Results 131 to 140 of about 11,564,024 (351)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

PERAN ETIKA KEPRIBADIAN DAN KODE ETIK GURU DALAM MENINGKATKAN KUALITAS PEMBELAJARAN

open access: yesGuruku
The teacher code of ethics is an important guideline in carrying out professional duties as an educator. This article discusses in depth the principles of the teacher code of ethics, its role in education, and its implications for the quality of learning.
Silvia Neltiana, Rahmi Putri
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Minimizing bugs in cognitive neuroscience programming

open access: yesFrontiers in Psychology, 2014
Vadim eAxelrod, Vadim eAxelrod
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Embedding Explainable AI for Code Quality Prediction in Devops

open access: yes
openPredicting code errors can be very useful for software developers to prevent post-release defects. There are several mathematical models that make this prediction, such as logistic regression (from the linear regression family) and a black box model (
VINTI, LUCA
core  

Quality Assurance Agency Subject Benchmark Statement : Forensic Science

open access: yes, 2012
Subject benchmark statements provide a means for the academic community to describe the nature and characteristics of programmes in a specific subject or subject area.
Willison, Debra   +1 more
core  

Analysis of ChatGPT-Generated Codes Across Multiple Programming Languages

open access: yesIEEE Access
Our research focuses on the intersection of artificial intelligence (AI) and software development, particularly the role of AI models in automating code generation. With advancements in large language models like ChatGPT, developers can now generate code
Sally Almanasra, Khaled Suwais
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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