Results 91 to 100 of about 8,297,474 (354)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Geometric properties of harmonic functions associated with the symmetric conjecture points and exponential function

AIMS Mathematics, 2020
In this paper, some classes of univalent harmonic functions are introduced by subordination, where the analytic parts of which are exponential starlike (or convex) functions with respect to the symmetric conjecture points.
Lina Ma, Shuhai Li, Huo Tang
doaj   +1 more source

Coefficient estimates for three generalized classes of meromorphic and bi-univalent functions

, 2015
In this paper, we introduce and investigate three interesting subclass $\Sigma_\vartheta^*(\lambda,\alpha)$, $\Sigma_\vartheta^B(\beta,\alpha)$ and $\tilde{\Sigma}_\vartheta^*(\alpha,\beta)$ of meromorphic and bi-univalent functions on $\Delta=\{z\in ...
Hai-Gen Xiao, Qing-Hua Xu
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

A reaction coefficient identification problem for fractional diffusion

, 2018
We analyze a reaction coefficient identification problem for the spectral fractional powers of a symmetric, coercive, linear, elliptic, second-order operator in a bounded domain $\Omega$.
Otarola, Enrique, Quyen, Tran Nhan Tam
core   +1 more source

Coefficient Estimates for Two New Subclasses of Biunivalent Functions with respect to Symmetric Points

, 2015
We introduce two subclasses of biunivalent functions and find estimates on the coefficients and for functions in these new subclasses. Also, consequences of the results are pointed out.
Ş. Altınkaya, S. Yalçın
semanticscholar   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Square function and maximal function estimates for operators beyond divergence form equations

, 2012
We prove square function estimates in $L_2$ for general operators of the form $B_1D_1+D_2B_2$, where $D_i$ are partially elliptic constant coefficient homogeneous first order self-adjoint differential operators with orthogonal ranges, and $B_i$ are ...
Rosén, Andreas
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Classes of analytic functions involving the q-Ruschweyh operator and q-Bernardi operator

AIMS Mathematics
In this paper, we introduced and studied two new classes of analytic functions using the concepts of subordination and q-calculus. We established inclusion relations for these q-classes and integral-preserving properties associated with the q-integral ...
Khadeejah Rasheed Alhindi, Khalid M. K. Alshammari, Huda Ali Aldweby   +2 more
doaj   +1 more source