Results 51 to 60 of about 5,297,063 (270)

Novel Porcine Retina Cultivation Techniques Provide Improved Photoreceptor Preservation

open access: yesFrontiers in Neuroscience, 2020
Age-related macular degeneration (AMD) is the leading cause of blindness in industrialized countries among people over 60 years. It has multiple triggers and risk factors, but despite intense research efforts, its pathomechanisms are currently not ...
Natalie Wagner   +7 more
doaj   +1 more source

A Hybrid Bioprinting–Microfabrication Approach to Controllable Multitype Spheroid Arrays for Modeling Tumor Heterogeneity

open access: yesAdvanced Healthcare Materials, EarlyView.
This work introduces a “cancer‐in‐a‐well” technology that recreates tumor heterogeneity in vitro using multitype spheroid arrays. Combining bioprinting/microdispensing with microstructured culture devices, the system improves drug screening and modeling of tumor complexity.
Simone Bonetti   +10 more
wiley   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

open access: yesAdvanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk   +11 more
wiley   +1 more source

Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion

open access: yesCell Reports, 2013
Strategies for expanding hematopoietic stem cells (HSCs) include coculture with cells that recapitulate their natural microenvironment, such as bone marrow stromal stem/progenitor cells (BMSCs).
Joan Isern   +16 more
doaj   +1 more source

Coculture of LX2 Cells with HepG2.

open access: yes, 2016
Coculture of LX2 HSCs with high-OPN secreting HepG2 cells induced activation of HSCs while blockade of OPN via APT reverses these effects. Data are presented as mean ± standard deviation of the mean.
V. Chang (3390410)   +10 more
core   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

open access: yesAdvanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab   +8 more
wiley   +1 more source

Comparative Study on the Sand Bioconsolidation through Calcium Carbonate Precipitation by Sporosarcina pasteurii and Bacillus subtilis

open access: yesCrystals, 2018
To investigate potential implications of microbial activity on sand bioconsolidation and subsurface environments, two ureolytic strains, Sporosarcina pasteurii and Bacillus subtilis were tested for the production of calcium carbonate (CaCO3).
Chun-Mei Hsu   +8 more
doaj   +1 more source

Data_Sheet_1_Proteomic Analysis of a Syntrophic Coculture of Syntrophobacter fumaroxidans MPOBT and Geobacter sulfurreducens PCAT.xlsx

open access: yes, 2021
We established a syntrophic coculture of Syntrophobacter fumaroxidans MPOBT (SF) and Geobacter sulfurreducens PCAT (GS) growing on propionate and Fe(III). Neither of the bacteria was capable of growth on propionate and Fe(III) in pure culture. Propionate
Vicente T. Sedano-Nunez (11770319)   +5 more
core   +1 more source

Analysis of Tooth Innervation in Microfluidic Coculture Devices [PDF]

open access: yes, 2020
Innervation plays a key role in the development, homeostasis, and regeneration of organs and tissues. However, the mechanisms underlying these phenomena are not well understood yet.
Pagella, Pierfrancesco   +3 more
core   +1 more source

Tunable population dynamics in a synthetic filamentous coculture [PDF]

open access: yes, 2022
Microbial cocultures are used as a tool to stimulate natural product biosynthesis. However, studies often empirically combine different organisms without a deeper understanding of the population dynamics.
Ivan Schlembach   +13 more
core   +1 more source

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