Results 51 to 60 of about 15,890 (276)

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

open access: yesAdvanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu   +8 more
wiley   +1 more source

Separation and Identification of Folate Coenzymes on DEAE-Sephadex

open access: yes, 1971
The separation of naturally occurring folates is achieved by column chromatography on DEAE-cellulose (diethylaminoethyl-C) and on TEAE-cellulose (triethylaminoethyl-C), and the separated fractions are quantitated and identified by microbiological assay ...
Bertino, J. R.   +3 more
core   +1 more source

Testing the content of vitamin A in dietary supplements

open access: yesJournal of Education, Health and Sport, 2019
Vitamins in the human body perform regulatory functions, determine the development, health and physical performance of the body. Most of them are not synthesised in the body, therefore they must be supplied with food. They interact with enzymes, which is
Marcin Ślifirczyk   +3 more
doaj   +3 more sources

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Electrochemical synthesis of coenzymes Qn by oxidation of tetramethoxy precursors

open access: yes, 2009
The electrochemical oxidation of tetramethoxy precursors (2) to coenzymes Q (n) (1) at a carbon anode was investigated both in a bench-scale batch electrochemical reactor and in a continuous recirculation reaction system equipped with a parallel-plate ...
GALIA, Alessandro   +3 more
core   +1 more source

B Vitamins and Their Roles in Gut Health

open access: yesMicroorganisms, 2022
B vitamins act as coenzymes in a myriad of cellular reactions. These include energy production, methyl donor generation, neurotransmitter synthesis, and immune functions.
Khandkar Shaharina Hossain   +2 more
doaj   +1 more source

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

open access: yesAdvanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li   +9 more
wiley   +1 more source

Transition-Metal-Catalyzed Regeneration of Nicotinamide Coenzymes with Hydrogen\u3csup\u3e1\u3c/sup\u3e

open access: yes, 2003
The nicotinamide coenzymes consumed in alcohol dehydrogenase catalyzed enantioselective reduction of ketones are expensive and thus require recycling.
Wagenknecht, Paul S.   +2 more
core   +1 more source

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

open access: yesAdvanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding   +7 more
wiley   +1 more source

Self-Incorporation of Coenzymes by Ribozymes [PDF]

open access: yes, 1995
RNA molecules that are assembled from the four standard nucleotides contain a limited number of chemical functional groups, a characteristic that is generally thought to restrict the potential for catalysis by ribozymes.
Joyce, Gerald F., Breaker, Ronald R.
core  

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