Results 101 to 110 of about 148,184 (310)

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Coenzyme B induced coordination of coenzyme M via its thiol group to Ni(I) of F-430 in active methyl-coenzyme M reductase

, 2003
Methyl-coenzyme M reductase (MCR) catalyzes the reaction of methyl-coenzyme M (CH3-S-CoM) with coenzyme B (HS-CoB) to methane and CoM-S-S-CoB. At the active site, it contains the nickel porphinoid F430, which has to be in the Ni(I) oxidation state for ...
Thauer, R. ; https://orcid.org/, Finazzo, C., Goenrich, M., Bauer, C., Thauer, RK, Schweiger, A, Jaun, B, Duin, E. C., Finazzo, C, Duin, E., Jaun, B., Harmer, J, Harmer, J., Van Doorslaer, S., Duin, EC, Goenrich, M, Thauer, R. K., Mahlert, F., Mahlert, F, Bauer, C, Schweiger, A., Van Doorslaer, S   +21 more
core   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Coenzyme Q10 Modulates Remodeling Possibly by Decreasing Angiotensin-Converting Enzyme in Patients with Acute Coronary Syndrome

Antioxidants, 2018
The study aims to examine the effects of coenzyme Q10, (a bioenergetic antioxidant), on the indexes of left ventricular remodeling, oxidative damage, and angiotensin-converting enzyme (ACE) level after acute myocardial infarction (AMI) with left ...
Ram B. Singh, Jan Fedacko, Viliam Mojto, Dominik Pella   +3 more
doaj   +1 more source

Coenzyme Q10: From Fact to Fiction

, 2015
There is a growing interest in coenzyme Q10 (CoQ10) and its involvement in many aspects of daily living including physical and mental health, energy, aging, stress, skin care and exercise. This book aims to highlight our current understanding of CoQ10 in
Hargreaves, April, Hargreaves, Iain
core  

First National Expanded Genomic Newborn Screening Program in Qatar; A Pilot Study, Doha‐Heidelberg Collaboration

American Journal of Medical Genetics Part A, EarlyView.
Reem Alsulaiman, Sarah Okashah, Radja Messai Badji, Fatemeh Abbaszadeh, Yaser Alsarraj, Rehab Ali Abdulrahman, Noora Shahbeck, Thalib Moideen, Reema El Hassan, Fatima Al‐Hamaydeh, Einas Alkuwari, Said Ismail, Hilal Al‐ Rifai, Ghassan Abdoh, Christian P. Schaaf, Georg Hoffmann, Saad Al‐Kaabi, Wadha Al‐Muftah, Tawfeg Ben‐Omran   +18 more
wiley   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Coenzyme Q10 effects in neurodegenerative disease

, 2009
Meredith Spindler1, M Flint Beal1,2, Claire Henchcliffe1,21Department of Neurology, 2Department of Neuroscience, Weill Medical College of Cornell University, New York, NY, USAAbstract: Coenzyme Q10 (CoQ10) is an essential cofactor in the mitochondrial ...
Claire Henchcliffe, Meredith Spindler, M Flint Beal   +2 more
core  

The Protective Effect of Coenzyme Q10 on the Renal Ischemia Reperfusion Induced Liver Injury

, 2019
Objectives:The aim of this study was to show the efficacy of coenzyme Q10, known as anti-oxidant with anti-inflammatory properties, in liver damage after renal ischemia-reperfusion (RIR).Materials and Methods:For this purpose, rats were divided into ...
ÖZGÜR, BERAT CEM, KARAKAYA KARABULUT, JALE, Gökhan Koca, Hatice Sürer, KOCA, GÖKHAN, Berat Cem Özgür, Jale Karakaya, Aylin Akbulut, Buğra Bilge Keseroğlu, Cem Nedim Yücetürk, Meliha Korkmaz, AKBULUT, AYLİN, KESEROĞLU, BİLGE BUĞRA, SÜRER, HATİCE, Elmas Öğüş, ÖĞÜŞ, ELMAS, YÜCETÜRK, CEM NEDIM, Nihat Yumuşak, KORKMAZ, MELİHA, YUMUŞAK, NİHAT   +19 more
core   +1 more source