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Anaesthesia, EarlyView.Summary Introduction Most patients undergoing elective surgery in the UK are discharged from hospital on the same day. Despite this, there is a lack of UK patient‐centred outcome measures relating to quality of recovery, pain and analgesic use. The POPPY study was a UK‐wide prospective, observational study measuring short‐ and longer‐term patient ...
Martha Belete, Adam B. Brayne, Harriet Daykin, Matthew Everson, William M. Hare, Anna Ratcliffe, Lexy Sorrell, the POPPY study delivery group, Mark Rockett, on behalf of the Research and Audit Federation of Anaesthetists in Training, Katie Samuel, Xiaosu Jiang, Hayaka Amada, Lisa Ditchfield, Nkiruka Obiakpolam, Rebekah Chan, Lauren Mahoney, Rebecca Madew, Kristian Tattam, Shannon Collings, Harry Bamber, Lee Baines, Michael Thurm, Gearoid Crosbie, Felicity Hamilton, K. Hempenstall, Rabiat Umar, Alicia Ibbotson, Jolyon Flint Cahan, Tushar Das, Stuart Evans, Davina Hewitt, Sian Mckee, Joe Mellor, Mathew Patteril, Dawn Davies, Shiji Thomas, Jesty Thomas, Charlie Bevan, Natalie Kenny, Fenella Podd, Sindhu Sapru, Shilani Sundaram, Richie Field, Ellie Whittingham, Ben Wilkinson, Geetanjali Verma, Jayne Sewell, Grace Killingsworth, Sapna Chakranarayan, Beverley Wilkinson, Patricia Nicholls, Irfan Ulhaq, Mudola Manyano, Myo Thet Paing Lin, Katherine Davidson, Jane Gregory, Zoe Saunders, Rhona Bill, Antoinette Wilson, Diane Armstrong, Aku Iboroma, Abhinav Kant, Holly Davies, Manabendra Haldar, Ben Thompson, Myra Khan, Thomas Ballance, Sarah Cook, Matthew Stokle, Abby minette, Tori Hanson, Marilyn Cooper, Natasha Mulley, Jerry Thomas, Georgina Chapman, Luke Patterson, Renjith joseph, Praveen Gunasekaran, Dorota Potoczna, Lindsey Bennett, Kathy Dent, Kirsty Nauyokas, Sandra Pearson, Sue Spencer, Bahaael Din El Sady, Jenetha Rajendram, Annie Wood, Keiran Dudden, Caroline Kane, Sophia Hamilton, Dipayan Choudhuri, Peter Sykes, Florence Emond, Florian Fischer, Ian Edmond, Ryad Chebbout, Iona Lennie, John Ochiltree, Maria Blaney, Thalia Massa, Srinivas Magham, Ankit Kedia, Vaisakh Viswanathan, Saqib Khan, Malathi Jabanathan, Eleni GRANI, Eleni Grani, Rosemary Harper, Anna Pierson, Nomonde Laxa, Allan Clark, Chinenyenwa Amaraihe, Christopher Dixon, Haneefa Ali, Purnima Narasimhan, Jessica Biggs, Keslin Greenwood, Bhavesh Gohil, James Lamert, Michael Sawaryn, Alice Gao, Lynden Nicely, Ruth Parker, Ismail El‐Kharbotly, Zheyna Konstantinova, Bilal Afzal, Abu Kalam, Holly Mcquarrie, Shuaib Sheikh, Muhammad Furqan, Praveena Chand, Sofia Theodoridou, Fotios Gkioulos, Laura Fulton, Benjamin Cooper‐Drake, Asya Veloso Costa, Edward Gill, Bhavesh Gohil, Laura Edwards, Henry Somers, George Budden, Bhavesh Gohil, Deirdre Guerin, Kim Jemmett, John Cockcroft, Ahmed Hassan, Arisa Reka, Eleanor Plews, Jack Whiting, Richard Buckley, Reanne Solly, James Rand, Sarah Stirrup, Emma Ingall, Olajumoke Owolabi, Sabeen Tufail, Sindu Sridhar, Victoria Fisher, Kimberley Netherton, Amy Faunt, Jane Upsall, Daniel Stolady, Karan Verma, Sian Liddle, David Chapman, Stefan Kourdov, Daniel Jafferji, Jayakadumudiyanselage Jayakadu, Nikhil Singh, Udara Wickramanayake, Zi Soo, Hannah Neil, Johannes Retief, Kelly Barrett, Catherine Marshall, Alice Cato, James Norton, Kirsty Pearce, Oliver Main, Isabelle Mayne, Sophy Booth, Daisy Flanagan, Laura Helley, Jordan Hargreaves, Bethan Morgan, Victoria Maples, Nour Shubber, Claire Stringer, Noori Suhail, Samuel Small, Charlotte Beresford, Hoi Ching Fung, Rebecca Parker, Amy Szuman, Heather MacFarlane, Loveleena Gupta, Bunyad Naqvi, Harry Holkham, Islam Ahmed, Daniel