Results 211 to 220 of about 95,678 (274)
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 942-952, April 2026.Pharmacogenomic research has historically focused on individuals of European ancestry, leading to the underrepresentation of genetic variants common in non‐European populations. This bias is exemplified by CYP3A5*6, a functionally consequential variant common in individuals of African ancestry (MAF: 11–19%) but virtually absent in Europeans (MAF: 0.15%)
Amar D. Levens +10 more
wiley +1 more source
Clinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.ABSTRACT Objective The objective of this review is to evaluate the existing literature on the regenerative potential of recombinant amelogenin, with a particular emphasis on the biological activity, synthesis, and delivery systems relevant to periodontal regeneration.
Jie Dan Denny Luo +4 more
wiley +1 more source
Codon bias and gene expression of mitochondrial ND2 gene in chordates. [PDF]
Bioinformation, 2015 Uddin A +3 more
europepmc +1 more source
Ecology and Evolution, Volume 16, Issue 4, April 2026.A newly generated large‐scale molecular phylogeny of true ladybirds (Coccinellini) clarifies their evolutionary relationships and supports a boreotropical origin in the Paleocene, with multiple independent southward dispersals. Ancestral diet reconstructions suggest an initial specialization on aphids, followed by expansions in host range and ...
Romain Nattier +10 more
wiley +1 more source
Ecology and Evolution, Volume 16, Issue 4, April 2026.This study reveals how ecological disturbances reshape the structure and function of soil bacterial communities in kauri forests, which are critical for ecosystem resilience. By linking disturbance regimes to shifts in bacterial diversity and functional capacity, it highlights the wider effects of ecosystem disturbance on soil ecological function ...
Alexa K. Byers +3 more
wiley +1 more source
Ecology and Evolution, Volume 16, Issue 4, April 2026.The Roridulaceae–Sarraceniaceae clade exhibits strikingly divergent carnivorous strategies, providing a framework to examine how trophic shifts influence plastid genome evolution. Comparative plastome analyses reveal recurrent ndh gene disruption across species, while Roridula gorgonias shows pronounced genomic restructuring, including elevated ...
Shengxin Chang +4 more
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.ABSTRACT Background Myofibrillar myopathies (MFM) form a large group of clinically and genetically heterogeneous protein aggregate diseases. We investigated whether a novel quantitative MRI protocol can reveal new aspects of structural and biochemical muscle pathology in three classic MFM subtypes.
Claudius S. Mathy +15 more
wiley +1 more source
Selection of functional 2A sequences within foot-and-mouth disease virus; requirements for the NPGP motif with a distinct codon bias. [PDF]
RNA, 2018 Kjær J, Belsham GJ.
europepmc +1 more source
Nanobody‐Mediated c‐MYC Degradation Inhibits Tumor Cell Progression
MedComm, Volume 7, Issue 4, April 2026.A cell‐permeable nanobody strategy was developed to target the intrinsically disordered oncoprotein c‐MYC. A synthetic nanobody, M4, binds the central PEST region of c‐MYC (241–263) and promotes c‐MYC degradation by enhancing Thr58 phosphorylation. Conjugation of M4 to a cell‐penetrating peptide (CPP) generates CPM4, which efficiently accumulates in ...
Yuanyuan Xue +7 more
wiley +1 more source