Results 131 to 140 of about 18,552 (255)

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

British Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier, David Spähn, David Arturo Juarez Lopez, Judith L. Nono, Judith Seigner, Lisa Jacob, Siegfried Ussar, Robert Lukowski, Andreas L. Birkenfeld, Gencer Sancar   +9 more
wiley   +1 more source

Comparative Chloroplast Genomics, Codon Usage Bias, and Phylogenetic Placement of <i>Euonymus alatus</i>. [PDF]

Curr Issues Mol Biol
Zhao Y, Kong W, Huang Y, Zhang R, Qian C.   +4 more
europepmc   +1 more source

Unravelling the phylogeny of armadillos and their kin (Mammalia, Xenarthra, Cingulata) combining morphological, molecular, and stratigraphic data

Cladistics, EarlyView.
Abstract Cingulata, a major lineage of Xenarthra, comprises extinct and extant armoured placental mammals that diversified throughout the Cenozoic. Despite extensive study, phylogenetic hypotheses based on morphological and molecular data remain incongruent, and no total evidence analysis has been conducted. Here, we integrate the largest morphological
Daniel M. Casali, Mariela C. Castro, Martin R. Ciancio, Timothy J. Gaudin, Jeremy L. Bramblett, Alberto Boscaini, Fernando A. Perini, Max C. Langer   +7 more
wiley   +1 more source

Genus- and host-associated codon usage bias patterns in coronavirus spike genes. [PDF]

PLoS One
Chew JJ, Ng CH.
europepmc   +1 more source

Integrative phylogenomics uncovers hidden diversity and repeated cave colonizations in Dinaric pseudoscorpions

Cladistics, EarlyView.
Abstract Subterranean ecosystems harbour exceptional biodiversity shaped by adaptation to extreme environments, yet remain poorly explored. Cave organisms, restricted to small, isolated populations, are extinction‐prone, making integrative species delimitation essential for biodiversity assessment and conservation.
Dora Hlebec, Alba Enguídanos García, Marita Machata, Miquel A. Arnedo   +3 more
wiley   +1 more source

Codon usage bias and molecular evolution of <i>Dnajc15</i> across avian lineages. [PDF]

Front Genet
Zhou Z, Yang J, Dissanayake DSB, Schwanz L, Georges A, Xiong L.   +5 more
europepmc   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Analysis of Codon Usage Bias in the <i>Streptococcus pneumoniae</i> Pneumolysin Gene. [PDF]

Can J Infect Dis Med Microbiol
Tan X, Zhou H, Jiang J, Lu Y, Lu J, Shen W.   +5 more
europepmc   +1 more source

The trimeric Shu complex in C. elegans is an ATPase that remodels RAD51 filaments in the homologous recombination‐associated DNA damage response

The FEBS Journal, EarlyView.
The C. elegans Shu complex (RFS‐1/RIP‐1/SWS‐1) is a DNA‐dependent ATPase that regulates RAD‐51 filaments during homologous recombination. The trimer preferentially binds 5′‐exposed DNA, remodels RAD‐51 filaments via ATP hydrolysis, and stabilizes filaments through ATP binding.
Sam Siu Hang Chu, Guangxin Xing, Kichang Paik, Anton Gartner, Hong Ling   +4 more
wiley   +1 more source

Comparative chloroplast genomics reveals codon usage bias, simple sequence repeat dynamics, and phylogenomic relationships in Urticaceae. [PDF]

Front Plant Sci
Gao F, Fan W, Wang Z, Smagghe G, Riaz A, Xue Y, Li D, Gosai S, Gai Y.   +8 more
europepmc   +1 more source