Slane, Basant Bhattari, Vincent Chan, Abby Collins, Dean Wilkinson, Jessica Jones, Joanna Renée, Ross Gillespie, Éireann Allen, Jakub Foytl, Alexandra Vine, Lucy Dobbs, Matthew Dunne, Anna Boyer, Judith Highgate, Marten Lau, Tanmay Jain, Mennatuallah Khedr, Mohamed Abdo, Ahmed Aboelezz, Sarah Goodwin, Adam Pickard, James Cartwright‐Gill, Matthew Cadd, Rory Mercer, Judith Highgate, Marten Lau, James Andren, Tanmay Jain, Sampson Anya, Alice Hipsey, Tom Searle, Amr Elmosalamy, Mennatu‐Allah Khedr, Tanya Hossain, Danielle Simpson, Juliette Kemp, Vanessa Badas, Matthew Lettis, Charlotte Jewell, Thomas Doel, Charles Kennedy, Caroline Wrey Brown, Emily Bevan, Maria Alvarez Corral, Joanna Moon, Kerry Taylor, Joanna Simpson, Clare Bird, Femi Adetunji, Nipun Mundkur, Lynsey Crowley, Emma Williams, Edyta Klata, Kerry Smith, Alison Ghosh, Katrina Cooke, Aashima Bakshi, Hannah Stansfield, Chiara Delenadis, Andrew Veal, Michael McGovern, Helena Dunn, Stella Gillies, Sarah El‐Sheikha, Clare Buffery, Emily Robinson, Anya Sheltawy, Ian Turner‐Bone, Laura Wilding, Harriet Murrant, Michaela Lloyd, Andrew Martin, Chris Jones, Elizabeth Whatling, Rachael Reddall, Kathrine Redington, Poppy Jenkinson, Fouad El‐Hibri, Berenice Cunningham‐Walker, Rachel Kearns, Iain Mactier, Munsoor Latif, Rowan Swan, Mina Zikry, Nicholas Yeo, Sarah Meredith, Emily Black, Kirsty McCrorie, Tom Baddeley, Clarissa Hocking, Faith Dalgatty, Simon Chitnis, Garry Davenport, Lisa Grimes, Georgina Singleton, Parameswari Chockalingam, Zarah Brown, Sabari Karthick Kumar, Lucy Miller, Benjamin Holdstock‐Brown, Oliver Totham, Nitya George, Priti Morzaria, Sachintha Hewage, Joseph Pease, Oliver Francis, Caroline Phillips, Vladimir Bashliyski, Rajan Mehta, Gabrielle Mendez, Alun Thomas, Elizabeth Henderson, Becky Icke, Charlotte Jones, Bethan Morse Browning, Bethan Landeg, Kevin Scott, Fiona Morris, Thomas Rae, Konara Mudiyanselage Ishan Madhuwantha Dharmarathna, Yuvaraj Doraiswamy, Lewis Isaac, Trudy Smith, Tracey Lewis, Linda O'Brien, Emma Perkins, Sunita Agarwal, Farah Nizar, Ibrahim Mostafa, Michelle Edwards, Erin Williams, Randeep Dhaliwal, Pawan Kootelu Pernu, Jane Doherty, Stephy Jose, William Flesher, Catriona Laverty, Abirami Kanniappan, Ikechukwu Igwebuike, Ramy Howaidi, Thomas Pinnock, Gabriel Ngui, E.M. Damith, E. Ekanayake, Matthew Hines, Elizabeth Stones, Karen Winter, Christopher Newell, Carys Lim, Francesca Millinchamp, Abigail Lau, Dominic Knight, Barbel Straube, David Quinn, William Gatfield, Thomas Snell, Rebecca Woolf, Jessica Casey, Hannah Hall, Katherine Lloyd Jones, Tessa Dessain, Rita Fernandez Garcia, Bashir Hamza, Nick Spittle, Nathan Griffiths, Bethel Agomoh, Abdul Alim Khan, Charlotte Morris, Benedict Jong, Andrew Orsi, Manvir Sandher, Jessica Trinquet, John Slattery, Lesley Stevenson, Rheanna Smith, Emma Moakes, Elaine Willoughby, Sarah Broadhead, Caroline Thomas, Ahmed Ibrahim, Matthew Gowshall, Maheeka Nirmalee Rajamuni, Kanmani Tumkur Lakshmikantha, John Paul, Tetiana Khinalska, Amy Longhurst, Sarah Perrin, Jack Sherlock, Kieran Bradley, Niranjala Wickramasinghe, Rosie McMahon, Charlotte Adcock, Cindy Nguik, Liaw Qian Yan, Brendan Sloan, Chloe Start, Sarah Buckley, Amy Major, Megan Pursglove, Fatima Begum, Harriet Elson, Martin Sylvester, Sagar Sanadi, Lawrence Hamshaw, Benjamin Whitby, Sarah Watson, Ahmed Daoud, Lucy Scott, James Roden, Daliya Mathew, Louise Parker, Thelma Darian, Jessica Wilson, Geraint Rees, Anna Gilfedder, Alexandra Jenkins, Katherine Davies, Thomas Clarke, Adam Mounce, Megan Williams, Niall Doherty, Santhana Kannan, Rebecca Grenfell, Saba Kouser, Balu Balakrishnan, Kiran Rohalu, Amy