Results 91 to 100 of about 32,845 (292)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

The Effect of Organophosphate Exposure on Neuronal Cell Coenzyme Q10 Status [PDF]

, 2020
Nadia Turton, Robert A. Heaton, Fahima Ismail, Sioned Roberts, Sian Nelder, Sue Phillips, Iain P. Hargreaves   +6 more
openalex   +1 more source

NADH‐Reductive Stress Induced by Dihydrolipoamide Dehydrogenase Activation Contributes to Cuproptosis

Advanced Science, EarlyView.
This study demonstrates a cuproptosis mechanism involving nicotinamide adenine dinucleotide (NADH)‐reductive stress in neural cells. Copper activates dihydrolipoamide dehydrogenase under mitochondrial pH, accumulating NADH. Copper also induces mitochondrial permeability transition pore opening, facilitating NADH translocation to the cytosol and ...
Si‐Yi Zhang, Xing‐Hua Ren, Cheng‐Hong Zhang, Zhan‐You Wang   +3 more
wiley   +1 more source

“Coenzyme Q10” (Coenzym Q10) [PDF]

IIC - International Review of Intellectual Property and Competition Law, 2016
openaire   +1 more source

Beyond Traditional RAFT Polymerization: Emerging Strategies and Future Perspectives; A Third Update

Advanced Science, EarlyView.
This review explores recent advances in the past five years for non‐traditional RAFT polymerization, focusing on new activation strategies, sustainable depolymerization, and integration with automated and AI‐driven synthesis. Together, these innovations advance polymer chemistry and reveal how the pieces of the non‐traditional RAFT puzzle are steadily ...
Vianna F. Jafari, James L. Grace, Jiajia Li, Joji Tanaka, Glen R. Jones, Athina Anastasaki, Wei You, Jian Zhu, Masami Kamigaito, Cyrille Boyer, Greg G. Qiao   +10 more
wiley   +1 more source

Apoptotic and proliferative processes in the small intestine of rats with type 2 diabetes mellitus after metformin and propionic acid treatment

Frontiers in Pharmacology
BackgroundPropionic acid (PA) is an intermediate product of metabolism of intestinal bacteria and may protect the intestinal barrier from disruption. The aim of the study was to investigate the apoptotic and proliferative processes in the small intestine
Larysa Natrus, Olha Lisakovska, Anton Smirnov, Yuliia Osadchuk, Yuliia Klys   +4 more
doaj   +1 more source

Dynamics of Vitamins and Phenols of Alchemilla subcrenata by Diurnal Variation of Temperature in October [PDF]

Journal of Stress Physiology & Biochemistry, 2016
Round-the-clock dynamics of phenols and vitamins В6, С, РР in the leaves of Alchemilla subcrenata with a glance of thermal change was shown. The maximum of content of phenols and vitamin С was observed at 6 a.m.
Zhivetev M.A., Rudikovskaya E.G., Dudareva L.V., Graskova I.A., Voinikov V.K.   +4 more
doaj  

Additional file 2 of Genome-wide identification and characterization of caffeoyl-coenzyme A O-methyltransferase genes related to the Fusarium head blight response in wheat

, 2021
Guang Yang, Wenqiu Pan, Ruoyu Zhang, Yan Pan, Qifan Guo, Weining Song, Weijun Zheng, Xiaojun Nie   +7 more
openalex   +1 more source

Systematic Metabolic Engineering and Model‐Guided Optimization for High‐Level Production of L‐Theanine From Xylose in Escherichia Coli

Advanced Science, EarlyView.
This study is pioneering in constructing the shortest known synthetic pathway for L‐theanine production from xylose within E coli. Through comprehensive metabolic engineering strategies, our engineered strain achieved the highest reported L‐theanine titer from xylose, with a titer of 95.42 g/L, and a yield of 0.55 g/g.
Haolin Han, Boyuan Xue, Guangqi Shan, Meng Meng, Shaojie Wang, Haijia Su   +5 more
wiley   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source