Results 171 to 180 of about 103,462 (335)

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

The FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero, Juan Luis Pacheco‐Garcia, Pavla Vankova, Dmitry Loginov, Isabel Quereda‐Moraleda, Jose Manuel Martin‐Garcia, Petr Man, Angel Luis Pey, Milagros Medina   +8 more
wiley   +1 more source

Effects of coenzyme q10 on lipid profile in streptozotocin induced diabetic rats [PDF]

Eurasian Journal of Veterinary Sciences
Aim: This research was carried out to evaluate the effects on lipid profile of Coenzyme Q10 in streptozotocin induced diabetic rats. Materials and Methods: In the study, 38 adult male Wistar Abino rats were divided into five groups.
Deniz Uluışık, Ercan Keskin, Yasemin Öznurlu, Tuğba Özaydın   +3 more
doaj  

Changes of plasma coenzyme Q₁₀levels in early infancy [PDF]

, 2004
Shuko Sato, Hirokazu Tsukahara, Yusei Ohshima, Naoko Ohta, Mayumi Uchiyama, Kyouichi Sekine, Tatsuo Uetake, Mitsufumi Mayumi   +7 more
openalex   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

Coenzyme Q ₁₀ and the exclusive club of diseases that show a limited response to treatment [PDF]

, 2021
Nadia Turton, Nathan L. Bowers, Sam Khajeh, Iain P. Hargreaves, Robert A. Heaton   +4 more
openalex   +1 more source

Real‐world clinical and laboratory changes after switching to two‐drug regimen in HIV‐suppressed individuals: 48 weeks and beyond

HIV Medicine, EarlyView.
Abstract Introduction Two‐drug regimens (2DRs) may reduce long‐term drug toxicities and drug‐drug interactions for people with HIV (PWH) on antiretroviral therapy (ART). This study evaluated clinical and laboratory outcomes in PWH who switched from standard ART to dolutegravir and lamivudine (DTG + 3TC) in real‐world settings.
Tommy Hing‐cheung Tang, Ruby Tsz‐shan Kwong, Phillip Chan, Kwok‐wai Lam, Helen Shuk‐ying Chan, Man‐yee Chu, Wilson Lam, Tak‐chiu Wu, Wai‐shing Leung, Sai‐kwong Yung, Wan‐man Ting, Annabel Kai‐tung Choy, Joe Lok‐fung Tung, Jason Ka‐wah Fong, Daniel Kai‐yeung Yeung, Man‐po Lee   +15 more
wiley   +1 more source

Effects of pH and Light Irradiation on Coenzyme Q₁₀Production Using Rhodobacter sphaeroides

, 2008
Soo-Kyoung Jeong, Van Dao, Ngyuen Kien, Joong-Kyun Kim   +3 more
openalex   +2 more sources

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Integration of heterologous 4-hydroxybenzoic acid transport proteins in Rhodobacter sphaeroides for enhancement of coenzyme Q₁₀production

, 2017
Feng Qi, Zou Limei, Xianzhang Jiang, Shaoli Cai, Mingliang Zhang, Xuebing Zhao, Jianzhong Huang   +6 more
openalex   +2 more sources

Dietary coenzyme Q₁₀ may improve the growth performance and antioxidant status in quails exposed to cold stress [PDF]

, 2020
Tahir Bayrıl, Fatih Akdemir, Hasan Akşit, Dilek Akşit   +3 more
openalex   +1 more source