Orme, Angela Sawyers, Nikhil Sarma, Mohyman El Habishi, Hussein Said, Satya Anantapatnaikuni, Sean Cope, Jeevan Subramaniam, Bilal Mohammed, Catherine Chikerema, Rachel Dimery, Daniel Campbell, Jamie McPherson, Rosanne Cope, Antonia Snell, Haris Arslan, Ciaran Murphy, Janaki Pearson, Torbert Chan, Thomas Walker, Hannah Clancy, Fred Hett, Sarah Wheelwright, Tony Hodgetts, Jeffrey Tsang, Jhanielle Quindoyos, Joanna Deery, Eva Beranova, Tracy Hazelton, Aarushi Agrawal, Charlene Barter, Beata Biro, Biplob Borthakur, Chinthaka Hewavitharane, Prathiban Kumar, Michael Papadopoulos, Edward Parkinson, Rebecca Phillips, Camilla Pople, Rose‐Anne Nunoo, Dushyant Sharma, Peratheepa Vimalatharmaiyah, Dinusha Wijerathna, Tamer Younes, Anna Walton, Alexander Hollis, Frances Wensley, Suzanne Shuttleworth, Christopher Tyllyer‐Veal, David Haydock, Eleanor Jones, Nicola Bax, Oscar Hardy, Shiv Vohra, Simon Cais, Vaarisan Ganeshalingam, Karen Salmon, Benjamin Griffiths, Belinda Roberts, Jonathon Biss, Pallavi Samir Marghade, Meera Tharmaratnam, Alpen Shah, Fabiha Parveen, Alfred Ball, Amarnath Moni, Dawn Cairns, Sarah Barton, Sophie Harris, Jane Thomas, Emily Redman, Michelle Eve, Faye Benson, Kerry Goodsell, Bushena Miyesa, Michael Villaruel, Aimee Williams, Sofia Matias, Tolu Oyinlade, Nai Ramirez, Stacey Pepper, Guy Rousseau, Elena Williams, Cathy White, Ashley Hanson, Fenella Johnson, Katy Pyatt, Roshni Dholakia, Nikita Missula, Naomi Adey, Alex Edmonds, James Reilly, Mansoor Sange, Salman Ahmad, Sheena Cheung, Apurva Patil, Jennifer Phillips, Laura Kemp, Enoch Onya, Mano Sengottian, Rabia Tariq, Rajendra Pun, Ahmed Ahmed, Asad Masood, Kanika Arora, Ruairidh Morgan, Sara Yousaf, Shangeeth Shangar, Nilarne Jeyashiri, Eleni Grani, Rosemary Harper, Una Poultney, Rachel Mutch, Wendy Armstrong, Eleni Grani, Laura Perry, Martina Caranza, Nils Kaufmann, Tom Georgi, Vanessa Rivers, Bally Purewal, Anneka Burch, Cathleen Chabo, Alison Swift, Rebecca Game, Rebecca Francis, Caitlin Palmer, Genessa Peters, Teresa Theobold, Daniel Watkins, Venkat Prasad, Pearl Baker, Hazel Amarado, Anna Fajardo, May Reyes, Anita Holme, Gloria Sikapite, Eunice Doctolero, Martin Ebon, Sheena Lim, Ashling Jonsson, Joy Derigay, Anna Price, Carina Cruz, Umesh Mistry, Abigail Gallagher, Kirthika Mohanathass, Matthew Woods, Laura Dan, Muriel Sirgi, Alexander Butcher, Tim Cook, Matthew Peacock, Isabel Lever, Thea Morgan, Matthew Hillier, Nicola Crowther, Sarah Hierons, Helen Burton, Tonia Clark, Gabrielle Evans, Carrie Demetriou, Maxine Brown, Joyce Katebe, Mayank Kumar Kulshrestha, Lara Allen, Ceren Senver, Katherine Meadows, Thomas Taylor, Sapphire RouXi Tan, Hebah Babar Iqbal Afridi, Junais Abdul Jaleel, Saarah Rana, Reham Deraz, Dominika Raciborska, Benjamin Straughan, Guy Hardwick, Shona Smith, Muhammad Imran Riasat, Manu Sudevan, Alasdair Turnbull, Andrew Baigey, Daniel Lynch, Joy Dawson, Nicola Butlin, Allison Roebuck, Sarah Davison, Melanie Tolson, Nicholas Ireland, Lindsay Dawson, Emma Allen, Nicola Hirschauer, Laura McAughtrie, Graham Harris, Claudia Wilson, Jack Kavalier, Euan Allan, Adam Crellinh, David Saunders, Nicola Atkinson, Mona Lehra, Adam Mowatt, Sarah Baxter, Matthew Pagan, Annie Newby, Caitlin Carr‐Knox, Aliasgar Shikiri, Rhona Sinclair, Yuvraj Kukreja, Sarah Mansoor, Rafeek Aziz, Ahmed Elfaioumy, Adela Dobru, David Berry, Mavis Cheng, Christopher Molloy, Oladele Olajolumo, Hayun Lee, Tasneem Ladha, Kandasamy Bharathi, Laura Perry, Daniel Watkins, Joellene Mitchell, Pritam Mohanty, Mhairi Davidson, Lisa Kean, Fiona Elliott, Melanie Bloor, Choopong Luansritisakul, Sarah Cockburn, Naomi Dugard, Jayne