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Mitochondrial Genome of <i>Abramis brama orientalis</i> Reveals Dominant Role of Natural Selection over Mutation Pressure in Shaping Codon Usage Bias in Leuciscinae Fishes. [PDF]
Animals (Basel)Hao CL +8 more
europepmc +1 more source
Ecology and Evolution, Volume 16, Issue 5, May 2026.Here, we de novo assembled the chloroplast genomes of Ranunculus arvensis and Ranunculus laetus, providing comprehensive comparative analysis with 21 congeners. The genomes exhibited conserved quadripartite structures with no major rearrangements, though lineage‐specific variations in atpH position were detected in two species.
Hui Li +10 more
wiley +1 more source
Mapping the inter- and intra-genic codon-usage landscape in <i>Homo sapiens</i>. [PDF]
NAR Genom BioinformArshad M +5 more
europepmc +1 more source
Comparative Codon Usage Bias of CD2AP and BACH2 Across 49 Vertebrates: Implications for Porcine Macrophage Immunity in <i>Mycoplasma hyopneumoniae</i> Infection. [PDF]
Biology (Basel)Li W +8 more
europepmc +1 more source
Analysis of Codon Usage Bias Between Entomopathogenic Fungus <i>Ophiocordyceps sinensis</i> and Its Host, <i>Thitarodes xiaojinensis</i>. [PDF]
Biology (Basel)Yan J +7 more
europepmc +1 more source
Molecular Biology Reports, 2021 Codon usage bias is the preferential or non-random use of synonymous codons, a ubiquitous phenomenon observed in bacteria, plants and animals. Different species have consistent and characteristic codon biases. Codon bias varies not only with species, family or group within kingdom, but also between the genes within an organism.
Sujatha Thankeswaran Parvathy +2 more
exaly +3 more sources
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Annual Review of Genetics, 2008
In a wide variety of organisms, synonymous codons are used with different frequencies, a phenomenon known as codon bias. Population genetic studies have shown that synonymous sites are under weak selection and that codon bias is maintained by a balance between selection, mutation, and genetic drift.
Ruth Hershberg, Dmitri A Petrov
exaly +3 more sources
In a wide variety of organisms, synonymous codons are used with different frequencies, a phenomenon known as codon bias. Population genetic studies have shown that synonymous sites are under weak selection and that codon bias is maintained by a balance between selection, mutation, and genetic drift.
Ruth Hershberg, Dmitri A Petrov
exaly +3 more sources
Codon bias and gene expression [PDF]
FEBS Letters, 1991 The frequencies with which individual synonymous codons are used to code their cognate amino acids is quite variable from genome to genome and within genomes, from gene to gene. One particularly well documented codon bias is that associated with highly expressed genes in bacteria as well as in yeast; this is the so‐called major codon bias.
exaly +3 more sources
Codon Usage Bias: An Endless Tale
Journal of Molecular Evolution, 2021Since the genetic code is degenerate, several codons are translated to the same amino acid. Although these triplets were historically considered to be "synonymous" and therefore expected to be used at rather equal frequencies in all genomes, we now know that this is not the case. Indeed, since several coding sequences were obtained in the late '70s and
Andrés Iriarte +2 more
openaire +2 more sources
Relative Codon Adaptation Index, a Sensitive Measure of Codon Usage Bias
Evolutionary Bioinformatics, 2010 We propose a simple, sensitive measure of synonymous codon usage bias, the Relative Codon Adaptation Index (rCAI), as a way to discriminate better between highly biased and unbiased regions, compared with the widely used Codon Adaptation Index (CAI). CAI is a geometric mean of the relative usage of codons in a gene, and is calculated using the codon ...
Soohyun Lee, Changwon Kang
exaly +5 more sources