Results 91 to 100 of about 14,378 (296)
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
BMEMat, EarlyView.Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy
BMEMat, EarlyView.This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma +9 more
wiley +1 more source
Synthetic coenzymes for in vitro selection of DNA enzymes.
, 2006 Includes bibliographical references (p. 233-243).Over the past 10 years a number of catalytically active single-stranded DNA molecules (deoxyribozymes) have been isolated from combinatorial libraries (pools) of randomized oligonucleotides.
Carranza, Dorn L.
core
Disappearing peaks in the nuclear magnetic resonance spectra of flavin coenzymes
, 1975 In alkaline deuterium oxide solution the N.M.R. spectra of flavin coenzymes exhibit selective broadening and eventual disappearance of the signals assigned to the flavin ring protons.
MD Fenn, PR Andrews
core +1 more source
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
BMEMat, EarlyView.Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
Original scientific paper Binding of coenzymes to yeast alcohol dehydrogenase
, 2009 : In this work, the binding of coenzymes to yeast alcohol dehydrogenase (EC 1.1.1.1) were investigated. The main criterions were the change in the standard free energies for individual reaction steps, the internal equilibrium constants and the overall ...
Julijan Kandrač, Mira Popović
core
Use of coenzymes I and II in interconversion of testosterone and androstenedione
, 1961 Adult male guinea pig liver and kidney homogenates were able to utilize triphosphopyridine nucleotide as well as diphosphopyridine nucleotide in the conversion of testosterone and androstenedione and the reduced coenzymes in the reverse reaction.
V. S. Raut +2 more
core +1 more source
Precision Chemistry for Protein Lysine Modification
Chemistry – A European Journal, EarlyView.Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley +1 more source
Chemistry – A European Journal, EarlyView.DFT calculations on porphyrin, corrin, and corphin complexes of cobalt, rhodium, iron, manganese, or nickel, and QM/MM calculations on enzyme models, explore the factors controlling the availably of super‐reduced metal(I) states. True metal(I) states are seen in corrin only for cobalt, in corphin only for nickel, and not at all in porphyrin.
Radu‐Ioan Onija +3 more
wiley +1 more source