Edwards, Theresa Garratt, Barbara Linklater‐Jones, Asha Mohan, Meryl Owen, Sara Owen, Chloe Perry, Rebecca Davies, Richard Shawcross, Julie Steen, Ellen Thompson, Claire Wright, Terri Anderson, Sarah Clamp, Dan Redfern, Niall O'Reilly, Gemma Balfour, Krithi Ravi, Paul Murney, Catherine Humphreys, William Allingham, Ailidh Ramsay, Rajeev Jha, Min Xian Lim, Chantal Roberts, John Reidy, Philip Gardiner, Alisha Chauhan, Nosaiba Ezzelarab, Olaoluwa Olaosebikan, Raj McNab, Sarah Ranson, Rebecca Pugh, Caroline Rider‐Dobson, Gul Khan, Fleur Kirkpatrick‐Croll, Vikki Cooke, Georgia Hooton, Fiona Dunning, Angela Waddingham, Deborah Walstow, Gemma Rook, Sarah Farmer, Anna Hoogkamer, Joseph Gaynor, Joseph Greatorex, Owais Shah, Shivam Patel, Anil Hormis, Jennifer Southern, Caroline Bird, Cheryl Graham, Riya Rose Mathew, Jake Warrington, Tirth Vasa, Daniel Brimfield, Claire Williams, Phillip Smith, Abby Todd, Thomas Burr, Andrew Middleton, Sophie Prestidge, Subhani Abhayawardena, Amber Hurry, Rebecca Hawes, Rachel Walker, Kath Stenlake, Elliot Haines, Jess Henry, Jess Sinclair, Beth Shartau, Isobel Browne, Sara Salim, Lucy Barnes, Anisha Patrao, Jess McLaughlin, Siyan Patel, Bassam Ali, Bibiana Bien, Oliver Tomkins, Rukia Begum, Andy Savva, Peggy Fooks, Sachin Valap, Salma Abdul Majeed, Priyanka Boylla, Sidiq Aboobaker, Emmanuel Adeleye, Thomas Ainge, Uyi Asemota, Ashni Badiani, Anuradha Balagodage, Edward Borchardt, Palangutde Dimowo, Samahir Hussein, Achese Inimgba, Rebecca Partridge, Hathurusinghage Piyaratne, Shajira Rajanayagam, Prajwal Shetty, Kay Faulkner, Temitope Filade, Swarga George, Adam Henley, Parizade Raymode, Anish Thomas, Chole Stolarski, Linda Grant, Bev Liveley, Sally white, Ajay verma, Sharon Hilton‐Christie, Simon Watts, Simon Parkin, Natalia Albuquerque, Eilidh Gillen, Sharon Hilton‐Christie, Simon Watts, Simon Parkin, Natalia Albuquerque, Eilidh Gillen, Stephen Waite, Amy McGinlay, Sadasivan Chinniah, Owen Davies, Surbhi Abrol, Harry Farnham, Huiching Ho, Shaan Hyder, Justin Yim, Megan Brett, Kavitej Samra, Julie Naylor, Lauren Edie, Piriyanga Kesavan, Mukur Ghosh, Alberto Vitores, Michelle Bone, Emmah Nelly, Zainab Mavani, Raquel Calcada, Suzanne Woodhouse, Roxana Ciocan, Daniele Arcoria, Terri‐Anne Baker, Natalie Temple, Kirsty Allen, Elisa Barter, Ionela Sinanovic, Kerrie Cavanagh, Graeme McLintock, Venkat Sundaram, George Woods, Amanda Jones, Rachael Farnell, Victoria Saul, Angela Pye, Annette Bolger, Bethan Roberts, Delyth Rees, Jennifer Davies, Joanne Lewis, Victoria Garvey, Caroline Lees, Sahishnu Siva Ram, Joe Woodcock, Remil Ignatius, Lorraine Spencer, Manish Adke, Paul Kim, Laura Bridge, Roz Chisholm, Christopher Balestrini, Matthew Cox, Claudia Porteous, Matthew Priest, Sara James, Karl Hunter, Anne Reddington, Jack Maher, Melanie Maxwell, Caroline Reavley, Deirdre Fottrell‐Gould, Jane Platt, Daniel Sciberras, Eleanor Jarvis, Bridie Willan, Ann Toms, Emma Vallis‐Booth, Kate Tabrett, Ciaran Scott, Farooq Afzaal, Sehajdev Bhatia, Peter Lockett, Theresa Murray, Thomas Payne, Ben Cracknell, Rishabh Sethi, Akanksha Rathod, Aleix Ugalde, Kira Farrell, Zainab Najim, Rhiannon Jones, Niamh Ward, Tineesh Mathew, Anwuli Odili, Engy Samuel, Anne Kathrine Brinck Nielsen, Marian Wassef, Dominic Linden, Lucy Connolly, Timothy Poulton, Anais Mutarambirwa, Bethany Plummer, Mavi Venditti, Ishan Lalindra Wijesinghe, Linda Ofori, Patience Nkala, Dilukshi Wickramasinghe, Louise Brassington, Suzanne Williams, Robert Musalagani, Gayzel Vallejera, Cynthia Kenala, Sabita Pokharel, Lisa Parker, Tom Hatton, Trudi Chronnell, Jennifer May, Amelia van Manen, Sarah Hudson, Hanin Ramadan, Adam