Results 91 to 100 of about 48,173 (292)

Efficacy and practicality of codeine [PDF]

Canadian Medical Association Journal, 2011
Thank you for bringing this important issue to the attention of CMAJ’s readership.1 As clinicians, we all wish to deliver evidence-based and effective pain treatment to our patients by considering efficacy, safety and practicality. The editorial focused on safety; we’d like to highlight the limitations of codeine in the other areas.
Amy L. Drendel, Samina Ali
openaire   +3 more sources

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

Drug Testing and Analysis, EarlyView.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer, Maximilian Ninnig, Lea Wagmann, Sascha K. Manier, Markus R. Meyer   +4 more
wiley   +1 more source

Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety [PDF]

, 2010
<p>Background: Melatonin is extensively used in the USA in a non-regulated manner for sleep disorders. Prolonged release melatonin (PRM) is licensed in Europe and other countries for the short term treatment of primary insomnia in patients aged 55 ...
A Brzezinski, A Chesson, AG Wade, AJ Lewy, Alan G Wade, Alex McConnachie, C Cajochen, C Liu, CA Czeisler, D Buysse, D Garfinkel, D Leger, DJ Buysse, DJ Kennaway, E Grossman, EM Gibson, G Hajak, G Mayer, Gordon Crawford, H Nakagawa, HJ Lynch, I Haimov, I Haimov, Ian Ford, IV Zhdanova, J Backhaus, JG MacFarlane, JK Wyatt, M Littner, M Littner, M Sharma, MA Hofman, MA Paul, Moshe Laudon, N Buscemi, N Zisapel, Nava Zisapel, OL Bech P, P Lemoine, P Tyrer, R Luthringer, R Mahlberg, R Mahlberg, S Ancoli-Israel, SW Lockley, T Gorfine, T Gorfine, T Roth, T Shochat, Tali Nir, W Guy, World Psychiatric Association, YH Wu   +52 more
core   +3 more sources

Workplace Drug Testing—Prevalence of Positive Test Results, Most Common Substances, and Importance of Medical Review

Drug Testing and Analysis, EarlyView.
Among 23,900 urine and oral fluid drug tests from Swedish workplaces, 4.6% tested positive for controlled substances. Cannabis, amphetamine, cocaine and benzodiazepines were most common. Many samples containing opiates, amphetamine or benzodiazepines were MRO verified as being due to medical prescriptions, while cannabis or cocaine were almost entirely
Anders Helander, Fredrik Sparring
wiley   +1 more source

Exploring Australian pharmacists’ perceptions and attitudes toward codeine up-scheduling from over-the-counter to prescription only

Pharmacy Practice, 2020
Objective: Explore the perceptions, attitudes and experiences of pharmacists relating to the up-scheduling of low dose codeine containing analgesics and the impact on pharmacy practice.
Melanie McKenzie , Jacinta Johnson , Karen Anderson , Richard Summers , Pene Wood   +4 more
doaj   +1 more source

Anti‐Doping Testing at FIFA World Cup 2022

Drug Testing and Analysis, EarlyView.
The FIFA 2022 World Cup was fully accomplished by the Anti‐Doping Lab Qatar. The article describes the doping analysis work, achievements, and lab structure in details. ABSTRACT The 22nd FIFA World Cup, the world championship for national football teams, was held in Qatar from November 20th to December 18th, 2022.
Alanod D. AlQahtani, Wadha Abushareeda, Ariadni Vonaparti, Suhail Kraiem, Wesal ElSaftawy, Khadija Saad, Aisha Al‐Wahaibi, Nayla Hilal, Najib Dbes, Vandana Nimker, Alexis Weber, Alka Beotra, Mohammed Al Maadheed   +12 more
wiley   +1 more source

Optimization of Parallel Artificial Liquid Membrane Extraction for the Determination of Over 50 Psychoactive Substances in Oral Fluid Through UHPLC–MS/MS

Drug Testing and Analysis, EarlyView.
This study is related to the development of a microextraction method for the determination of 56 psychoactive substances in oral fluid. Sample clean‐up is obtained by parallel artificial liquid membrane extraction and analyzed by liquid chromatography–tandem mass spectrometry.
Martina Croce, Camilla Montesano, Ilenia Bracaglia, Francesco Bartolini, Marcello Mascini, Dario Compagnone, Manuel Sergi   +6 more
wiley   +1 more source

Over-The-Counter Codeine: Can Community Pharmacy Staff Nudge Customers into Its Safe and Appropriate Use?

Pharmacy, 2020
The misuse of opioids, including codeine which is sold over-the-counter (OTC) in United Kingdom (UK) community pharmacies, is a growing public health concern. An educational Patient Safety Card was developed and piloted to see if it nudged customers into
Sapana Mody, Charlotte L. Kirkdale, Tracey Thornley, Aimi Dickinson, Anthony J. Avery, Roger Knaggs, Sarah Rann, Ruth Bastable   +7 more
doaj   +1 more source

Infant Death due to Cannabis Ingestion

Drug Testing and Analysis, EarlyView.
ABSTRACT A child died in the emergency room of a local hospital a few hours after ingesting a substance the color of cork and the consistency of earth. At home, a modest amount of resinous substance was found. At the hospital, the child exhibited alterations in walking, balance, and consciousness.
Donata Favretto, Antonello Cirnelli, Roberto Pertile, Raffaella Stimamiglio, Clara Cestonaro, Oriana Cuman, Anna Pagliaro, Fabio Mattiazzi, Cristina Basso, Maddalena Galeazzi   +9 more
wiley   +1 more source

CYP2D6 drug-gene and drug-drug-gene interactions among patients prescribed pharmacogenetically actionable opioids [PDF]

, 2017
Purpose When codeine and tramadol are used for pain management, it is imperative that nurses are able to assess for potential drug-gene and drug-drug-gene interactions that could adversely impact drug metabolism and ultimately pain relief.
Broome, Marion E., Burke Draucker, Claire, Carpenter, Janet S., Holmes, Ann M., Knisely, Mitchell R., Skaar, Todd C., Von Ah, Diane   +6 more
core   +1 more source