Results 11 to 20 of about 5,297,063 (270)

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo. [PDF]

Adv Sci (Weinh)
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Li M, Lyu J, Li K, Dravid A, Balasubramani D, K Ashkezari AH, Choi HK, Kwong GA, Singh A, Zhu C.   +9 more
europepmc   +2 more sources

Anti-Inflammatory and Cytotoxicity Effects of Cudrania tricuspidata Fruits Vinegar in a Co-Culture System with RAW264.7 Macrophages and 3T3-L1 Adipocytes

Foods, 2020
Vinegar has been found to have in vitro improvement effect on inflammatory biomarkers, and clinically used to improve inflammation and obesity-related diseases.
Jun-Hui Choi, Se-Eun Park, Soo-Hwan Yeo, Seung Kim   +3 more
doaj   +1 more source

Evaluation in a Cytokine Storm Model In Vivo of the Safety and Efficacy of Intravenous Administration of PRS CK STORM (Standardized Conditioned Medium Obtained by Coculture of Monocytes and Mesenchymal Stromal Cells)

Biomedicines, 2022
Our research group has been developing a series of biological drugs produced by coculture techniques with M2-polarized macrophages with different primary tissue cells and/or mesenchymal stromal cells (MSC), generally from fat, to produce anti ...
Juan Pedro Lapuente, Gonzalo Gómez, Joaquín Marco-Brualla, Pablo Fernández, Paula Desportes, Jara Sanz, Mario García-Gil, Fernando Bermejo, Juan Víctor San Martín, Alicia Algaba, Juan Carlos De Gregorio, Daniel Lapuente, Almudena De Gregorio, Belén Lapuente, Sergio Gómez, María de las Viñas Andrés, Alberto Anel   +16 more
doaj   +1 more source

Secreted Factors from Keloid Keratinocytes Modulate Collagen Deposition by Fibroblasts from Normal and Fibrotic Tissue: A Pilot Study

Biomedicines, 2020
Interactions between keratinocytes and fibroblasts in the skin layers are crucial in normal tissue development, wound healing, and scarring. This study has investigated the role of keloid keratinocytes in regulating collagen production by primary ...
Mansour A. Alghamdi, Laith N. AL-Eitan, Andrew Stevenson, Nutan Chaudhari, Nicole Hortin, Hilary J. Wallace, Patricia L. Danielsen, Mitali Manzur, Fiona M. Wood, Mark W. Fear   +9 more
doaj   +1 more source

A computer vision approach for analyzing label free leukocyte trafficking dynamics on a microvascular mimetic

Frontiers in Immunology, 2023
High-content imaging techniques in conjunction with in vitro microphysiological systems (MPS) allow for novel explorations of physiological phenomena with a high degree of translational relevance due to the usage of human cell lines.
S. Danial Ahmad, Mujdat Cetin, Mujdat Cetin, Richard E. Waugh, James L. McGrath   +4 more
doaj   +1 more source

Case studies in coculture syntrophy and 13C metabolic flux analysis

, 2022
Antoniewicz, Maciek R.Papoutsakis, Eleftherios T.Engineering microbial consortia for fermentation allows for pathway compartmentalization, broadened metabolic capability, and improved robustness.
Dahle, Michael Lynn
core   +1 more source

Multi-Costimulatory Pathways Drive the Antagonistic Pseudoalteromonas piscicida against the Dominant Pathogenic Vibrio harveyi in Mariculture: Insights from Proteomics and Metabolomics

Microbiology Spectrum, 2022
Vibrio harveyi is the dominant pathogen in mariculture, and biocontrol of this pathogen using antagonistic probiotics is a long-standing biological challenge.
Wei Ren, Bingqing Xue, Feifei Cao, Hao Long, Yanhua Zeng, Xiang Zhang, Xiaoni Cai, Aiyou Huang, Zhenyu Xie   +8 more
doaj   +1 more source

Prevascularization techniques for dental pulp regeneration: potential cell sources, intercellular communication and construction strategies

Frontiers in Bioengineering and Biotechnology, 2023
One of the difficulties of pulp regeneration is the rapid vascularization of transplanted engineered tissue, which is crucial for the initial survival of the graft and subsequent pulp regeneration.
Qiao Ruan, Shenglong Tan, Li Guo, Dandan Ma, Jun Wen   +4 more
doaj   +1 more source

Metabolic Synergy between Human Symbionts Bacteroides and Methanobrevibacter

Microbiology Spectrum, 2022
Trophic interactions between microbes are postulated to determine whether a host microbiome is healthy or causes predisposition to disease. Two abundant taxa, the Gram-negative heterotrophic bacterium Bacteroides thetaiotaomicron and the methanogenic ...
Jennie L. Catlett, Sean Carr, Mikaela Cashman, Megan D. Smith, Mary Walter, Zahmeeth Sakkaff, Christine Kelley, Massimiliano Pierobon, Myra B. Cohen, Nicole R. Buan   +9 more
doaj   +1 more source

Quantitative and Qualitative Image Analysis of In Vitro Co-Culture 3D Tumor Spheroid Model by Employing Image-Processing Techniques

Applied Sciences, 2021
This work proposes a novel region-estimation (RE) algorithm using the quantification of colon-cancer (HCT-8) and fibroblasts (NIH3T3) cells to estimate the densest region of colon-cancer cells in in vitro 3D co-cultured spheroids.
Mukta Sharma, Venkanagouda S. Goudar, Manohar Prasad Koduri, Fan Gang Tseng, Mahua Bhattacharya   +4 more
doaj   +1 more source