Results 91 to 100 of about 136,670 (296)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

ON CHEMISTRY AND FUNCTION OF COENZYME A [PDF]

, 1953
Fritz Lipmann
openalex   +1 more source

Spermidine reproduces the anti‐inflammatory effects of intermittent fasting and prevents urate and calcium pyrophosphate crystal‐induced inflammation

Arthritis &Rheumatology, Accepted Article.
Background Gout due to the formation of monosodium urate (MSU) crystals and calcium pyrophosphate (CPP) deposition disease are two major types of microcrystalline pathologies in adults. They are responsible for recurrent flares that rely on interleukin (IL)‐1β via activation of the NLRP3 inflammasome.
Chinh Nghia Pham, Florence Castelli, Flora Finet, Charles Leroy, Céline Chollet, Twinu Wilson Chirayath, Subhalaxmi Moitra, Mylène Zarka, Agnès Ostertag, François Brial, Christèle Combes, Augustin Latourte, Thomas Bardin, François Fenaille, Pascal Richette, Hang Korng Ea   +15 more
wiley   +1 more source

ON THE MECHANISM OF DEHYDROGENATION OF FATTY ACYL DERIVATIVES OF COENZYME A

, 1956
F.L. Crane, Shinsuke Mii, Jens G. Hauge, D. E. Green, Helmut Beinert   +4 more
openalex   +2 more sources

Effect of vepdegestrant, a PROTAC oestrogen receptor degrader, on dabigatran and rosuvastatin pharmacokinetics in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims To evaluate the effects of vepdegestrant, a PROteolysis TArgeting Chimera (PROTAC) oestrogen receptor degrader, on the pharmacokinetics of dabigatran (a P‐glycoprotein [P‐gp] substrate) and rosuvastatin (a breast cancer resistance protein [BCRP] substrate).
Derek Z. Yang, Li Zhou, Jennifer A. Winton, Kyle T. Matschke, Constantino Kantaridis, Kristine Doyle, Kimberly C. Lee, Naihan Chen, Yuanyuan Zhang, Weiwei Tan   +9 more
wiley   +1 more source

A Setup for Automatic Raman Measurements in High‐Throughput Experimentation

Biotechnology and Bioengineering, EarlyView.
Record Raman spectra in High‐Throughput Bioprocess Development. Measure eight samples of 50μL $50\,\mathrm{\mu L}$ fully automated. ABSTRACT High‐throughput (HT) experimentation is transforming biotechnology by enabling systematic exploration of complex multi‐dimensional experimental conditions.
Christoph Lange, Simon Seidel, Madeline Altmann, Daniel Stors, Annina Kemmer, Linda Cai, Stefan Born, Peter Neubauer, M. Nicolas Cruz Bournazou   +8 more
wiley   +1 more source

Efficacy and Engagement With an Immersive Virtual Learning Experience of the Citric Acid Cycle

Biochemistry and Molecular Biology Education, EarlyView.
ABSTRACT This randomized controlled trial assessed the comparative effectiveness of a biochemistry education program delivered through an immersive virtual reality (iVR) experience and traditional video‐based instruction. Undergraduate students enrolled in three nutrition courses from a large R1 American university participated (n = 95).
Bianca C. Braga, William Hurst, John Barrow, John Long, Gregory C. Shearer, Joanna K. Hodges, Olivia Lawler, Ravi Patel, Terry Schiavone, Travis D. Masterson   +9 more
wiley   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage

Chemistry &Biodiversity, EarlyView.
Graphical abstract of Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage ABSTRACT Antineoplastic agents can induce tissue damage through oxidative stress mechanisms. Doxorubicin, a widely used chemotherapeutic agent, has been shown to cause permanent damage to reproductive tissues.
Meltem Arıkan Malkoc, Serap Özer Yaman, Şafak Ersöz, Sevgi Kolaylı   +3 more
wiley   +1 more source

THE FUNCTION OF CYTIDINE COENZYMES IN THE BIOSYNTHESIS OF PHOSPHOLIPIDES

, 1956
Eugene P. Kennedy, Samuel B. Weiss
openalex   +1 more source