Taylforth, Aaron Fleming, Amy Tucker, Kate Rahnejat, Aimee Manicom, Adel Amer, Akshay Shah, Daniel Kent, Sophie Dunin, Yashasvi Perera, Nissy Georgealias, Eoin Kelleher, John Cruise, Henry Jefferson, George Gladstone, James Davies, Chris Morrell, James Goetz, Nikki Fry, Claire Preedy, Lucas De Carvalho, Eve Fletcher, Suzy Dean, Qian Zhang, Maisie Harvey, Elyanna Choi, Benjamin Tanner, Stephanie Edmunds, Sachin De Stone, Bethan Gay, Jack Walker, Kai Li, Ruth Child, Muhammad Zarif Miszua Anuar, Jemima Henstridge‐Blows, Edward Cope, William Ellis, Yoshimi Ito, Merin Joselin George, Sumreen James, Juliya Pearl Joseph Johnson, Deepshika Mehra, Dominic Wilson, Pranav Osuri, Sumant Shanbhag, Monisha John, Jack Houghton, Jason Patel, Ramdas Howard, Nyree Jackson, Blessing Okoko, Tegan Taylor, Kyle Chang, William Rea, Annu Abraham, Neelesh Kumar Mohan, Emma Prendergast, Craig Pinner, Kimberley Benjamin, Eleanor Keeling, Marcus Beadle, Jonathan Robinson, Bijay Mallikarjuna, Georgina Highton, Matt Rendell, Temi Ijiwole, Monica Horvath, Chandran Jeganathan, Sejung Park, Matthew Titterington, Victoria Estlin, Scarlett Wood‐Gismera, Amarjeet D Patil, Pei Shan Lim, Simon Hatton, Karl Braid, Mohammed Attia, Kailash Bhatia, Teodora Orasanu, Khaled Ahmed, Kelly Hubbard, Katie Dorr, Catherine Wyatt, Sarah Shephardson, Dinesh Rao, Anand Shirgaonkar, Farheen Samad, Harsimran Kaur Surinder Singh, Paul Parker, Samuel Saad, Teodora Orasanu, Lynn Osborne, Amy Faunt, Rayya Alharthi, Jane Upsall, Kimberley Netherton, Kelly Hubbard, Katie Dorr, Bret Claxton, Ciaran Clarke, Simon Cousins, Chuyan Yu, Ravi Mani, Elizabeth Smithson, Vei Tay, Kate Dalgleish, David Cronin, Kelly Sugden, Andrew Parrish, Rick Leggatt, Ian Chadderton, Beth Pullen, Helen Stanworth, John Dereix, Tony Hodgetts, Gabriella Tutt, Eliza Davies, Trudy Parfrey, Sharon Turney, Joanne Knight, Stephanie Berry, Timothy Bonham, Sarah Taylor, Wendy Stoker, Amy Foster, Jennifer Hooper, Thomas Padwick, Josephine Gwinnell, Calum Smith, Daniel Lenton, Sam Stafford, Chetan Pataki, Christopher Sadler, Rebecca SJ Gibson, Ellen Gorman, Monica Chogle, Ruth Ford, Matthew Gillen, Abdul Raziq Hider, Max Zammit‐Maempel, Jenny Eastwood, Aoife Deeny, Timothy Durkan, Renata Klopotowska‐Arszulowicz, Victoria Prabhu, Marino Lagadi, Renata Klopotowska‐Arszulowicz, Ahmed Makky, Roland Amoah, Anna Williams, Fiona Glarvey, Tom Abberton, Richard Scowcroft, Will Simpson, Iwan Williams, Judith Oguguo, Jodie Fletcher, Marco Azize, Stephen Davies, Daniel Young, Carol Jeffs, Vas Vasudevan, Mel Caswell, Stephen Preston, Lisa Elawamy, Leonie Benham, Favour Adoghe, Amy Barnett, Ailsa Uttley, Chris Hale, Haritha Harrision, Kayleigh Mountford, Ashleigh Wignall, Ron Manuel, Dona Solichan, Ancy John, XVL Holmwood, Henry Sergeant, Bertie Garbutt, Sophia Strong‐Sheldrake, Jessica Evans, Jo Chown, Drew Goodchild, Stephanie Walsh, Beena Eapen, Ginny Griffiths, Helen Burton, William Carroll, Emma Ewins, Nicholas Brown, Jessica Warr, Annabel Plumb, Carolyn Mansfield, Karen Gilbert, Esther Odesanya, Karen Hillyer, Georgina Rogers, Loku Warnapura, Orla Gillman, Ishita Bobba, James Gallagher Chin, Marwan Nassar, Michael Maseha, Nimali Puwackwaththa, Poojani Arulrajah, Runil Shah, Sabrina Saaid, Iain Cummings, Christopher McKee, Timothy Langdon, Victoria Allinson, Emily Johnson, Lydia Shatananda, Amman Mader, Zuzana Hutkova, Simon Grant, Pritesh Mistry, Antonia Stone, Shailendra Krishniah, Gopi Macherla, Neethu Raj, Nicholas Scallan, Holly James, Harminder Matharu, Emily Dana, Benjamin Robert Stevens, Sam Bullard, Charles Templeman, Sofia Farina, Keri Joslyn, Hans van Huellen, Charlotte