Results 41 to 50 of about 5,297,063 (270)

ATP‐Mediated Bidirectional Communication Between Natural and Artificial Cells for Controlled Bioreactions

Advanced Functional Materials, EarlyView.
Establishment of bidirectional communication behavior between natural and artificial cells. The first type of communication from natural dendritic cells to artificial polymeric cells was achieved via ATP release after cell lysis. The released ATP was taken up via gated UV‐controlled permeability increase of the polymeric membrane for performing ...
Ilona Kalte, Tsvetomir Ivanov, Leonhard Seufert, Shoupeng Cao, Lucas Caire da Silva, Volker Mailänder, Katharina Landfester   +6 more
wiley   +1 more source

Coculture of tumor organoids with pathogenic microorganisms: a novel system to mimic in vivo pathogenic infection

Frontiers in Cellular and Infection Microbiology
Since the early 20th century, there has been extensive discussion on the intricate relationship between pathogenic infection and tumors. However, most studies on host-pathogen interactions are performed based on the in-vitro culture, immortalized cell ...
Xue Zhang, Shulan Sun, Siqi Cheng, Junze Dai, Furong Du, Jingrui Wang, Dan Wei, Yichao Yan, Yefu Liu   +8 more
doaj   +1 more source

Overexpression of HOXB4 Promotes Protection of Bone Marrow Mesenchymal Stem Cells Against Lipopolysaccharide-Induced Acute Lung Injury Partially Through the Activation of Wnt/β-Catenin Signaling

Journal of Inflammation Research, 2021
Shan Lin,1,2 Qingui Chen,1,2 Lishan Zhang,1,2 Shanhui Ge,1,2 Yuling Luo,1,2 Wanmei He,1,2 Caixia Xu,3 Mian Zeng1,2 1Department of Medical Intensive Care Unit, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510080, People’s ...
Lin S, Chen Q, Zhang L, Ge S, Luo Y, He W, Xu C, Zeng M   +7 more
doaj  

Modeling nervous system tumors with human stem cells and organoids

Cell Regeneration, 2023
Nervous system cancers are the 10th leading cause of death worldwide, many of which are difficult to diagnose and exhibit varying degrees of treatment resistance.
Jie Duan, Yuan Wang
doaj   +1 more source

Functional changes of cocultured hepatocyte sheets subjected to continuous liver regeneration stimulation in cDNA-uPA/SCID mouse: Differences in transplantation sites

Regenerative Therapy, 2021
Aim: The formation of a secondary liver is expected in ectopic transplants in liver therapy. It is reported that the transplantation of hepatocyte sheets constitutes one of the techniques used to form a secondary liver.
Daisuke Miyamoto, Yusuke Sakai, Yu Huang, Chihiro Yamasaki, Chise Tateno, Hideko Hasegawa, Tomomi Murai, Takanobu Hara, Tomohiko Adachi, Akihiko Soyama, Masaaki Hidaka, Shinichiro Ito, Kengo Kanetaka, Susumu Eguchi   +13 more
doaj   +1 more source

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

Advanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng, TzuChun Chung, Katpady Akhil Tantry, Siyu Wu, Jing Tian, Yunqi Cui, Lanyu Li, Yongzan Zhou, Zhilei Zhang, Zhe Su, Gaili Cao, Kun‐Wei Yeh, Ruipeng Li, Xianghui Xiao, Adam F. G. Leontowich, Yuan‐Yu Hsueh, Zhao Pan, Kam C. Tam, Badri Narayanan, Song Li, Yimin. A. Wu   +20 more
wiley   +1 more source

Additive Manufacturing of Biopolymers for Tissue Engineering and Regenerative Medicine: An Overview, Potential Applications, Advancements, and Trends

International Journal of Polymer Science, 2021
As a technique of producing fabric engineering scaffolds, three-dimensional (3D) printing has tremendous possibilities. 3D printing applications are restricted to a wide range of biomaterials in the field of regenerative medicine and tissue engineering ...
Dhinakaran Veeman, M. Swapna Sai, P. Sureshkumar, T. Jagadeesha, L. Natrayan, M. Ravichandran, Wubishet Degife Mammo   +6 more
doaj   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Protocols for EC/NSC coculture.

, 2014
(A) Schematic description of the protocols for monoculture and coculture of D3 human cerebral microvascular endothelial cells (hCMECs) and STROC05 human neural stem cells (hNSCs). (B) 1.
Pierre-Olivier Couraud (104144), Michel Modo (229135), John D. Sinden (626010), Chung-Hsing Chou (626009)   +3 more
core   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source