Objectives. Recent prospective studies have found the associations between type 1 diabetes (T1D) and vitamin D deficiency. We investigated the role of vitamin D in the regulation of 25OHD-1α-hydroxylase (CYP27B1) and VDR expression in different tissues ...
Anna Mazanova +5 more
doaj +1 more source
Atherosclerosis and Coenzyme Q10 [PDF]
Atherosclerosis is the most common cause of cardiac deaths worldwide. Classically, atherosclerosis has been explained as a simple arterial lipid deposition with concomitant loss of vascular elasticity. Eventually, this condition can lead to consequent blood flow reduction through the affected vessel.
Juan M. Suárez-Rivero +10 more
openaire +3 more sources
NADH:ubiquinone reductase and succinate dehydrogenase activity in the liver of rats with acetaminophen-induced toxic hepatitis on the background of alimentary protein deficiency [PDF]
The ratio between the redox forms of the nicotinamide coenzymes and key enzymatic activity of the I and II respiratory chain complexes in the liver cells mitochondria of rats with acetaminophen-induced hepatitis under the conditions of alimentary ...
G. P. Kopylchuk, O. M. Voloshchuk
doaj +1 more source
Phototherapy of Brain Tumours Using a Fibre Optic Neurosystem
In this work, a new approach was tested to assess the cellular composition of tissues by time-resolved methods of fluorescence analysis of exogenous and endogenous fluorophores.
Yuliya Maklygina +4 more
doaj +1 more source
Alternative coenzymes for biocatalysis
Coenzymes are ubiquitous in Nature, assisting in enzyme-catalysed reactions. Several coenzymes, nicotinamides and flavins, have been known for close to a century, whereas variations of those organic molecules have more recently come to light. In general,
Guarneri, Alice +9 more
core +2 more sources
Vitamin Bs as Potent Anticancer Agents through MMP-2/9 Regulation
In recent years, the role of coenzymes, particularly those from the vitamin B group in modulating the activity of metalloenzymes has garnered significant attention in cancer treatment strategies.
Ha Vy Thi Vo, Namdoo Kim, Hyuck Jin Lee
doaj +1 more source
Determination of a method for extraction of coenzyme Q10 in human plasma: optimization of the use of surfactants and other variables [PDF]
Objective: To establish a routine for the extraction of the total levelsof CoQ10 in human plasma through the Ultra High Performance LiquidChromatography (UHPLC). Methods: Two extraction protocolswere tested: a) methanol: hexane and b) 1-propanol.
Claudia Cristina Ferreiro-Barros +2 more
doaj +2 more sources
Experimental preeclampsia development depends on vitamin D(3) status in female wistar rats [PDF]
Deficiency of vitamin D3 during pregnancy is a widespread challenge associated with increased risk of complications, particularly preeclampsia (PE), a serious condition characterized by hypertension with proteinuria.
I. V. Poladych +3 more
doaj +1 more source
Comparative values of liver nicotinamide nucleotide coenzymes, endocrine glands, and their relationships with production traits of diallel crossed beef bulls [PDF]
This investigation for the first time reports information on the correlation of various forms and ratios of nicotinamide nucleotide coenzymes in the liver tissue and endocrine glands weight with various production traits. Fifty-five inbred and line cross
Anwar-Afghan, Mohammad
core +6 more sources
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

