Results 41 to 50 of about 36,066 (191)
Evolution of codon usage bias in Drosophila [PDF]
Proceedings of the National Academy of Sciences, 1997 We first review what is known about patterns of codon usage bias inDrosophilaand make the following points: (i)Drosophilagenes are as biased or more biased than those in microorganisms. (ii) The level of bias of genes and even the particular pattern of codon bias can remain phylogenetically invariant for very long periods of evolution.
J R, Powell, E N, Moriyama
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Relationship between amino acid composition and gene expression in the mouse genome [PDF]
, 2011 Background Codon bias is a phenomenon that refers to the differences in the frequencies of synonymous codons among different genes. In many organisms, natural selection is considered to be a cause of codon bias because codon usage in highly expressed ...
Kazuharu Misawa, Reiko F Kikuno
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Codon usage bias amongst plant viruses
Archives of Virology, 2003 An internet database (DPVweb) was established containing details of all sequences of viruses, viroids and satellites of plants that are complete or that contain at least one complete gene (n>4600). The start and end positions of each feature (genes, non-translated regions etc) were recorded and checked for accuracy.
Adams, M. J., Antoniw, J. F.
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Frontiers in Microbiology, 2016 Codon usage bias, as a combined interplay from mutation and selection, has been intensively studied in Escherichia coli. However, codon usage analysis in an E. coli pangenome remains unexplored and the relative importance of mutation and selection acting
Shixiang Sun +3 more
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Synthetic gene design - The rationale for codon optimization and implications for molecular pharming in plants. [PDF]
, 2017 Degeneracy in the genetic code allows multiple codon sequences to encode the same protein. Codon usage bias in genes is the term given to the preferred use of particular synonymous codons.
Ma, JK-C, Teh, AY-H, Webster, G
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Patterns of Codon Usage Bias in Silene latifolia [PDF]
Molecular Biology and Evolution, 2010 Patterns of codon usage bias (CUB) convey useful information about the selection on synonymous codons induced by gene expression and contribute to an understanding of substitution patterns observed at synonymous sites. They can also be informative about the distinctive evolutionary properties of sex chromosomes such as genetic degeneration of the Y ...
Qiu, Suo +3 more
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Codon usage bias and environmental adaptation in microbial organisms [PDF]
Molecular Genetics and Genomics, 2021 Abstract In each genome, synonymous codons are used with different frequencies; this general phenomenon is known as codon usage bias. It has been previously recognised that codon usage bias could affect the cellular fitness and might be associated with the ecology of microbial organisms.
Arella D., Dilucca M., Giansanti A.
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Codon usage bias reveals genomic adaptations to environmental conditions in an acidophilic consortium. [PDF]
PLoS ONE, 2018 The analysis of codon usage bias has been widely used to characterize different communities of microorganisms. In this context, the aim of this work was to study the codon usage bias in a natural consortium of five acidophilic bacteria used for biomining.
Andrew Hart +3 more
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Hidden patterns of codon usage bias across kingdoms [PDF]
Journal of The Royal Society Interface, 2018 AbstractThe genetic code is necessarily degenerate with 64 possible nucleotide triplets being translated into 20 amino acids. 18 out of the 20 amino acids are encoded by multiple synonymous codons. While synonymous codons are clearly equivalent in terms of the information they carry, it is now well established that they are used in a biased fashion ...
Yun Deng +4 more
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Enhanced effective codon numbers to understand codon usage bias [PDF]
Biosystems, 2019 AbstractCodon usage bias is a well recognized phenomenon but the relative influence of its major causes: G+C content, mutational biases, and selection, are often difficult to disentangle. This paper presents methods to calculate modified effective codon numbers that allow the investigation of the sources of codon bias and how genes or organisms have ...
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