Results 171 to 180 of about 7,015 (221)

Comparative study of the chemiluminescence of coelenterazine, coelenterazine-e and Cypridina luciferin with an experimental and theoretical approach

Journal of Photochemistry and Photobiology B: Biology, 2019
Imidazopyrazinone is a typical scaffold present in marine bioluminescence, in which thermal energy is converted into excitation energy in an enzyme-catalyzed reaction.
Carla M MAGALHÃES, , Luis Pinto da Silva   +2 more
exaly   +4 more sources

Conversion of dehydrocoelenterazine to coelenterazine in mammalian cells: Identification using cultured cells stably expressing coelenterazine-utilizing luciferase.

Biochemical and Biophysical Research Communications
Dehydrocoelenterazine (dCTZ) is a dehydrogenated form of coelenterazine (CTZ), which is well-known as the luciferin responsible for the bioluminescence reaction in marine organisms.
Satoshi Inouye, Sunao Hisada, Mitsuhiro Nakamura, Satoru Yokawa, Takahiro Suzuki   +4 more
semanticscholar   +3 more sources

Coelenterazine sulfotransferase from the luminous squid Watasenia scintillans.

Biochemical and Biophysical Research Communications
The squid Watasenia scintillans is a luminous marine organism that utilizes coelenterazine 2,6-disulfate (CTZ 2,6-SO3H) as its luminous substrate. CTZ 2,6-SO3H, a derivative of coelenterazine (CTZ), can be chemically synthesized by sulfating CTZ at its ...
Nowshin Farjana, Y. Mitani, Souichiro Kato, Shusei Kanie   +3 more
semanticscholar   +3 more sources

New red-shifted coelenterazine analogues with an extended electronic conjugation

Tetrahedron Letters, 2012
A new promising approach to the development of red-shifted coelenterazine analogues was described. In order to alter the photochemical properties of native coelenterazine, we have designed and synthesized analogues bearing a new electron-rich structure ...
Germano Giuliani, Paola Molinari, Andrea Cappelli   +2 more
exaly   +2 more sources

Antioxidative properties of natural coelenterazine and synthetic methyl coelenterazine in rat hepatocytes subjected to tert-butyl hydroperoxide-induced oxidative stress

Biochemical Pharmacology, 2000
Coelenterazine (CLZn; 3, 7-dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo++ +[1 ,2-a]pyrazin-3-one), the substrate for bioluminescence reactions in many marine animals, is endowed with high antioxidant properties.
Jacqueline Marchand-Brynaert, Jean-François Rees, F Baguet   +2 more
exaly   +2 more sources

Bioluminescent Properties of Semi-Synthetic Obelin and Aequorin Activated by Coelenterazine Analogues with Modifications of C-2, C-6, and C-8 Substituents

International Journal of Molecular Sciences, 2020
Ca2+-regulated photoproteins responsible for bioluminescence of a variety of marine organisms are single-chain globular proteins within the inner cavity of which the oxygenated coelenterazine, 2-hydroperoxycoelenterazine, is tightly bound. Alongside with
Elena V Eremeeva, Tianyu Jiang, Natalia P Malikova   +2 more
exaly   +2 more sources

Three Efficient Methods for Preparation of Coelenterazine Analogues

Chemistry - A European Journal, 2016
AbstractThe growing popularity of bioluminescent assays has highlighted the need for coelenterazine analogues possessing properties tuned for specific applications. However, the structural diversity of known coelenterazine analogues has been limited by current syntheses. Known routes for the preparation of coelenterazine analogues employ harsh reaction
Mary P Hall, Joel R Walker, Thomas Machleidt   +2 more
exaly   +3 more sources

Coelenterazine-dependent luciferases

Biochemistry (Moscow), 2015
Bioluminescence is a widespread natural phenomenon. Luminous organisms are found among bacteria, fungi, protozoa, coelenterates, worms, molluscs, insects, and fish. Studies on bioluminescent systems of various organisms have revealed an interesting feature - the mechanisms underlying visible light emission are considerably different in representatives ...
S V, Markova, E S, Vysotski
openaire   +2 more sources

Enzymatic sulfation of coelenterazine by human cytosolic aryl sulfotransferase SULT1A1: identification of coelenterazine C2-benzyl monosulfate by LC/ESI-TOF-MS.

Biochemical and Biophysical Research Communications - BBRC, 2023
Coelenterazine (CTZ) is known as a light-emitting source for the bioluminescence reaction in marine organisms. CTZ has two phenolic hydroxy groups at the C2-benzyl and C6-phenyl positions, and a keto-enol type hydroxy group at the C3-position in the core
S. Inouye, K. Matsuda, Mitsuhiro Nakamura   +2 more
semanticscholar   +1 more source

SYNTHESIS OF COELENTERAZINE

Organic Preparations and Procedures International, 2001
(2001). SYNTHESIS OF COELENTERAZINE. Organic Preparations and Procedures International: Vol. 33, No. 5, pp. 477-485.
Maciej Adamczyk, Donald D. Johnson, Phillip G. Mattingly, You Pan, Rajarathnam E. Reddy   +4 more
openaire   +1 more source