Results 231 to 240 of about 69,317 (259)

Release factor competition is equivalent at strong and weakly suppressed nonsense codons

Molecular and General Genetics MGG, 1988
We have compared the competition between strong or weak suppressor tRNAs and translational release factors (RF) at nonsense codons in the lacI gene of Escherichia coli. Using the F'lacIZ fusions developed by Miller and coworkers, UAG, UAA, and UGA codons at positions 189 and 220 were efficiently suppressed by plasmid-borne tRNA(trp) suppressors cognate
R, Martin, M, Hearn, P, Jenny, J, Gallant   +3 more
openaire   +2 more sources

Reversion of trpA nonsense mutations by deletion of the chain-termination codons

Biochimie, 1989
This paper describes a novel mechanism for reversion of nonsense mutations in the trpA gene of Escherichia coli. This mechanism, deletion of the nonsense codon, was discovered in the course of selecting for missense revertants of trpA(UGA211) and for catalytically active tryptophan synthetase alpha chain revertants of trpA(UAA234) and trpA(UAG234 ...
S D, Tucker, E J, Murgola, K A, Hijazi
openaire   +2 more sources

Orientation of Nonsense Codons on the Genetic Map of the Lac Operon

Science, 1967
Intracodon recombination is used to orient the nonsense codons UGA, UAG, and UAA on the genetic map of the (lactose) lac operon of Escherichia coli . The 5′-end of these triplets is toward the operator end of the operon.
openaire   +2 more sources

The effect of nonsense codons on splicing: a genomic analysis.

RNA (New York, N.Y.), 2003
The phenomenon of nonsense-associated altered splicing raises the possibility that the recognition of in-frame nonsense codons is used generally for exon identification during pre-mRNA splicing. However, nonsense codon frequencies in pseudo exons and in regions flanking 5' splice sites are no greater than that expected by chance, arguing against the ...
Xiang, Zhang, James, Lee, Lawrence A, Chasin   +2 more
openaire   +1 more source

Nonsense-mediated RNA decay: an emerging modulator of malignancy

Nature Reviews Cancer, 2022
Kun Tan, Miles F Wilkinson
exaly  

Engineered tRNAs suppress nonsense mutations in cells and in vivo

Nature, 2023
Nikhil Bharti, Marcos Davyt, Disha Joshi
exaly  

Nonsense Codon

2001
openaire   +2 more sources

Quality and quantity control of gene expression by nonsense-mediated mRNA decay

Nature Reviews Molecular Cell Biology, 2019
Tatsuaki Kurosaki, Keita Miyoshi, Lynne E Maquat   +2 more
exaly  

Early nonsense: mRNA decay solves a translational problem

Nature Reviews Molecular Cell Biology, 2006
Nadia Amrani, Matthew S Sachs, Allan Jacobson   +2 more
exaly  

Nonsense Codon

2008
openaire   +1 more source