sources
Stability screening of pharmaceutical cocrystals
Pharmaceutical Development and Technology, 2021An efficient protocol for assessing both the chemical and physical stability of cocrystalline forms of active pharmaceutical ingredients (APIs) is proposed. In this protocol, the cocrystalline material is used to prepare two standard formulations, mimicking wet granulations, to make low-dose tablets.
Kenneth C, Waterman +5 more
openaire +2 more sources