Results 1 to 10 of about 24,710 (133)
Coculture techniques for modeling retinal development and disease, and enabling regenerative medicine [PDF]
Stem Cells Translational Medicine, 2020 Abstract Stem cell-derived retinal organoids offer the opportunity to cure retinal degeneration of wide-ranging etiology either through the study of in vitro models or the generation of tissue for transplantation. However, despite much work in animals and several human pilot studies, satisfactory therapies have not been developed.
David Steel +2 more
exaly +6 more sources
Recent advances in multicellular human liver models [PDF]
Organoid, 2022 The liver is the most important metabolic organ in the body. Model systems that recapitulate the complex organ structure and cell composition of the human liver are insufficient to study liver biology and to test toxicity and efficacy during new drug ...
Seon Ju Mun +5 more
doaj +1 more source
Scientific Validation and Clinical Application of Lung Cancer Organoids
Cells, 2021 Lung cancer organoid (LCO) is a novel model of lung cancer that facilitates drug screening. However, the success rate of LCOs varies from 7% to 87%, and the culture medium compositions are markedly different.
Dahye Lee, Yoonjoo Kim, Chaeuk Chung
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A Review of Functional Analysis of Endothelial Cells in Flow Chambers
Journal of Functional Biomaterials, 2022 The vascular endothelial cells constitute the innermost layer. The cells are exposed to mechanical stress by the flow, causing them to express their functions.
Makoto Ohta +5 more
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Adaptation of a coculture technique to the Minitek anaerobe system [PDF]
Journal of Clinical Microbiology, 1985 A method to produce anaerobic conditions by coculture with a nonfermentative organism was utilized in conjunction with the Minitek anaerobe system (BBL Microbiology Systems, Cockeysville, Md.) for identification of anaerobic bacteria from clinical specimens.
Z, Hussain +3 more
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Endometrial cocultured cells in assisted reproduction techniques [PDF]
Journal of Clinical and Experimental Investigations, 2016 Objective: Endometrium, which plays a very important role in reproductive biology and one of the pathologies connected with it as are the problems in the implantation. One of the most important processes for the female fertility are experienced in implantation failure and one of the developed methods for the solution are endometrial coculture ...
Leyla Bahar, Semra Kahraman
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Protecting islet functional viability using mesenchymal stromal cells
Stem Cells Translational Medicine, 2021 Islet transplantation is an emerging treatment for type 1 diabetes which offers the prospect of physiological control of blood glucose and reductions in acute hypoglycaemic episodes.
Ella L. Hubber +2 more
doaj +1 more source
Micromachines, 2023 The complex synaptic connectivity architecture of neuronal networks underlies cognition and brain function. However, studying the spiking activity propagation and processing in heterogeneous networks in vivo poses significant challenges.
Yana Pigareva +7 more
doaj +1 more source
Screening of Health-Associated Oral Bacteria for Anticancer Properties in vitro
Frontiers in Cellular and Infection Microbiology, 2020 While extensive literature exists about the role of oral bacterial pathogens like Porphyromonas gingivalis and Fusobacterium nucleatum in oral squamous cell carcinoma (OSCC), the role of health-associated species has been largely unexplored.
Divyashri Baraniya +8 more
doaj +1 more source
Application of a single‐colony coculture technique to the isolation of hitherto unculturable gut bacteria [PDF]
Microbiology and Immunology, 2015 ABSTRACTMolecular studies have led to postulation of a relationship between gut microbiota and certain diseases. However, because studies of hitherto uncultured species in vivo are essential for characterizing the biology and pathogenic properties of gut bacteria, techniques for culturing and isolating such bacteria must be developed. Here, a technique
Yoshiki, Tanaka, Yoshimi, Benno
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