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Synonymous codon usage in TTSuV2: analysis and comparison with TTSuV1. [PDF]
Two species of the DNA virus Torque teno sus virus (TTSuV), TTSuV1 and TTSuV2, have become widely distributed in pig-farming countries in recent years.
Zhicheng Zhang, Wei Dai, Dingzhen Dai
doaj +1 more source
Rapid divergence of codon usage patterns within the rice genome [PDF]
Background Synonymous codon usage varies widely between genomes, and also between genes within genomes. Although there is now a large body of data on variations in codon usage, it is still not clear if the observed patterns reflect the effects of ...
Donal A Hickey, Huai-Chun Wang
core +3 more sources
Quantifying Position-Dependent Codon Usage Bias [PDF]
Although the mapping of codon to amino acid is conserved across nearly all species, the frequency at which synonymous codons are used varies both between organisms and between genes from the same organism. This variation affects diverse cellular processes including protein expression, regulation, and folding. Here, we mathematically model an additional
Hockenberry, Adam J. +3 more
openaire +2 more sources
Translation elongation can control translation initiation on eukaryotic mRNAs [PDF]
Synonymous codons encode the same amino acid, but differ in other biophysical properties. The evolutionary selection of codons whose properties are optimal for a cell generates the phenomenon of codon bias.
Aitken +55 more
core +2 more sources
Codon-based indices for modeling gene expression and transcript evolution
Codon usage bias (CUB) refers to the phenomena that synonymous codons are used in different frequencies in most genes and organisms. The general assumption is that codon biases reflect a balance between mutational biases and natural selection.
Shir Bahiri-Elitzur, Tamir Tuller
doaj +1 more source
Compare the differences of synonymous codon usage between the two species within cardiovirus [PDF]
Background Cardioviruses are positive-strand RNA viruses in the Picornaviridae family that can cause enteric infection in rodents and also been detected at lower frequencies in other mammals such as pigs and human beings.
Wen-qian Liu +7 more
core +2 more sources
Patterns of Codon Usage Bias in Silene latifolia [PDF]
Patterns of codon usage bias (CUB) convey useful information about the selection on synonymous codons induced by gene expression and contribute to an understanding of substitution patterns observed at synonymous sites. They can also be informative about the distinctive evolutionary properties of sex chromosomes such as genetic degeneration of the Y ...
Qiu, Suo +3 more
openaire +3 more sources
Clustering of classical swine fever virus isolates by codon pair bias
Background The genetic code consists of non-random usage of synonymous codons for the same amino acids, termed codon bias or codon usage. Codon juxtaposition is also non-random, referred to as codon context bias or codon pair bias.
Leifer Immanuel +4 more
doaj +1 more source
Relationship between amino acid composition and gene expression in the mouse genome [PDF]
Background Codon bias is a phenomenon that refers to the differences in the frequencies of synonymous codons among different genes. In many organisms, natural selection is considered to be a cause of codon bias because codon usage in highly expressed ...
Kazuharu Misawa, Reiko F Kikuno
core +1 more source
Ribo-seq enlightens codon usage bias [PDF]
Codon usage is biased between lowly and highly expressed genes in a genome-specific manner. This universal bias has been well assessed in some unicellular species, but remains problematic to assess in more complex species. We propose a new method to compute codon usage bias based on genome wide translational data. A new technique based on sequencing of
Paulet, Damien +2 more
openaire +3 more sources

