Results 251 to 260 of about 1,577,940 (309)

Rosuvastatin Upregulates RCOR1 to Repress C10ORF10 Transcription and Alleviate Oxidative Stress and Plaque Formation in Atherosclerosis

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 3, March 2026.
ABSTRACT Rosuvastatin (RVS) is an HMG‐CoA reductase inhibitor with lipid‐lowering properties. This study aims to investigate the role of RVS in plaque formation in atherosclerosis (AS) and its functional mechanism. ApoE−/− mice were fed a high‐fat diet to generate a mouse model of AS.
Xin Fu, Chuang Liu, Ya‐Li Chen, Jie‐Lin Qin, Ting‐Ting Wang, Shan‐Shan Fu   +5 more
wiley   +1 more source

NAD+ Enhanced on Hearing Recovery in Sudden Sensorineural Hearing Loss: Randomized Controlled Trial

The Laryngoscope, Volume 136, Issue 3, Page 1204-1214, March 2026.
This 2‐year, single‐center, double‐blind study with a small sample size compared NAD+ and control groups in a randomized controlled trial for sudden sensorineural hearing loss (SSNHL). Results showed that NAD+ led to better hearing improvement from 7 days to 3 months and a shorter average recovery time compared to the control group.
Minqian Gao, Yingting Guan, Xuejing Yue, Hao Bao, Qianwen Li, Yiqing Zheng, Yongkang Ou, Haidi Yang   +7 more
wiley   +1 more source

Uptake of Prochlorococcus‐derived metabolites by Alteromonas macleodii MIT1002 shows high levels of substrate specificity

Limnology and Oceanography Letters, Volume 11, Issue 2, March 2026.
Abstract Seawater contains small biomolecules, or metabolites, that are highly labile components of dissolved organic matter (DOM). Marine microbes interact by exchanging metabolites, thus shaping marine microbial ecology, DOM composition, and global carbon cycling.
Kathryn H. Halloran, Rogier Braakman, Allison Coe, Gretchen Swarr, Melissa C. Kido Soule, Sallie W. Chisholm, Elizabeth B. Kujawinski   +6 more
wiley   +1 more source

Enhanced PrrAB system activation and restricted farnesyl pyrophosphate diversion underlie high coenzyme Q₁₀ accumulation in <i>Rhodobacter sphaeroides</i> HY01. [PDF]

Synth Syst Biotechnol
He X, Wang H, Liang M, Wang W, Chen B, Li D, Zhang L, Tan GY.   +7 more
europepmc   +1 more source

Protein Lactylation in Cancer: Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 3, March 2026.
This schematic illustrates the central role of lactylation, a lactate‐derived posttranslational modification, in linking metabolic reprogramming to cancer progression and therapy resistance. At its core, lactylation modulates proteins, influenced by metabolic shifts and environmental factors.
Qianying Ouyang, Qianyu Hu, Caiqin Wang, Yizi He, Ruolan Zeng, Yajun Li, Chang Su, Guige Lu, Xueting Zhu, Ling Xiao, Hui Zhou   +10 more
wiley   +1 more source

Biochemical, histological, and immunohistochemical study on the therapeutic effects and mechanism of coenzyme Q₁₀ in type 2 diabetes mellitus. [PDF]

Res Pharm Sci
Khalil MI, Monfared AL, Mahmood HB.
europepmc   +1 more source

[Coenzyme Q (ubiquinone)].

Postepy biochemii, 1998
openaire   +1 more source

Unveiling the Probiotic Properties of Lacticaseibacillus paracasei UFTM 2.9 Through Probiogenomic Analysis

Molecular Nutrition &Food Research, Volume 70, Issue 6, 29 March 2026.
Probiogenomic and in vitro analyses revealed that Lacticaseibacillus paracasei UFTM 2.9 does not exhibit virulence determinants, produces inhibitory compounds against pathogenic bacteria, and possesses 170 genes associated with probiotics, which corroborates its metabolic versatility and potential for survival and functionality in the gastrointestinal ...
Bárbara R. Fonseca, Yasmin N. V. Sabino, Beatriz M. O. Rocha, Vasco A. C. Azevedo, Bertram Brenig, Siomar C. Soares, Leandro N. Lemos, Sheila C. P. D. Luquetti, Aline D. Paiva, Julliane D. Medeiros, Alessandra B. F. Machado   +10 more
wiley   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source