Quick, Yolanda Baird, Benjamin Fenner, Anthony Short, Joshua Cooper, Jordan Coyle, Gemma McManus, Karen Aspey, Sazini Mtunzi, Cheryl Finch, Jane Olverson, Tobechukwu Eneh, Jayne Windebank, Saskia Port, Valerie Parkinson, Jennifer Anderson, David Wilcock, Susan Pemberton, Rebecca Smith, Tracey Taylor, Caroline Tierney, Ryan O'Leary, Lee Woolsey, Caroline Daniel, Emma Collins, Nagendra Prasad, Zaid Saghir Ahmed, Michael Nesbitt, Hannah Henderson, Zhen Xin Ong, Sherin Abdelbadiee, Emily Ruschen, Mechael Rafique, Luke Barge, Niamh Hetherington, Safa Asghar, Isabel Clark, Faiq Khan, Kevin Perera Padukkage, Daanyal Ilyas, Henriette Leser, Rifah Islam, Jaskiran Sandhu, Alys Williams, Jasmin Peacock, Alexander Van Loggerenberg, Alice Foulkes, Paige Wilkins, Beth Hancox, Maryam Umar, Sofia Korre, Namrata Kalra, Neha Isaac, Raaid Humdani, Grainne Moon, John O'Donoghue, Clodagh Krasucki O’Dowd, Jordan Lau, Emma Lee, John Conor Gildea, Aaron Duff, Aimee Thompson, Aidan McKinley, Sumayer Sanghera, Ahmed Atewah, Louise Murray, David Shaw, Gabrielle Harrison, James Morrison, Athira Sasidharan, William Stagg, Rebecca Morris, Vaishnavi Banagi Devaraju, Sara Piva, Luke Boyes‐Varley, Emily Gargan, Deepak Chhabra, Charlie Billington, Tom Casey, Robert Wiltshire, Chiu Kuan Joseph Lee, Claire Osey, Lindsay Rogers, Cheryl Lindsay, Chloe Bascombe, Fardowsa Ahmed‐Timms, Natalie Agius, Annamaria Wilce, Javen Ramsami, Charlotte Coekin, Charlotte Humphrey, Katie Preston, Suzanne Roffe, Karen O'Toole, Stephanie Worrall, Ramy Khalil, Emma Langridge, Yasmin DeAth, Matthew Bayliss, Anthony Pickering, Amy Ashford, Caroline Horrobin, Emily Bevan, Heather Hudson, James Richardson, Karen Bobruk, Kate Bell, Katherine Pass, Katie Foy, Katherine Saunders, Lewis Powell, Lydia Jones, Mary Trevelyan, Molly Monk, Rosina Jarvis, Rowena Johnson, Toni Farmery, William Hillier, Sumayer Sanghera, Amit Dalvi, James Sylvester, Jack Khalil, Matt Wiles, Abdelrahman Eleshmawi, Jaden Groves, Divyadarshni Vadivel, James Morrison, Reena Pal, Louis Rose, Jun Jie Lim, Alexandra Little, Michelle Agboola, Mark Plews, Tom Kingston, Natalie Lake, Hannah Dudhill, Freya Brownlow, Colaco Rohan John Francis Ronald Harris, Mhd Alaa Aldin Al Haffar, Rachel Lee, Branson Ng, Yvan Liew Jing Ying, Belal Yasin, Alistair Sawyerr, Mabli Davies, Joseph Hamlyn, Shilpee Kumari, John Finnerty, Helen Carr, Emma Lowe, Amrith Malhi, Lindsay Dawson, Patrick Eagle, Jane Stratton, Catherine Cromey, Brigitte Baxter, Mohammed Abdelmonem, Nicholas Palfrey, Joshua Feddon, Swyn Lewis, Lara Sabry, Adam Wood, Matt Irvine, Amanda Ebejer, Roopali Telang, James Ellis, Ahmed Abdella, Catherine Archer, Bharani Premkumar, Jenny Travers, Amanda Cook, Caradog Thomas, Marie Jones, Gemma Smith, Mark Baker, Claire Chapman, Sharon Storton, Marta Blanco Cabana, Nabil Farooqi, Priyankara Indrajith Marasinghe, Vinita Sangai, Munazzah Zaidy, Sylvia Martin, Shiba Aggarwal, Chloe Hall, Hemesh Shewale, Joshua Fisher, Babatunde Osokoya, Vasiliki Kalogianni, Kruthika Ramamurthi, Afnan Mahmoud, Nora Anna Nagy, James David Alexander Wood, Akash Chowdbury, Amy Ackerley, Mickey Shah, Laura Kent, Laura Barkess, Rebecca Seaman, Laura Adams, Jen Assimakopoulos, Sophia Gkolomazou, Bella Giles, James David Alexander Wood, Amy Ackerley, Mickey Shah, Laura Kent, Julia Karwat, Reem Ibrahim, Laura Barkess, Anna Tunnicliff, Rebecca Seaman, Bella Giles, Rochelle Pierre, Catherine Sheehan, Yue Wu, Alice Paterson‐Brown, Daniel O'Neill, Farrah Akkouch, Amrinder Sayan, Khatra Adam, Jamie Gonzales, Thomas Chambers, Corinne Rimmer, Lucy Brown, Della Solichan, Karen Fong, Ebi Uchechukwu, Karen Burns, Steve