Abstract Lung cancer is the leading cause of global cancer‐related morbidity and mortality, with tobacco smoking as its strongest risk factor. Nuclear factor erythroid 2‐related factor 2 (NRF2) is a redox‐regulated transcription factor frequently dysregulated in non‐small cell lung cancer (NSCLC), leading to aggressive disease and resistance to therapy.
Jouni Härkönen +14 more
wiley +1 more source
Natural Selection as the Primary Driver of Codon Usage Bias in the Mitochondrial Genomes of Three <i>Medicago</i> Species. [PDF]
Shen Y +5 more
europepmc +1 more source
Abstract The genus Citrus is characterized by a reticulate evolutionary history with frequent hybridization, making it an intriguing subject for genome evolution investigation. Citrus changshan‐huyou Y. B. Chang (Huyou) is a unique landrace first discovered in Zhejiang Province, China, with premium fruit quality.
Zhanghui Zeng +14 more
wiley +1 more source
Comparative Genomics of <i>Triticum, Secale,</i> and <i>Triticale</i>: Codon Usage Bias in Chloroplast Genomes and Its Implications for Evolution and Genetic Engineering. [PDF]
Tian T, Zhang Y, Du W, Wang Z.
europepmc +1 more source
Cell-type-specific profiling of alternative translation identifies regulated protein isoform variation in the mouse brain [PDF]
Dalal, Jasbir S +12 more
core +1 more source
Following maximal surgery when feasible, management of adult patients with isocitrate dehydrogenase (IDH)‐mutant glioma is complex and should be considered in a neuro‐oncology multidisciplinary context balancing disease control versus potential treatment‐associated toxicities. Options include continued surveillance, radiation therapy, chemotherapy, and/
Mark B. Pinkham +7 more
wiley +1 more source
Single‐Injection Multi‐Omics Analysis by Direct Infusion Mass Spectrometry
A high‐throughput direct infusion mass spectrometry platform, enabled by gas‐phase ion mobility separation, supports single‐injection analysis of peptides, polar metabolites, and lipids. Coupled with custom software, it identified ∽1,300 proteins and ∽600 metabolites in ∽4.3 minutes per sample, and demonstrated broad utility in macrophage polarization ...
Yuming Jiang +6 more
wiley +2 more sources
Comparative Chloroplast Genomics and Codon Usage Bias Analysis in <i>Hevea</i> Genus. [PDF]
Yang Y +12 more
europepmc +1 more source
ABSTRACT Alnus glutinosa is one of only three lineages within the order Fagales capable of establishing root nodule symbiosis (RNS). Although a fragmented genome assembly of A. glutinosa was previously available, its limited quality, combined with the lack of comprehensive transcriptomic resources, has constrained in‐depth comparative and functional ...
Zijian Liu +11 more
wiley +1 more source
Characterization of the complete chloroplast genome and comparative analysis of the phylogeny and codon usage bias of three Yunnan wild rice species. [PDF]
Li R +12 more
europepmc +1 more source

