Results 121 to 130 of about 86,596 (332)

Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage

open access: yesChemistry &Biodiversity, EarlyView.
Graphical abstract of Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage ABSTRACT Antineoplastic agents can induce tissue damage through oxidative stress mechanisms. Doxorubicin, a widely used chemotherapeutic agent, has been shown to cause permanent damage to reproductive tissues.
Meltem Arıkan Malkoc   +3 more
wiley   +1 more source

5‐Thiohistidine N‐Acetyltransferase from Proteiniphilum Saccharofermentans

open access: yesChemBioChem, EarlyView.
Proteiniphilum saccharofermentans, a Gram‐negative facultative anaerobe, produces an N‐acetyl transferase (5THNAT) that acetylates 5‐thiohistidine using acetyl‐CoA. This reaction competes with OvoC‐mediated Nπ‐methylation of the same substrate.
Cangsong Liao   +3 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Functional Analysis of Histidine‐Dependent Self‐Cleaving RNAs Obtained by In Vitro Selection

open access: yesChemBioChem, EarlyView.
Ribozymes can be nucleic acid medicines given their catalytic activity. We attempted to obtain functional RNAs that mimic ribonuclease A catalytic mechanisms. Functional RNAs with high histidine specificity were obtained, suggesting that histidine acts in active structure formation.
Nae Sakimoto   +8 more
wiley   +1 more source

Reaction Engineering of In Vitro Natural Product Biosynthesis: Challenges and Strategies

open access: yesChemBioChem, EarlyView.
The yield and turnover of in vitro natural product biosynthesis, and even its feasibility, are determined by intermolecular interactions. Reaction engineering allows to improve the performance of such complex biocatalytic systems. Natural products are widely used as pharmaceuticals and agrochemicals, or as active ingredients in food and cosmetics ...
Elsa Sánchez‐García   +2 more
wiley   +1 more source

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