Peters, Deborah Power, Helen Morris, Jane Winder, Rosendelle Soriano, Aileen Menzies, Julie Le Bas, Susanna Crayton, Hilary Thatcher, Katie Mcguire, Marta Blanco Cabana, Ahmed Osman, Clare Finney, Nicholas Turner, Caitlin Spooner, Conor Murtagh, Jenny Olsson, Marianette Axalan, Anna Broderick, Burt Vergara, Kevin O'Reilly, Benedicte Sjoflot, Hywel Garrard, Stephen Thompson, Abigail Pemberton, Julie Melville, Diane Daniel, Katrina Mullane, Bethany Suggitt, Clair Rainford, Rebecca Mills, Brenda Pimlott, Taylor Doherty Walls, Susan Hopkins, Kai Zai, Oluwafunmilayo Oyekan, Vishramb Mattadeen, Dagnija Panter, Laura Scott, Moe Kishima, Matthew Hancock, Richard Stewart, Emily A Russell, Charlotte Willis, Shilpi Sethi, Gokul Sagar Bailur, Kurun Kumar, Patricia Avila del Puerto, Teena Babu, Felicity Williams, Richard Ramsaran, Sreela Jonnada, Gareth Allen, Sam Hewitt, James Roe, James Shuttleworth, Richard Ramsaran, Jennifer Entwistle, Victoria Waugh, Katie Edwards, Faye Bowden, Sarah Louise Richardson, Vivian Pringle, Anna Sharpe, Helen McNamara, Grainne Garvey, Vani Bhageria, Joanna Gumley, Lucky Angashang, Laura Wilson, Mirza Anwar Ahmed Baig, Tom Bedwell, Nitish Upadhyay, Jonathan Collins, Helen Bull, Emily Rice, Mark Gallagher, Amy Hughes, Hannah Quigley, Sally Bell, Bethany Foster, Elin Barham, Anuradha Kurvey, Oliver Froud, Christopher Fine, Natasha Lawes, Rachel Hoyle, SydneyAwuor Omondi, Wendy Goddard, Janice Hartley, Stephen Duberley, Danica Aspin, Anuradha Kurvey, Oliver Froud, Sanjiv Sharma, Stephen Duberley, Janice Hartley, Danica Aspin, Rachel Hoyle, Wendy Goddard, Genevieve Mullins, Alexandra Gray‐Renfrew, Zarina Bibi, Natasha Lawes, Manab Haldar, Tammy Murray, Caroline Dickens, Precious Vasvi, Louise Wilcox, Ben Thompson, Prashanth Parvatha Reddy, Michael Jarvis, Dhruti Pandya, Kerry Starkey, Matthew Huniak, Moheyelden Salahelden, Mettha Wimalasundera, Nicholas Ronan, Sunita Gurung, Rachel Morris, Joseph Pick, Emma Cooper, Andrew Plews, Salman Islam, Nabeel Chowdhury, Yara Ahmed, Mark Higgins, Vinodkumar Changarangath, Michelle Davies, Minnie Gellamucho, Lucy Bailey, Sian Wisbey, Martin Booth, Maxine Owen, Simone Locker, Jane Delaney, Dominic Jesudoss, Alison Brown, Elizabeth Nicol, Kaylee Gauntlett, Kim Hulacka, Colum Slorach, Rachael Robertson, Thomas Aitken, Michael Pretswell, Antony Sanjiev Ratnasingham, Charles Wallis, Francesca Wing, Michele Poole, Alexandria Page, Isaac Brookman, Sophie Beverley, Louise Nimako, Ellen Jessup‐Dunton, Yu Shen, Rupert Lees, Gail Murphy, Harry Barnett, Andrew Kermode, Kristina Bull, Indhuja Rajkumar, Merlin James, Jane Harding, Manish Das, Julie Houghton, Catherine Kloppenborg, Samantha Weller, Lisa Clutterbuck, Sarah Davies, Sabba Aziz, Sarah Beckley, Sunil Chaurasia, Thomas Smith, Lauren Pout, Nicholas Smith, Hannah Winder, Jennifer Butler, Lizzie Ribey, Paul Bramley, Kate Gamble, Jane Booker, Anna Galvin, Alice Nicholson, Tamsin Gregory, Charlotte Dowson, Nicholas Yu, Liz Shenton, Kellie Butterfield, Ginny Clarke, Helen Henson, Lindsey Stephens, Lisa Armstrong, Marcela P. Vizcaychipi, Laura Martins, Jaime Carungcong, Kribashnie Nundlall, Florison Canlas, Emily Futter, Carina Bautista, Rhian Bull, Julie Logan, Alexandra Schookmeesters, Patricia Costa, Katharine Balfour, Patrizia Simonato, Ilhan Wardhere, Tamsyn Glover, Ben Wooldridge, Claudia Gardiner, Samuel Worsley, Penny Parsons, Camilla Stagg, Judy Shirley, Angela Day, Inderjit Atwal, Sundar. 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Quantitative Measurements of Codeine and Fentanyl on a Surface-Enhanced Raman-Active Pad
