Protein engineering of oxidoreductases utilizing nicotinamide-based coenzymes, with applications in synthetic biology [PDF]
Two natural nicotinamide-based coenzymes (NAD and NADP) are indispensably required by the vast majority of oxidoreductases for catabolism and anabolism, respectively.
Rui Huang +2 more
exaly +4 more sources
Coenzyme-protein interactions since early life [PDF]
Recent findings in protein evolution and peptide prebiotic plausibility have been setting the stage for reconsidering the role of peptides in the early stages of life’s origin.
Alma Carolina Sanchez Rocha +4 more
doaj +2 more sources
The content of riboflavin and its coenzymes forms in the brain of rats of different ages [PDF]
The content of total riboflavin and its coenzymes (FAD and FMN) in the brain homogenates of rats of different ages by means of fluorimetric ion exchange chromatography was determined. The experiment included 3 age groups of rats: 3 months, 10-12 months,
N. L. Fedorko +2 more
doaj +5 more sources
Ultra-rapid and high-titer biomanufacturing of trehalose 6-phosphate by an in vitro synthetic biology platform [PDF]
Trehalose 6-phosphate (T6P), often referred to as plant insulin, serves as a central signaling molecule that regulates carbon partitioning and sucrose flux in plants, thereby influencing key agronomic traits, such as grain yield and drought resilience ...
Bohua Liu +5 more
doaj +2 more sources
The Role of Coenzymes on Mercury (Hg2+) Bioremediation by Isolates Pseudomonas aeruginosa KHY2 and Klebsiella pneumonia KHY3 [PDF]
Mercury pollution is dangerous to health. Previous research was found two potential Gram-negative bacteria for mercury bioremediation, from gold mining in Central Kalimantan, Indonesia.
Liswara Neneng, Yohanes Edy Gunawan
doaj +3 more sources
Vitamin D(3) and methylenebisphosphonic acid in the correction of mineral metabolism disorders and bone remodeling associated with glucocorticoid-induced osteoporosis [PDF]
The study was aimed at evaluating therapeutic efficacy of vitamin D3 (VD3, 1000 IU/kg of b.w., 30 days) and sodium salt of methylenebisphosphonic acid (MBPA, 17 mg/kg of b.w., 30 days) monotherapies as well as their effect in combination in preventing ...
O. O. Lisakovska +5 more
doaj +1 more source
Plant productivity greatly relies on a flawless concerted function of the two photosystems (PS) in the chloroplast thylakoid membrane. While damage to PSII can be rapidly resolved, PSI repair is complex and time-consuming. A major threat to PSI integrity
Moritz Krämer, Hans-Henning Kunz
doaj +1 more source
IntroductionVitamin D3 (VD3) is a potent para/autocrine regulator and neurosteroid that can strongly influence nerve cell function and counteract the negative effects of glucocorticoid (GC) therapy.
Olha Lisakovska +8 more
doaj +1 more source
Background. The aim was to investigate the influence of propionic acid (PA) on the endoplasmic reticulum (ER), unfolded protein response (UPR) state, and astrocyte/microglia markers in rat ventromedial hypothalamus (VMH) after type 2 diabetes mellitus ...
Larysa V. Natrus +5 more
doaj +1 more source
Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes [PDF]
The search for affordable, green biocatalytic processes is a challenge for chemicals manufacture. Redox biotransformations are potentially attractive, but they rely on unstable and expensive nicotinamide coenzymes that have prevented their widespread ...
Nigel S. Scrutton (110351) +6 more
core +4 more sources

