Results 31 to 40 of about 5,297,063 (270)

Establishment of a coculture in vitro model for assessing biomaterials for bone regeneration

, 2023
embargoed_20261211Bone defects are mainly caused by inflammation, trauma and injury. The use of grafts is therefore necessary to replace damaged tissue.
BARBOLINI, GIORGIA
core  

An In Vitro Model for the Ocular Surface and Tear Film System

Scientific Reports, 2017
Dry eye is a complicated ocular surface disease whose exact pathogenesis is not yet fully understood. For the therapeutic evaluation and pathogenesis study of dry eye, we established an in vitro three-dimensional (3D) coculture model for the ocular ...
Qiaozhi Lu, Hongbo Yin, Michael P. Grant, Jennifer H. Elisseeff   +3 more
doaj   +1 more source

A Novel Human Stem Cell Coculture System That Maintains the Survival and Function of Culture Islet-Like Cell Clusters

, 2009
Islet-like cell clusters (ICCs) have been suggested to be a source of insulin-producing tissue for xenotransplantation in type 1 diabetes. We designed an approach to maintain the cultured rat pancreatic ICC survival and function, when cocultured with ...
趙國卿;趙國芳;陳呈峰;劉興華, CHAO, KUO CHING;CHAO, KUO-FANG;CHEN, CHENG-FENG;LIU, SHING-HWA   +1 more
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Comparing the value of mono- vs coculture for high-throughput compound screening in hematological malignancies [PDF]

, 2023
Large-scale compound screens are a powerful model system for understanding variability of treatment response and discovering druggable tumor vulnerabilities of hematological malignancies.
Dreger, Peter, Müller-Tidow, Carsten; https://orcid.org/, Herbst, Sophie A; https://orcid.org/, Kolb, Carolin, Zenz, Thorsten; https://orcid.org/, Roider, Tobias; https://orcid.org/, Huber, Wolfgang; https://orcid.org/, Bruch, Peter-Martin; https://orcid.org/, Kim, Vladislav; https://orcid.org/, Knoll, Mareike, Liebers, Nora, Lu, Junyan, Dietrich, Sascha; https://orcid.org/, Schitter, Eva C   +13 more
core   +1 more source

Co-culture models for investigating cellular crosstalk in the glioma microenvironment

Cancer Pathogenesis and Therapy
Glioma is the most prevalent primary malignant tumor in the central nervous system (CNS). It represents a diverse group of brain malignancies characterized by the presence of various cancer cell types as well as an array of noncancerous cells, which ...
Xiaodong Niu, Yan Zhang, Yuan Wang
doaj   +1 more source

Epicardial adipose tissue, metabolic disorders, and cardiovascular diseases: recent advances classified by research methodologies

MedComm, 2023
Epicardial adipose tissue (EAT) is located between the myocardium and visceral pericardium. The unique anatomy and physiology of the EAT determines its great potential in locally influencing adjacent tissues such as the myocardium and coronary arteries ...
Yujie Song, Yanzhen Tan, Meng Deng, Wenju Shan, Wenying Zheng, Bing Zhang, Jun Cui, Lele Feng, Lei Shi, Miao Zhang, Yingying Liu, Yang Sun, Wei Yi   +12 more
doaj   +1 more source

A Model Roseobacter, Ruegeria pomeroyi DSS-3, Employs a Diffusible Killing Mechanism To Eliminate Competitors

mSystems, 2020
The Roseobacter clade is a group of alphaproteobacteria that have diverse metabolic and regulatory capabilities. They are abundant in marine environments and have a substantial role in marine ecology and biogeochemistry.
Garrett C. Sharpe, Scott M. Gifford, Alecia N. Septer   +2 more
doaj   +1 more source

Microfluidic effects of transporting signaling components in cell coculture chips

, 2009
A theoretical model has been developed to investigate the microfluidic transport of the signaling chemicals in the cell coculture chips. Using an epidermal growth factor (EGF)-like growth factor as the sample chemical, the effects of velocities and ...
Hu GQ(胡国庆), Dongqing Li, Li DQ
core   +1 more source

Coculture development.

, 2020
10× magnification. (A) Control coculture of RL-14 cardiomyocytes and 3T3 fibroblasts. The red arrows point to cardiomyocytes and the light green arrows to fibroblasts.
Yuliet Montoya (8486523), Paola Orozco (8486520), John Bustamante (671834)   +2 more
core   +1 more source

Micromarrows-three-dimensional coculture of hematopoietic stem cells and mesenchymal stromal cells [PDF]

, 2012
Hematopoietic stem cell (HSC) transplant is a well established curative therapy for some hematological malignancies. However, achieving adequate supply of HSC from some donor tissues can limit both its application and ultimate efficacy.
Kerry Atkinson, Gary Brooke, Rice, Alison, Kathryn Futrega, Kabiri, Mahboubeh, Brooke, Gary, Cook, Matthew M., Osiecki, Michael, Futrega, Kathryn, Matthew M. Cook, Mahboubeh Kabiri, Atkinson, Kerry, Kul, Betul, Doran, Michael, Michael Osiecki, Michael Doran, Betul Kul, Alison Rice   +17 more
core   +1 more source