Molecules, 2019 The USA is in the midst of an opioid crisis that included over 60,000 overdose fatalities in 2017, mostly unintentional. This is due to excessive use of prescription opioids and the use of very strong synthetic opioids, such as fentanyl, mixed with ...
Chetan Shende, Amelia Farquharson, Carl Brouillette, Wayne Smith, Stuart Farquharson +4 more
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Frontiers in PharmacologyObjectivesCodeine, a prodrug used as an opioid agonist, is metabolized to the active product morphine by CYP2D6. This study aimed to establish physiologically based pharmacokinetic (PBPK) models of codeine and morphine and explore the influence of CYP2D6
Yujie Yang, Xiqian Zhang, Yirong Wang, Heng Xi, Min Xu, Liang Zheng +5 more
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The Efficacy of Peripheral Opioid Antagonists in Opioid-Induced Constipation and Postoperative Ileus: A Systematic Review of the Literature. [PDF]
, 2017 Opioid-induced constipation has a negative impact on quality of life for patients with chronic pain and can affect more than a third of patients. A related but separate entity is postoperative ileus, which is an abnormal pattern of gastrointestinal ...
Baratta, Jaime L., Grant, Alexander E., McNulty, Stephen E., Schwenk, Eric S., Torjman, Marc C., Viscusi, Eugene R. +5 more
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Drug Use on Mont Blanc: A Study Using Automated Urine Collection [PDF]
, 2016 Mont Blanc, the summit of Western Europe, is a popular but demanding high-altitude ascent. Drug use is thought to be widespread among climbers attempting this summit, not only to prevent altitude illnesses, but also to boost physical and/or psychological
Botre', Francesco, Bouzat, Pierre, Buisson, Corinne, de la Torre, Xavier, Kérivel, Patricia, Lasne, Françoise, Mazzarino, Monica, Méchin, Nathalie, Robach, Paul, Roustit, Matthieu, Trebes, Gilles +10 more
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Intra-Arterial, but Not Intrathecal, Baclofen and Codeine Attenuates Cough in the Cat [PDF]
, 2021 Wendy L. Olsen, Melanie J. Rose, Frank J. Golder, Cheng Wang, Julie C. Hammond, Donald C. Bolser +5 more
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Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes +5 more
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BMC Veterinary Research, 2022 Background In humans, codeine is a commonly prescribed analgesic that produces its therapeutic effect largely through metabolism to morphine. In some species, analgesic effects of morphine have also been attributed to the morphine-6-glucuronide (M6G ...
Heather K. Knych, Kristen Stucker, Sophie R. Gretler, Philip H. Kass, Daniel S. McKemie +4 more
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Spatial Concentration of Opioid Overdose Deaths in Indianapolis: An Application of the Law of Crime Concentration at Place to a Public Health Epidemic [PDF]
, 2019 The law of crime concentration at place has become a criminological axiom and the foundation for one of the strongest evidence-based policing strategies to date.
Carter, Jeremy G., Mohler, George, Ray, Bradley +2 more
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Journal of Pharmacy & Pharmaceutical Sciences, 2018 PURPOSE Codeine containing medicines can carry a number of health risks associated with the increase in reported misuse and dependence, however they are still readily available over the counter (OTC) in many countries.
J. Wells, M. Bergin, M. Van Hout, Pádraig McGuinness, Jaco De Pleissisc, E. Rich, S. Dada, Richard Wells, M. Gooney +8 more
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