Results 101 to 110 of about 26,188 (302)

Understanding coenzyme Q

open access: yesPhysiological Reviews
Coenzyme Q (CoQ), also known as ubiquinone, comprises a benzoquinone head group and a long isoprenoid side chain. It is thus extremely hydrophobic and resides in membranes. It is best known for its complex function as an electron transporter in the mitochondrial electron transport chain (ETC) but is also required for several other crucial cellular ...
Ying Wang   +2 more
openaire   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

A Specific Process to Purify 2-Methyl-D-Erythritol-4-Phosphate Enzymatically Converted from D-Glyceraldehyde-3-Phosphate and Pyruvate

open access: yesNatural Product Communications, 2015
A one-pot enzymatic cascade was established to synthesize MEP, one of the key intermediates in the MEP terpenoid biosynthetic pathway. D-GAP and sodium pyruvate were converted to MEP in a reaction catalyzed by DXP synthase and DXP reductoisomerase (DXR ...
Shao-Qing Yang   +4 more
doaj   +1 more source

The Effects of Dietary Food Fortified with Vitamin B4 on Lipid Profiles in Serum and Liver Tissue [PDF]

open access: yes, 2010
The effects of dietary food fortified with vitamin B4 on lipid profiles in serum and liver tissue were studied. Rats were paired-fed a 0.25% vitamin B4 diet or a diet without vitamin B4 for 10 days.
Buang, Y. (Yohanes)
core  

Two approaches to the study of the origin of life. [PDF]

open access: yes, 2007
This paper compares two approaches that attempt to explain the origin of life, or biogenesis. The more established approach is one based on chemical principles, whereas a new, yet not widely known approach begins from a physical perspective. According to
A Bekker   +104 more
core   +4 more sources

Coenzyme Q. LX. Vitamin-Like Activity of Coenzyme Q.

open access: yesExperimental Biology and Medicine, 1965
SummaryVitamin-like activity for hexahydrocoenzyme Q4 in the dystrophic rabbit is demonstrated. This activity for a quinone member of the CoQ group is comparable to the activity of α-tocopherol and CoQ4-chromanol which has previously been demonstrated. By contrast, a sample of 2,3,5-trimethyl-6-phytylbenzoquinone, which was free of contamination with α-
J L, SMITH, H W, MOORE, K, FOLKERS
openaire   +2 more sources

Changes in lipids and medium- and long-chain fatty acids during the spontaneous fermentation of ripened pu-erh tea

open access: yesCurrent Research in Food Science
During the fermentation of ripened pu-erh tea (RPT), the composition of lipids and other compounds changes significantly. In this study, we conducted industrial fermentation of RPT and observed that the levels of water extract, tea polyphenols, free ...
Qiu-yue Chen   +13 more
doaj   +1 more source

A Novel Regulator of Activation-Induced Cytidine Deaminase/APOBECs in Immunity and Cancer: Schrödinger’s CATalytic Pocket

open access: yesFrontiers in Immunology, 2017
Activation-induced cytidine deaminase (AID) and its relative APOBEC3 cytidine deaminases boost immune response by mutating immune or viral genes. Because of their genome-mutating activities, AID/APOBECs are also drivers of tumorigenesis.
Mani Larijani, Justin J. King
doaj   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

open access: yesAnimal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou   +4 more
wiley   +1 more source

Hepatotoxicity of Nonesterified Fatty Acids to Dairy Cows: Pathophysiological Mechanisms and Prospective Solutions

open access: yesAnimal Research and One Health, EarlyView.
Unregulated inflammation increases non‐esterified fatty acids (NEFAs), and triggers multi‐pathway hepatocyte damage including oxidative stress, mitochondrial dysfunction, and metabolic disorders in dairy cows. ABSTRACT Circulating concentrations of nonesterified fatty acids (NEFAs) are elevated due to lipid mobilization from adipose tissue in ...
Siqing Mao   +12 more
wiley   +1 more source

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