Results 261 to 270 of about 1,577,940 (309)

Ubiquinone (Coenzyme Q-10) Supplementation Influences Exercise-Induced Changes in Serum 25(OH)D₃ and the Methyl-Arginine Metabolites: A Double-Blind Randomized Controlled Trial. [PDF]

Antioxidants (Basel)
Mieszkowski J, Kochanowicz A, Brzezińska P, Kochanowicz M, Żołądkiewicz K, Stankiewicz B, Niespodziński B, Reczkowicz J, Kowalski K, Antosiewicz J.   +9 more
europepmc   +1 more source

Methylmalonic Acid, an Aging‐Associated Metabolite, Accelerates Intervertebral Disc Degeneration by Inducing Disc Vascularization via the CCL7/JAK2‐STAT3/VEGF Signaling Axis

Aging Cell, Volume 25, Issue 3, March 2026.
Our study reveals that elevated MMA in aged intervertebral discs promotes degeneration by activating the CCL7/JAK2‐STAT3/VEGF signaling axis, which drives pathological vascularization. Therapeutically, the VEGFR inhibitor lenvatinib attenuated this process, identifying disc vascularization as a promising therapeutic target for IVDD.
Yuanzhang Jin, Runtian Zhou, Xiaonan Wang, Haifeng Liu, Xiaofeng Zhao, Doudou Jing, Bin Zhao   +6 more
wiley   +1 more source

Prenatal and progressive coenzyme Q₁₀ administration to mitigate muscle dysfunction in mitochondrial disease. [PDF]

J Cachexia Sarcopenia Muscle
Hernández-Camacho JD, Vicente-García C, Ardila-García L, Padilla-Campos A, López-Lluch G, Santos-Ocaña C, Zammit PS, Carvajal JJ, Navas P, Fernández-Ayala DJM.   +9 more
europepmc   +1 more source

N‐Acetylglucosamine Selectively Attenuates Neuroinflammation in a Mouse Model of Mitochondrial Dysfunction

Acta Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim Mitochondrial dysfunction plays a central role in multiple neurodegenerative diseases, yet the temporal sequence of cellular events underlying neurodegeneration remains poorly defined. This study aimed to characterize the progression of neurodegeneration in a mouse model of fatal mitochondrial encephalopathy and to evaluate the therapeutic
Laura Jiménez‐Sánchez, Paula Ruiz‐López, Pilar González‐García, Janne Purhonen, Juan Manuel Martínez‐Gálvez, Sergio López‐Herrador, Julia Corral‐Sarasa, María Elena Díaz‐Casado, Carmen Venegas, Isaac Santos‐Pérez, Enrica Olivieri, Adriana L. Rojas, Luis Carlos López   +12 more
wiley   +1 more source

Association Between Unsaturated Fatty Acid Levels and Chronic Obstructive Pulmonary Disease: A Bidirectional Mendelian Randomization Study

The Clinical Respiratory Journal, Volume 20, Issue 3, March 2026.
Our MR analysis demonstrated that kinds of unsaturated fatty acids (UFAs) could be causal protective factors of chronic obstructive pulmonary disease (COPD). It reminded people to modify dietary nutrition, especially increasing the intake of UFAs to prevent COPD.
Shuai Jiang, Lili Lu, Xiaojun Wang, Xunxia Zhu, Xiaoyu Chen, Hung‐Chen Chang, Xuchao Gu, Fuzhi Yang, Xuanqi Liu, Xuelin Zhang, Xiaoyong Shen   +10 more
wiley   +1 more source

Coenzyme Q₁₀ as an Inhibitor of Effector Release from One-Electron-Reduced Bioreductive Anticancer Prodrugs. [PDF]

Molecules
Anderson RF, Qi W.
europepmc   +1 more source

Clinical Features, Biochemistry, Imaging, and Treatment Response in a Single-Center Cohort With Coenzyme Q₁₀ Biosynthesis Disorders. [PDF]

Neurol Genet
Wahedi A, Sudhakar S, Lam A, Ciancio JIR, Mills P, Gissen P, Gardham A, Kapadia J, Hassell J, Heales S, Rahman S.   +10 more
europepmc   +1 more source

The Scavenging Activity of Coenzyme Q₁₀ Plus a Nutritional Complex on Human Retinal Pigment Epithelial Cells. [PDF]

Int J Mol Sci
Hernandez M, Recalde S, Bezunartea J, Moreno-Orduña M, Belza I, Chas-Prat A, Perugini E, Garcia-Layana A, Fernández-Robredo P.   +8 more
europepmc   +1 more source

The Effects of a Novel Nutraceutical Composition Containing Coenzyme Q₁₀, Resveratrol, Extracts of <i>Ginkgo biloba</i> Leaf, Garlic Bulb, Red Yeast Rice, and Bovine Colostrum on Cardiac Dysfunction. [PDF]

Food Sci Nutr
Ma S, Chen M, Lai X, Gu Y, Hu, Guo Y, Yang L.   +6 more
europepmc   +1 more source

Circulating Glutathione Peroxidase-3 in Elderly-Association with Renal Function, Cardiovascular Mortality, and Impact of Selenium and Coenzyme Q₁₀ Supplementation. [PDF]

Antioxidants (Basel)
Alexander J, Aaseth JO, Schomburg L, Chillon TS, Larsson A, Alehagen U.   +5 more
europepmc   +1 more source