Results 51 to 60 of about 26,188 (302)

Group B vitamins: prospective for multidisciplinary application: A review

Consilium Medicum, 2023
Group B vitamins are used in various fields of medicine, most commonly in treating diseases of the peripheral and central nervous system, especially in treating pain. Group B vitamins are neurotropic agents; they play an essential role in the functioning
Liubov A. Kuzina, Gulnaz S. Kaishibaeva
doaj   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Genetic Studies of Sulfadiazine-resistant and Methionine-requiring \u3cem\u3eNeisseria\u3c/em\u3e Isolated From Clinical Material [PDF]

, 1967
Deoxyribonucleate (DNA) preparations were extracted from Neisseria meningitidis (four isolates from spinal fluid and blood) and N. gonorrhoeae strains, all of which were resistant to sulfadiazine upon primary isolation.
BROWN G. M., CATLIN B. W., CATLIN B. W., CATLIN B. W., CATLIN B. W., CAUTHEN S. E., DAVIS B. D., DAVIS B. D., DEMAIN A. L., DEMEREC M., E., DONALD I. J., DU VIGNEAUD V., W., EICKHOFF T. C., GRABOW W., HARRIS J. S., HATCH F. T., HOTCHKISS R. D., KAPLAN M. M., KATZEN H. M., KOHN H. I., LANDY M., LEDERBERG J., MILLAR J. W., OAKBERG E. F., PATO M. L., REYN A., REYN A., ROWBURY R. J., SICARD A. M., SINGER S., G., SMITH D. A., WILLCOX R. R., WINKLER K. C., WOLF B., WOODS D. D., WOODS D. D.   +35 more
core   +2 more sources

Coenzyme Q10 Deficiency [PDF]

Deutsches Ärzteblatt international, 2016
The prevalence of dyslipidemia is high. It is usually treated with statins which inhibit HMG-CoA reductase and also coenzyme Q10 synthesis. This may lead to muscle pain. The question whether coenzyme Q10 replacement treatment helps to improve these muscle symptoms has been evaluated in a prospective study.
openaire   +2 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Bio-Inspired Smart Nanoparticles in Enhanced Cancer Theranostics and Targeted Drug Delivery

Journal of Functional Biomaterials, 2022
Globally, a significant portion of deaths are caused by cancer.Compared with traditional treatment, nanotechnology offers new therapeutic options for cancer due to its ability to selectively target and control drug release.
Khushabu Gulia, Abija James, Sadanand Pandey, Kamal Dev, Deepak Kumar, Anuradha Sourirajan   +5 more
doaj   +1 more source

Effect of nitrous oxide on folate coenzyme distribution and de novo synthesis of thymidylate in human bone marrow cells [PDF]

, 1992
The effect of nitrous oxide on intracellular folate metabolism of the human bone marrow was studied in vitro. Bone marrow cells, obtained from healthy volunteers, were incubated with 5 × 10−8m-[3H]5-formyltetrahydrofolate (5-formylTHF) for 18 hr to label
Abels, J. (Lyanne), Ermens, A.A.M. (Anton), Lindemans, J. (Jan), Schoester, M. (Martijn)   +3 more
core   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

Advanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao, Jennifer Michel, Eline Lorer, Markus Weinmann, Jacques Le Gouis, Claire Léon, Sibille Perrochon, David Alvarez, Vincent Leemans, Iñaki Balanzategui Guijarro, Jordi Moya Laraño, Sara Sánchez Moreno, Symanczik Sarah, Waibel Matthias, Hervé Vanderschuren, Cécile Thonar, Pierre Delaplace, Dominique Van Der Straeten   +17 more
wiley   +1 more source

Nanoemulsion-directed growth of MOFs with versatile architectures for the heterogeneous regeneration of coenzymes

Nature Communications, 2022
Controlling the structure of hierarchical metal-organic frameworks via soft template remains a challenge. Here, the authors report a salt-assisted nanoemulsion-guided strategy to achieve continuous structure transition of hierarchical Zr-based MOFs.
Ke Li, Yucheng Zhao, Jian Yang, Jinlou Gu   +3 more
doaj   +1 more source