Results 101 to 110 of about 136,670 (296)

5‐thiohistidine N‐acetyltransferase from Proteiniphilum saccharofermentans

open access: yesChemBioChem, Accepted Article.
Ovothiol A is a 5‐thiohistidine derivative biosynthesized by a broad range of prokaryotic and eukaryotic organisms. Its redox‐active mercaptoimidazole side chain is believed to protect cells from oxidative stress. The three enzymes that produce ovothiol A from histidine, cysteine, and S‐adenosyl methionine have been identified and characterized.
Cangsong Liao   +3 more
wiley   +1 more source

B12‐Cofactor Inactivation by Cobalt to Rhodium Mutation in Methylrhodibalamin: An Antivitamin B12 and Antibiotic

open access: yesChemistryEurope, EarlyView.
Replacement of cobalt in the organometallic B12‐cofactor methylcobalamin (MeCbl) by rhodium furnishes a structural mimic with a significantly stronger metal–carbon bond. This synthetically challenging formal metal‐mutation converts the naturally optimized biological methyl‐transfer catalyst MeCbl into a designed antivitamin B12, an inactivated B12 ...
Florian J. Widner   +8 more
wiley   +1 more source

A Method for the Purification of Coenzyme a from Yeast

open access: hybrid, 1953
Helmut Beinert   +6 more
openalex   +1 more source

Investigating the Mechanism of Antimycobacterial and Antiproliferative Activity of (E)‐N’‐Benzylidenepyrazine‐2‐Carbohydrazides and their Derivatives

open access: yesChemMedChem, EarlyView.
(E)‐N’‐benzylidenepyrazine‐2‐carbohydrazides with 2‐OH, 2,3‐diOH or 2,4‐diOH substitution exhibit good antimycobacterial or antiproliferative activity, and iron chelation similar to salicylaldehyde isonicotinoyl hydrazone (SIH). A series of 33 (E)‐N’‐benzylidenepyrazine‐2‐carbohydrazides and their derivatives were synthesized and tested for biological ...
Priam‐Amedeo Houngbedji   +14 more
wiley   +1 more source

The Promise and Pitfalls of Artificial Intelligence in the Evaluation of Synthetic “Greenness”

open access: yesChemSusChem, EarlyView.
Rapid rise of AI prompts a question whether it can be used to accelerate and standardize assessment of synthetic “greenness.” This perspective argues for the potential of such applications, although it also identifies several hurdles, like the need for extensive training or the creation of “ground truth” datasets.
Paweł Mateusz Nowak   +3 more
wiley   +1 more source

THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW)

open access: yesРазработка и регистрация лекарственных средств, 2019
In the human body, coenzyme Q10 is in the oxidized and reduced forms and can be found in every organ. The review describes modern HPLC methods of coenzyme Q10 analysis using electrochemical, spectrophotometric and mass spectrometric detectors.
V. I. Zozina   +3 more
doaj  

Biomimetic chloroplasts: Two‐phase microfluidic platforms with selective permeability for artificial photosynthesis

open access: yesDroplet, EarlyView.
We present a biomimetic chloroplast system that integrates light‐dependent and light‐independent reactions, reaction compartments, and selectively permeable interfaces using a biphasic microfluidic droplet platform. This system enables continuous substrate–product exchange, mitigating product inhibition and side reactions, thus enhancing reaction ...
Guanxiong Wang   +10 more
wiley   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai   +2 more
wiley   +1 more source

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