Results 51 to 60 of about 14,411 (293)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Vitamin Related Coenzymes [PDF]
, 2008 Bu ders notunda koenzim ve kofaktörlerle ilgili vitaminler, fonksiyonları, yapısal formülleri ve görev aldıkları reaksiyonlar verilmektedir.The lecture note contends vitamins which are related to coenzymes and cofactors, their functions, structural ...
ERKOC, FIGEN
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Binding of coenzymes to yeast alcohol dehydrogenase [PDF]
Journal of the Serbian Chemical Society, 2010 In this work, the binding of coenzymes to yeast alcohol dehydrogenase (EC 1.1.1.1) were investigated. The main criterions were the change in the standard free energies for individual reaction steps, the internal equilibrium constants and the overall ...
VLADIMIR LESKOVAC +4 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
Testing the content of vitamin A in dietary supplements
Journal of Education, Health and Sport, 2019 Vitamins in the human body perform regulatory functions, determine the development, health and physical performance of the body. Most of them are not synthesised in the body, therefore they must be supplied with food. They interact with enzymes, which is
Marcin Ślifirczyk +3 more
doaj +3 more sources
Experimental Biology and MedicineOur objective was to study the effect of vitamin D3 (VD) on hepatocellular oxidative-nitrosative stress and pro/anti-inflammatory cytokines in relation to nitric oxide (NO) formation and NO synthase (NOS) levels in type 2 diabetes mellitus (T2DM).
Ihor Shymanskyi +9 more
doaj +1 more source
B Vitamins and Their Roles in Gut Health
Microorganisms, 2022 B vitamins act as coenzymes in a myriad of cellular reactions. These include energy production, methyl donor generation, neurotransmitter synthesis, and immune functions.
Khandkar Shaharina Hossain +2 more
doaj +1 more source
C1 transfer enzymes and coenzymes linking methylotrophic bacteria and methanogenic Archaea [PDF]
, 1998 Methanogenic and sulfate-reducing Archaea are considered to have an energy metabolism involving C-1 transfer coenzymes and enzymes unique for this group of strictly anaerobic microorganisms.
Thauer, R. ; https://orcid.org/ +3 more
core +1 more source