Results 121 to 130 of about 18,552 (255)
We integrated short‐read and long‐read RNA‐seq data from cochlear tissues of echolocating and non‐echolocating bats to disentangle transcriptional and post‐transcriptional regulation. Echolocating bats showed neural‐function enrichment among differentially expressed genes, while alternatively spliced genes were linked to epigenetic regulation. Overlaps
Jianyu Wu +3 more
wiley +1 more source
Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu +5 more
wiley +1 more source
Transcriptomics Unveil Dsx1 as a Critical Regulator in Sexual Dimorphism of Crustaceans
Sexually dimorphic traits are involved in reproductive competition and are shaped by sex‐biased gene expression. This study identifies Dsx1 as a key male‐biased gene in Morinoia aosen and demonstrates through RNA interference that its disruption feminizes male‐specific T3 leg structures.
Yan Tong +8 more
wiley +1 more source
Female‐Biased Sexual Size Dimorphism and Its Potential Causes in Hairy‐Winged Bats
Based on the integration of molecular genetics, traditional and geometric morphology, and acoustic characteristics of hairy‐winged bats (a species that was historically misclassified into two species due to extreme craniodental divergence between the sexes) in multiple regions of China, we quantified the sexual size dimorphism (SSD) between males and ...
Yang Yue +7 more
wiley +1 more source
Genomic Assessment of Reintroduced African Wild Dogs Informs Conservation Translocations
Few reintroduction and translocation programs incorporate genomic assessments into management planning, despite ongoing debate over how founder individuals should be selected. Here, we assess the genomic composition of reintroduced African wild dog (Lycaon pictus) populations in private reserves in South Africa, comparing them with a free‐roaming ...
Michou Weimar +4 more
wiley +1 more source
ABSTRACT Epidermolysis bullosa (EB) is an inherited mechanobullous genodermatosis caused by a mutation in genes encoding proteins integral to skin integrity. Premature termination codon readthrough therapies, such as gentamicin, have promise in facilitating full‐length protein expression in patients with EB.
Kelvin Truong +4 more
wiley +1 more source
Clinical manifestations of dual‐gene variants in retinitis pigmentosa
Abstract Purpose Retinitis pigmentosa (RP) is an inherited retinal disease (IRD), whereby each affected individual typically harbours pathogenic variants in a single causative gene, yet the disorder exhibits marked genetic heterogeneity, with more than 100 genes reported to underlie RP.
Lasse Wolfram +11 more
wiley +1 more source
Codon Usage Bias Analysis of Chloroplast Genomes in Six Cucurbitaceae Species. [PDF]
Xia Y, Huang Z.
europepmc +1 more source
Chronic traumatic encephalopathy in a neuropathologically confirmed Creutzfeldt–Jakob disease cohort
Systematic neuropathological screening of 212 patients with Creutzfeldt–Jakob disease (55% women) identified chronic traumatic encephalopathy in three cases (1.4%), all men with a history of contact sports. These findings represent the first neuropathologically confirmed chronic traumatic encephalopathy cases reported in Spain.
Lluc Bertran +13 more
wiley +1 more source

